Early and presymptomatic detection of Wilson's disease at the mandatory 3-year-old medical health care examination in Hokkaido Prefecture with the use of a novel automated urinary ceruloplasmin assay

Molecular Genetics and Metabolism

Volumn 94, Issue 3, 2008, Pages 363-367

  Nakayama, Kenji ^a   Kubota, Mitsuru ^b   Katoh, Yoshinobu ^a   Sawada, Yukiharu ^a   Saito, Akiko ^a   Nishimura, Kazuhiko ^a   Katsura, Eiji ^a   Ichihara, Naoshi ^a   Suzuki, Tomohiro ^a   Kouguchi, Hirokazu ^a   Tamura, Masahide ^a   Honma, Hiroshi ^a   Kanzaki, Setsuo ^c   Itami, Hitoshi ^c   Ohtake, Akihiko ^c   Kobayashi, Kunihiko ^b   Ariga, Tadashi ^b   Fujieda, Kenji ^d   Shimizu, Norikazu ^e   Aoki, Tsugutoshi ^f  

^a HOKKAIDO INSTITUTE OF PUBLIC HEALTH   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c Naska Co Ltd   (Japan)

^d ASAHIKAWA MEDICAL COLLEGE   (Japan)

^e TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f TOHO UNIVERSITY   (Japan)

Author keywords

ATP7B; Ceruloplasmin; Early detection; Genetic analysis; Medical health care examination; Molecular diagnosis; Polaprezinc; Screening; Urine; Wilson's disease

Indexed keywords

CERULOPLASMIN; CHELATING AGENT; COPPER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOSOMAL RECESSIVE DISORDER; BRAIN DAMAGE; CERULOPLASMIN BLOOD LEVEL; CHILD; CONTROLLED STUDY; COPPER BLOOD LEVEL; EARLY DIAGNOSIS; FERENCI SCORING SYSTEM; GENE MUTATION; HUMAN; JAPAN; LATEX AGGLUTINATION TEST; LIVER INJURY; MAJOR CLINICAL STUDY; MOLECULAR GENETICS; NORMAL VALUE; PEDIGREE; PERIODIC MEDICAL EXAMINATION; PRIORITY JOURNAL; QUALITY OF LIFE; SCORING SYSTEM; SCREENING TEST; SEQUENCE ANALYSIS; STATISTICAL ANALYSIS; URINALYSIS; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; ADOLESCENT; ADULT; AGE FACTORS; ALGORITHMS; AUTOMATION; CATION TRANSPORT PROTEINS; CERULOPLASMIN; CHILD; CHILD, PRESCHOOL; DIAGNOSTIC TECHNIQUES, DIGESTIVE SYSTEM; DNA MUTATIONAL ANALYSIS; EARLY DIAGNOSIS; FEMALE; HEPATOLENTICULAR DEGENERATION; HUMANS; JAPAN; MALE; MANDATORY TESTING; PEDIGREE;

EID: 44649111099     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2008.03.002     Document Type: Article

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