Frequency-swept HMQC sequences for high-throughput NMR analysis

Magnetic Resonance in Chemistry

Volumn 46, Issue 6, 2008, Pages 558-563

  Spitzer, Timothy D ^a   Rutkowske, Randy D ^a   Dorsey, George F ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

13C; 1H; Adiabatic; Frequency swept pulses; High throughput; HMQC; J compensation; NMR

Indexed keywords

THROUGHPUT;

13C; 1H; ADIABATIC; FREQUENCY SWEEP; FREQUENCY-SWEEP PULSE; HIGH-THROUGHPUT; HMQC; J COMPENSATION; NMR ANALYSIS; ROBUST PERFORMANCE;

CARBON;

CARBON; PROTON;

ALGORITHM; ARTICLE; CHEMISTRY; EVALUATION; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SIGNAL PROCESSING;

ALGORITHMS; CARBON ISOTOPES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTONS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SIGNAL PROCESSING, COMPUTER-ASSISTED;

EID: 44449142556     PISSN: 07491581     EISSN: 1097458X     Source Type: Journal    
DOI: 10.1002/mrc.2214     Document Type: Article

References (18)

1. T. Spitzer, A. Sefler, R. Rutkowske, Magn. Reson. Chem. 2001, 39, 530.
2. H. Kessler, P. Schmieder, M. Kurz, J. Magn. Reson. 1989, 85, 400.
3. P. Schmieder, T. Domke, DG. Norris, M. Kurz, H. Kesslear, D. Leibfritz, J. Magn. Reson. 1991, 93, 430.
4. T. Parella, F. Sanchez-Ferrando, A. Virgili, J. Magn. Reson., Ser. B 1995, 109, 88.
5. X. Zhang, C. Wang, J. Magn. Reson. 1991, 91, 618.
6. E. Kupce, Methods Enzymol. 2001, 338, 82.
7. M. Zweckstetter, T. Holak, J. Biomol. NMR 1999, 15, 331.
8. E. Kupce, R. Freeman, J. Magn. Reson. 1997, 127, 36.
9. C. Zwahlen, P. Legault, S. Vincent, J. Greenblatt, R. Konrat, L. Kay, J. Am. Chem. Soc. 1997, 119, 6711.
10. R. Boyer, R. Johnson, K. Krishnamurthy, J. Magn. Reson. 2003, 165, 253.
11. E. Kupce, R. Freeman, J. Magn. Reson., Ser. A 1995, 115, 273.
12. L. Allen, J. Eberly, in Optical Resonance and Two-level Atoms, Wiley: New York, 1975, pp101.
13. J. Baum, R. Tycko, A. Pines, J. Chem. Phys. 1983, 79, 4643.
14. J. Baum, R. Tycko, A. Pines, Phys. Rev. A 1985, 32, 3435.
15. V. van Zijl, T-L. Hwang, M. Johnson, M. Garwood, J. Am. Chem. Soc. 1996, 118, 5510.
16. T. Spitzer, R. Rutkowske, G. Dorsey, Small Molecule NMR Conference, Verona, Italy, September 2005.
17. H. Hu, V. Krishnamurthy, Small Molecule NMR Conference, Burlington, Vermont, USA, September 2006.
18. K. Cano, M. Smith, AJ. Shaka, J. Magn. Reson. 2002, 155, 131.