Microparticle photometry in a CMOS microsystem combining magnetic actuation and in situ optical detection

Sensors and Actuators, B: Chemical

Volumn 132, Issue 2, 2008, Pages 411-417

  Lehmann, U ^a   Sergio, M ^a   Pietrocola, S ^a   Dupont, E ^a   Niclass, C ^a   Gijs, M A M ^a   Charbon, E ^a  

^a EPFL   (Switzerland)

Author keywords

CMOS; Magnetism; Microfluidics; Microparticles; Optical detection; Photometry; SPAD

Indexed keywords

AVALANCHE DIODES; AVALANCHES (SNOWSLIDES); COMPUTER NETWORKS; FERROMAGNETISM; FLUIDICS; MAGNETIC BUBBLES; MAGNETIC DOMAINS; MAGNETIC MATERIALS; MICROFLUIDICS; NANOFLUIDICS; NANOSTRUCTURED MATERIALS; PHOTOMETERS; PHOTOMETRY; PHOTONS; SENSITIVITY ANALYSIS; SNOW;

ELSEVIER (CO); HIGH SENSITIVITY (HS); HYBRID CMOS; IN-SITU; INCIDENT LIGHT; MAGNETIC ACTUATION; MAGNETIC MICROPARTICLES; MAGNETIC PARTICLES; MICRO FLUIDIC SYSTEMS; MICRO PARTICLES; MICRO SYSTEMS; MICROPARTICLES (MP); OPTICAL DETECTION; PARTICLE PROPERTIES; PARTICLE VELOCITIES; PHOTON COUNTING; SIMULTANEOUS MEASUREMENTS; SINGLE PHOTON AVALANCHE DIODE (SPAD);

MAGNETISM;

EID: 44649148310     PISSN: 09254005     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.snb.2007.10.021     Document Type: Article

References (21)

1. Gijs M.A.M. Magnetic bead handling on-chip: new opportunities for analytical applications. Microfluidics Nanofluidics 1 1 (2004) 22-40
2. Deng T., Whitesides G.M., and Radhakrishnan M. Manipulation of magnetic microbeads in suspension using micromagnetic systems fabricated with soft lithography. Appl. Phys. Lett. 78 12 (2001) 1775-1777
3. Wirix-Speetjens R., Fyen W., Xu K.D., De Boeck J., and Borghs G. A force study of on-chip magnetic particle transport based on tapered conductors. IEEE Trans. Magn. 41 10 (2005) 4128-4133
4. Lehmann U., Vandevyver C., Parashar V.K., and Gijs M.A.M. Droplet-based DNA purification in a magnetic lab-on-a-chip. Angew. Chem. Int. Edit. 45 19 (2006) 3062-3067
5. Choi J.W., Ahn C.H., Bhansali S., and Henderson H.T. A new magnetic bead-based, filterless bio-separator with planar electromagnet surfaces for integrated bio-detection systems. Sens. Actuator B 68 (2000) 34-39
6. Smistrup K., Kjeldsen B.G., Reimers J.L., Dufva M., Petersen J., and Hansen M.F. On-chip magnetic bead microarray using hydrodynamic focusing in a passive magnetic separator. Lab Chip 5 11 (2005) 1315-1319
7. Graham D.L., Ferreira H.A., Feliciano N., Freitas P.P., Clarke L.A., and Amaral M.D. Magnetic field-assisted DNA hybridisation and simultaneous detection using micron-sized spin-valve sensors and magnetic nanoparticles. Sens. Actuator B: Chem. 107 2 (2005) 936-944
8. Rife J.C., and Miller M.M. Design and performance of GMR sensors for the detection of magnetic microbeads in biosensors. Sens. Actuator A 107 (2003) 209-218
9. Ferreira H.A., Feliciano N., Graham D.L., and Freitas P.P. Effect of spin-valve sensor magnetostatic fields on nanobead detection for biochip applications. J. Appl. Phys. 97 10 (2005)
10. Wirix-Speetjens R., Fyen W., De Boeck J., and Borghs G. Single magnetic particle detection: experimental verification of simulated behavior. J. Appl. Phys. 99 10 (2006)
11. Lee H., Purdon A.M., and Westervelt R.M. Micromanipulation of biological systems with microelectromagnets. IEEE Trans. Magn. 40 4 (2004) 2991-2993
12. Lee H., Liu Y., Ham D., and Werstervelt R.M. Integrated cell manipulation system-CMOS/microfluidic hybrid. Lab Chip 7 (2007) 331-337
13. Rida A., Fernandez V., and Gijs M.A.M. Long-range transport of magnetic microbeads using simple planar coils placed in a uniform magnetostatic field. Appl. Phys. Lett. 83 12 (2003) 2396
14. Rochas A., Gani M., Furrer B., Besse P.A., Popovic R.S., Ribordy G., and Gisin N. Single photon detector fabricated in a complementary metal-oxide-semiconductor high-voltage technology. Rev. Sci. Instrum. 74 7 (2003) 3263-3270
15. Sandor Z. Estimations of orbital parameters of exoplanets from transit photometry by using dynamical constraints. Celes. Mech. Dyn. Astron. 95 1-4 (2006) 273-285
16. Niclass C., Sergio M., and Charbon E. A single photon avalanche diode array fabricated in 0.35-μm CMOS and based on an event-driven readout for TCSPC experiments. Proceedings of the SPIE on Advanced Photon Counting Techniques, vol. 6372 (2006) 63720S
17. Sartoretti P., and Schneider J. On the detection of satellites of extrasolar planets with the method of transits. Astron. Astrophys. Suppl. Ser. 134 3 (1999) 553-560
18. McCloskey K.E., and Chalmers J.J. Magnetic cell separation: characterization of magnetophoretic mobility. Anal. Chem. 75 (2003) 6868-6874
19. Costa L.C., Valente M., Sa M.A., and Henry F. Electrical and magnetic properties of polystyrene doped with iron nanoparticles. Polym. Bull. 57 6 (2006) 881-887
20. Chun H.G., Chung T.D., and Kim H.C. Cytometry and velocimetry on a microfluidic chip using polyelectrolytic salt bridges. Anal. Chem. 77 8 (2005) 2490-2495
21. Clement J.H., Schwalbe M., Buske N., Wagner K., Schnabelrauch M., Gornert P., Kliche K.O., Pachmann K., Weitschies W., and Hoffken K. Differential interaction of magnetic nanoparticles with tumor cells and peripheral blood cells. J. Cancer Res. Clin. Oncol. 132 5 (2006) 287-292