Two nucleotide substitutions in the A-site of yeast 18S rRNA affect translation and differentiate the interaction of ribosomes with aminoglycoside antibiotics

Biochimie

Volumn 90, Issue 6, 2008, Pages 908-917

  Tselika, S ^a   Konstantinidis, T C ^a   Synetos, D ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

Footprinting analysis; Paromomycin; Ribosomal RNA; Saccharomyces cerevisiae; Tobramycin; Translational fidelity

Indexed keywords

AMINOGLYCOSIDE; HYGROMYCIN; NUCLEOTIDE; PAROMOMYCIN; PEPTIDYLTRANSFERASE; RNA 18S; TOBRAMYCIN;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE INTERACTION; GENE MUTATION; GENE TRANSLOCATION; NONHUMAN; RIBOSOME; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; TETRAHYMENA THERMOPHILA; WILD TYPE; YEAST;

ANTI-BACTERIAL AGENTS; CELL PROLIFERATION; MUTATION; PAROMOMYCIN; PEPTIDYL TRANSFERASES; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES; RNA, FUNGAL; RNA, RIBOSOMAL, 18S; RNA, TRANSFER, AMINO ACYL; SACCHAROMYCES CEREVISIAE; TOBRAMYCIN;

ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE; TETRAHYMENA THERMOPHILA;

EID: 44449133045     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2008.02.010     Document Type: Article

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