Prevalence of brain metastases immediately before prophylactic cranial irradiation in limited disease small cell lung cancer patients with complete remission to chemoradiotherapy: A single institution experience

Journal of Thoracic Oncology

Volumn 3, Issue 6, 2008, Pages 652-655

  Manapov, Farkhat ^a   Klautke, Gunther ^a   Fietkau, Rainer ^a,b,c  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Prophylactic cranial irradiation; Small cell lung cancer

Indexed keywords

CARBOPLATIN; CISPLATIN; ETOPOSIDE; GADOLINIUM PENTETATE; IRINOTECAN; TOPOTECAN; VINCRISTINE;

ADULT; AGED; ARTICLE; BRAIN METASTASIS; CANCER RADIOTHERAPY; CANCER REGRESSION; CANCER RELAPSE; COMBINATION CHEMOTHERAPY; CONTINUOUS INFUSION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MONOTHERAPY; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PRIORITY JOURNAL; PROGNOSIS; PROPHYLAXIS; RADIATION DOSE; SKULL IRRADIATION; TREATMENT RESPONSE;

EID: 44649092672     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3181757a76     Document Type: Article

References (14)

1. Komaki R, Cox JD, Whitson W. Risk of brain metastasis in small cell carcinoma of the lung related to length of survival and prophylactic irradiation. Cancer Treat Rep 1981;65:811-814.
2. van Oosterhout AG, van de Pol M, ten Velde GP, Twijnstra A. Neurologic disorders in 203 consecutive patients with small cell lung cancer. Results of a longitudinal study. Cancer 1996;77:1434-1441.
3. Hochstenbag MMH, Twijnstra A, Wilmink JT. Asymptomatic brain metastases (BM) in small cell lung cancer (SCLC): MR-imaging is useful at initial diagnosis. J Neurooncol 2000;48:243-248.
4. Jackman DM, Johnson BE. Small cell lung cancer. Lancet 2005;366:1385-1396.
5. Auperin A, Arriagada R, Pignon JP, et al. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic cranial irradiation overview collaborative group. N Eng J Med 1999;12:476-484.
6. Lee JS, Umsawasdi T, Barkley HT Jr, et al. Timing of elective brain irradiation: a critical factor for brain metastasis-free survival in small cell lung cancer. Int J Radiat Oncol Biol Phys 1987;13:697-704.
7. Suwinski R, Lee SP, Withers HR. Dose-response relationship for prophylactic cranial irradiation in small cell lung cancer. Int J Radiat Oncol Biol Phys 1998;40:797-806.
8. Meert AP, Paesmans M, Martin B, et al. Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis. BMC Cancer 2001;1:5.
9. Klautke G, Fahndrich S, Semrau S, Büscher C, Virchow C, Fietkau R. Simultaneous chemoradiotherapy with irinotecan and cisplatin in limited disease small cell lung cancer: a phase I study. Lung Cancer 2006;53:183-188.
10. Grüschow K, Klautke G, Fietkau R. Phase I/II clinical trial of concurrent radiochemotherapy in combination with topotecan for the treatment of brain metastases. Eur J Cancer 2002;38:367-374.
11. Simon GR, Wagner H. Small cell lung cancer. Chest 2003;123:259S-271S.
12. Baas P, Belderbos JS, Senan S, et al. Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: a Dutsch multicenter phase II study. Br J Cancer 2006;13:625-630.
13. Seute T, Leffers P, Wilmink JT, ten Velde GP, Twijnstra A. Response of asymptomatic brain metastases from small-cell lung cancer to systemic first-line chemotherapy. J Clin Oncol 2006;24:2079-2083.
14. Ball DL, Matthews JP. Prophylactic cranial irradiation: more questions than answers. Semin Radiat Oncol 1995;5:61-68.