Thrombocytopenia during levetiracetam therapy

Epilepsy Research

Volumn 80, Issue 1, 2008, Pages 91-92

  Meschede, A ^a   Runge, U ^a   Sabolek, M ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Antiepileptic drug; Levetiracetam; Thrombocytopenia

Indexed keywords

CAPTOPRIL; CARBAMAZEPINE; ETIRACETAM; LEVODOPA; RIVASTIGMINE; VALPROIC ACID;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; COMBINATION CHEMOTHERAPY; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAM; FEMALE; HUMAN; MONOTHERAPY; PRIORITY JOURNAL; SYMPTOMATIC EPILEPSY; THROMBOCYTOPENIA;

ANTICONVULSANTS; EPILEPSY, COMPLEX PARTIAL; FEMALE; HUMANS; MIDDLE AGED; PIRACETAM; THROMBOCYTOPENIA;

EID: 44749083568     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2008.03.002     Document Type: Article

References (7)

1. Beran R.G., Berkovic S.F., Black A.B., Danta G., Hiersemenzel R., Schapel G.J., and Vajda F.J.E. Efficacy and safety of levetiracetam 1000-3000 mg/day in patients with refractory partial-onset seizures: a multicenter, open-label single-arm study. Epilepsy Res. 63 (2005) 1-9
2. Hartmann H., Schumacher U., and Seeck M. Verschlechterung einer Immunthrombopenie unter Monotherapie mit Levetiracetam. Aktuel Neurol. 29 (2002) 467-468
3. Heo K., Lee B.I., Yi S.D., Huh K., Kim J.M., Lee S.A., Shin D.J., Song H.K., Lee S.K., Kim J.Y., Lu S.j., Dubois C., and Tonner F. Efficacy and safety of levetiracetam as adjunctive treatment of refractory partial seizures in a multicentre open-label single-arm trial in Korean patients. Seizure 16 (2007) 402-409
4. Hirsch L.J., Arif H., Buchsmann R., Weintraub D., Lee J., Chang J.T., Resor S.R., and Bazil C.W. Effect of age and comedication on levetiracetam pharmacokinetics and tolerability. Epilepsia 48 (2007) 1351-1359
5. Kimland E., Höjeberg B., and von Euler M. Levetiracetam-induced thrombocytopenia. Epilepsia 45 (2004) 877-878
6. Nasreddine W., and Beydoun A. Valproate-induced thrombocytopenia: a prospective monotherapy study. Epilepsia (2007) (Epub November 21)
7. Tsai J.J., Jen D.J., Hsih M.S., Chen S.S., Hiersemenzel R., Edrich P., and Lai C.W. Efficacy and safety of levetiracetam (up to 2000 mg/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled study. Epilepsia 47 (2006) 72-81