Potency of SMP-601, a novel carbapenem, in hematogenous murine bronchopneumonia caused by methicillin-resistant and vancomycin-intermediate Staphylococcus aureus

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 6, 2008, Pages 2163-2168

  Kihara, Rie ^a   Yanagihara, Katsunori ^a,b   Morinaga, Yoshitomo ^a   Araki, Nobuko ^a   Nakamura, Shigeki ^a   Seki, Masafumi ^a   Izumikawa, Koichi ^a   Kakeya, Hiroshi ^a   Yamamoto, Yoshihiro ^a   Tsukamoto, Kazuhiro ^a   Kamihira, Shimeru ^a   Kohno, Shigeru ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 [3 (1 AMINOCYCLOPROPYL) 1 PYRROLIDINYL] 1 (2 FLUOROCYCLOPROPYL) 1,4 DIHYDRO 8 METHOXY 4 OXO 3 QUINOLINECARBOXYLIC ACID; CARBAPENEM; CYCLOPHOSPHAMIDE; DALFOPRISTIN PLUS QUINUPRISTIN; DQ 113; METICILLIN; OXAZOLIDINONE DERIVATIVE; SMP 601; VANCOMYCIN;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BACTERIAL COUNT; BRONCHOPNEUMONIA; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG TISSUE LEVEL; HISTOPATHOLOGY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; ANTI-BACTERIAL AGENTS; BLOOD-BORNE PATHOGENS; BRONCHOPNEUMONIA; CARBAPENEMS; COLONY COUNT, MICROBIAL; DISEASE MODELS, ANIMAL; HUMANS; LUNG; MALE; METHICILLIN RESISTANCE; MICE; PNEUMONIA, STAPHYLOCOCCAL; SPECIFIC PATHOGEN-FREE ORGANISMS; STAPHYLOCOCCUS AUREUS; TREATMENT OUTCOME; VANCOMYCIN; VANCOMYCIN RESISTANCE;

EID: 44449167059     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01532-07     Document Type: Article

References (14)

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