Phospholipase A2-interacting weak neurotoxins from venom of monocled cobra Naja kaouthia display cell-specific cytotoxicity

Toxicon

Volumn 51, Issue 8, 2008, Pages 1538-1543

  Mukherjee, Ashis K ^a  

^a TEZPUR UNIVERSITY   (India)

Author keywords

Cobra venom; Cytotoxicity; Monocled cobra; Naja kaouthia; Sf9 cell; VERO cell; Weak neurotoxin

Indexed keywords

NEUROTOXIN; PHOSPHOLIPASE A2; POLYPEPTIDE; SNAKE VENOM; CYTOTOXIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN PURIFICATION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SNAKE; ANIMAL; CELL LINE; CERCOPITHECUS; CHEMISTRY; DRUG EFFECT; FRACTIONATION; INSECT; PH; VERO CELL;

HEXAPODA; MAMMALIA; NAJA KAOUTHIA;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; CHEMICAL FRACTIONATION; COBRA; COBRA VENOMS; CYTOTOXINS; HYDROGEN-ION CONCENTRATION; INSECTS; NEUROTOXINS; PHOSPHOLIPASES A2; SEQUENCE ALIGNMENT; VERO CELLS;

EID: 44649182111     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.03.014     Document Type: Article

References (19)

1. 2 from Indian monocled cobra (Naja kaouthia) venom. Toxicon 41 (2003) 81-91
2. 2-II), from Indian monocled cobra Naja kaouthia venom. Arch. Biochem. Biophys. 425 (2004) 1-13
3. Feofanov A., Sharonov G.V., Astapova M.V., Rodionov D.I., and Utkin Y.N. Cancer cell injury by cytotoxins from cobra venom is mediated through lysosomal damage. Biochem. J. 390 (2005) 11-18
4. Jeyaseelan K., Poh S.L., Nair R., and Armugam A. Structurally conserved α-neorotoxin genes encode functionally diverse proteins in the venom of Naja sputatrix. FEBS Lett. 553 (2003) 333-341
5. Karp G. Cell and Molecular Biology: Concepts and Experiments. third ed (2002), Wiley, New York
6. Klenk H.D., and Choppin P.W. Lipids of plasma membranes of monkey and hamster kidney cells and of parainfluenza virions grown in these cells. Virology 38 (1969) 255-268
7. Laemmli U.K. Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
8. Lauterwein J., and Wuthrick K. A possible structural basis for the different modes of action of neurotoxins and cardiotoxins from snake venoms. FEBS Lett. 93 (1978) 181-184
9. Marheineke K., Grunewald S., Christie W., and Reilander H. Lipid composition of Spodoptera frugiperda (Sf9) and Trichoplusia ni (Tn) insect cells used for baculovirus infection. FEBS Lett. 441 (1998) 49-52
10. Mukherjee A.K., and Maity CR. The composition of Naja naja venom samples from three districts of West Bengal, eastern India. Comp. Biochem. Physiol. 119A (1998) 621-627
11. Mukherjee A.K., and Maity C.R. Biochemical composition, lethality and pathophysiology of venom from two cobras-Naja naja and Naja kaouthia. Comp. Biochem. Physiol. 131 B (2002) 125-132
12. 2 molecules. Biochem. Biophys. Acta 1770 (2007) 187-195
13. Nirthanan S., Gopalakrishnokone P., Gwee M.C.E., Khoo H.E., and Kini R.M. Non-conventional toxins from Elapid venoms. Toxicon 41 (2003) 397-407
14. Notredame C., Higgins D., and Heringa J. T-coffee: a novel method for fast and accurate multiple sequence alignment. J. Mol. Biol. 302 (2000) 205-217
15. Ogay A.Y., Rzhevsky D.I., Murashev A.N., Tsetlin V.I., and Utkin Y.N. Weak neurotoxin from Naja kaouthia cobra venom affects haemodynamic regulation by acting on acetylcholine receptors. Toxicon 45 (2005) 93-99
16. Ohno M., Menez R., Ogawa T., Danse J.M., Shimohigashi Y., Fromen C., Ducancel F., Zinn-Justin S., DuLe M.H., Boulain J.C., Tamiya T., and Menez A. Molecular evolution of snake toxins is the functional diversity of snake toxins associated with a mechanism of accelerated evolution?. Prog. Nucleic Acid Res. Mol. Biol. 59 (1998) 307-364
17. Poh S.L., Mourier G., Thai R., Armugam A., Malgo J., Servent D., Jeyaseelan K., and Menez A. A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken α7 nicotinic acetylcholine receptors. Eur. J. Biochem. 269 (2002) 4247-4256
18. Tsetlin V. Snake venom alpha-neurotoxins and other three-finger proteins. Eur. J. Biochem. 264 (1999) 281-286
19. Utkin Y.N., Kukhtina V.V., Maslennikov I.V., Eletsky A.V., Starkov V.G., Weise C., Franke P., Hucho F., and Tsetlin V.I. First tryptophan-containing weak neurotoxin from cobra venom. Toxicon 39 (2001) 921-927