Cloud point extraction-HPLC method for determination and pharmacokinetic study of flurbiprofen in rat plasma after oral and transdermal administration

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 868, Issue 1-2, 2008, Pages 64-69

  Han, Fei ^a   Yin, Ran ^a   Shi, Xiao lei ^a   Jia, Qiang ^a   Liu, Hong zhuo ^a   Yao, Hui min ^a   Xu, Lu ^a   Li, San ming ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Cloud point extraction; Flurbiprofen; Genapol X 080; HPLC UV; Pharmacokinetics

Indexed keywords

ANTIBIOTICS; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONIONIC SURFACTANTS; PHARMACOKINETICS; SOLVENTS;

CLOUD-POINT EXTRACTION; FLURBIPROFEN; GENAPOL X-080;

CLOUDS;

FLURBIPROFEN; NONIONIC SURFACTANT;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLURBIPROFEN; RATS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET;

RATTUS;

EID: 44449169386     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.04.024     Document Type: Article

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