Zinc cyanide mediated direct α-cyanation of isonicotinic acid N-oxide. Application to the synthesis of FYX-051, a xanthine oxidoreductase inhibitor

Tetrahedron Letters

Volumn 49, Issue 28, 2008, Pages 4369-4371

  Huo, Zhibao ^a   Kosugi, Teruo ^b   Yamamoto, Yoshinori ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b Fukuzyu Pharmaceuticals Co Ltd   (Japan)

Author keywords

Cyanation; 2 Cyanoisonicotinamide; Isonicotinic acid N oxide; Pyridine N oxide; Zinc cyanide

Indexed keywords

CYANIDE; FYX 051; ISONICOTINIC ACID; ISONICOTINIC ACID N OXIDE; XANTHINE OXIDASE INHIBITOR; ZINC CYANIDE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYANATION; SYNTHESIS;

EID: 44649165045     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.05.029     Document Type: Article

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