Bone and cartilage turnover markers, bone mineral density, and radiographic damage in men with ankylosing spondylitis

Yonsei Medical Journal

Volumn 49, Issue 2, 2008, Pages 288-294

  Park, Min Chan ^a   Chung, Soo Jin ^a   Park, Yong Beom ^a   Lee, Soo Kon ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Ankylosing spondylitis; Bone mineral density; C terminal telopeptide fragments of type I collagen; C terminal telopeptide fragments of type II collagen; Radiographic damage

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; CARBOXY TERMINAL TELOPEPTIDE; COLLAGEN TYPE 2; OSTEOCALCIN;

ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; ANKYLOSING SPONDYLITIS; ARTICLE; BIOCHEMISTRY; BONE DENSITY; BONE TURNOVER; CARTILAGE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMUR; HUMAN; LUMBAR SPINE; MALE; PREVALENCE; PROTEIN BLOOD LEVEL; SPINE RADIOGRAPHY; STATISTICAL SIGNIFICANCE; URINALYSIS;

ADOLESCENT; ADULT; ALKALINE PHOSPHATASE; BIOLOGICAL MARKERS; BONE AND BONES; BONE DENSITY; CARTILAGE; COLLAGEN TYPE I; COLLAGEN TYPE II; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOASSAY; MALE; OSTEOCALCIN; SPONDYLITIS, ANKYLOSING;

EID: 44649113915     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2008.49.2.288     Document Type: Article

References (28)

1. Calin A. Osteoporosis and ankylosing spondylitis. Br J Rheumatol 1991;30:318-9.
2. El Maghraoui A, Borderie D, Cherruau B, Edouard R, Dougados M, Roux C. Osteoporosis, body composition, and bone turnover in ankylosing spondylitis. J Rheumatol 1999;26:2205-9.
3. Ruof J, Stucki G. Validity aspects of erythrocyte sedimentation rate and C-reactive protein in ankylosing spondylitis: a literature review. J Rheumatol 1999;26: 966-70.
4. Geusens P, Vosse D, van der Linden S. Osteoporosis and vertebral fractures in ankylosing spondylitis. Curr Opin Rheumatol 2007;19:335-9.
5. Karberg K, Zochling J, Sieper J, Felsenberg D, Braun J. Bone loss is detected more frequently in patients with ankylosing spondylitis with syndesmophytes. J Rheumatol 2005;32:1290-8.
6. Capaci K, Hepguler S, Argin M, Tas I. Bone mineral density in mild and advanced ankylosing spondylitis. Yonsei Med J 2003;44:379-84.
7. Maksymowych WP. Ankylosing spondylitis-at the interface of bone and cartilage. J Rheumatol 2000;27: 2295-301.
8. Christenson RH. Biochemical markers of bone metabolism: an overview. Clin Biochem 1997;30:573-93.
9. Bonde M, Qvist P, Fledelius C, Riis BJ, Christiansen C. Immunoassay for quantifying type I collagen degradation products in urine evaluated. Clin Chem 1994;40: 2022-5.
10. Christgau S, Garnero P, Fledelius C, Moniz C, Ensig M, Gineyts E, et al. Collagen type II C-telopeptide fragments as an index of cartilage degradation. Bone 2001;29: 209-15.
11. Garnero P, Gineyts E, Christgau S, Finck B, Delmas PD. Association of baseline levels of urinary glucosyl-galactosyl-pyridinoline and type II collagen C-telopeptide with progression of joint destruction in patients with early rheumatoid arthritis. Arthritis Rheum 2002;46:21-30.
12. Landewe R, Geusens P, Boers M, van der Heijde D, Lems W, te Koppele J, et al. Markers for type II collagen breakdown predict the effect of disease-modifying treatment on long-term radiographic progression in patients with rheumatoid arthritis. Arthritis Rheum 2004;50:1390-9.
13. Garnero P, Piperno M, Gineyts E, Christgau S, Delmas PD, Vignon E. Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage. Ann Rheum Dis 2001;60:619-26.
14. Lehmann HJ, Mouritzen U, Christgau S, Cloos PA, Christiansen C. Effect of bisphosphonates on cartilage turnover assessed with a newly developed assay for collagen type II degradation products. Ann Rheum Dis 2002;61:530-3.
15. Lange U, Teichmann J, Stracke H. Correlation between plasma TNF-alpha, IGF-1, biochemical markers of bone metabolism, markers of inflammation/ disease activity, and clinical manifestations in ankylosing spondylitis. Eur J Med Res 2000;5:507-11.
16. Grisar J, Bernecker PM, Aringer M, Redlich K, Sedlak M, Wolozcszuk W, et al. Ankylosing spondylitis, psoriatic arthritis, and reactive arthritis show increased bone resorption, but differ with regard to bone formation. J Rheumatol 2002;29:1430-6.
17. Toussirot E, Ricard-Blum S, Dumoulin G, Cedoz JP, Wendling D. Relationship between urinary pyridinium crosslinks, disease activity and disease subsets of ankylosing spondylitis. Rheumatology (Oxford) 1999; 38:21-7.
18. Marhoffer W, Stracke H, Masoud I, Scheja M, Graef V, Bolten W, et al. Evidence of impaired cartilage/bone turnover in patients with active ankylosing spondylitis. Ann Rheum Dis 1995;54:556-9.
19. van der Linden S, Valkenburg HA, Cats A. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum 1984;27:361-8.
20. Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. J Rheumatol 1994;21:2286-91.
21. Calin A, Mackay K, Santos H, Brophy S. A new dimension to outcome: application of the Bath Ankylosing Spondylitis Radiology Index. J Rheumatol 1999;26:988-92.
22. Bronson WD, Walker SE, Hillman LS, Keisler D, Hoyt T, Allen SH. Bone mineral density and biochemical markers of bone metabolism in ankylosing spondylitis, J Rheumatol 1998;25:929-35.
23. Baek HJ, Kang SW, Lee YL, Shin KC, Lee EB, Yoo CD, et al. Osteopenia in men with mild and severe ankylosing spondylitis. Rheumatol Int 2005;26:30-4
24. Benjamin M, McGonagle D. The anatomical basis for disease localisation in seronegative spondyloarthropathy at entheses and related sites. J Anat 2001;199: 503-26.
25. Buckwalter JA, Hunziker EB. Articular cartilage morphology and biology. In: Archer CW, Caterson B, Benjamin M, Ralphs JR, editors. Biology of the synovial joint. Amsterdam: Harwood Academic Pulisher; 1999. p.75-100.
26. Poole AR. The histopathology of ankylosing spondylitis: are there unifying hypotheses? Am J Med Sci 1998;316: 228-33.
27. Kuon W, Kuhne M, Busch DH, Atagunduz P, Seipel M, Wu P, et al. Identification of novel human aggrecan T cell epitopes in HLA-B27 transgenic mice associated with spondyloarthropathy. J Immunol 2004;173:4859-66.
28. François RJ, Gardner DL, Degrave EJ, Bywaters EG. Histopathologic evidence that sacroiliitis in ankylosing spondylitis is not merely enthesitis. Arthritis Rheum 2000;43:2011-24.