A cost-effectiveness analysis of propofol versus midazolam for procedural sedation in the Emergency Department

Academic Emergency Medicine

Volumn 15, Issue 1, 2008, Pages 32-39

  Hohl, Corinne Michèle ^a   Nosyk, Bohdan ^b   Sadatsafavi, Mohsen ^c   Anis, Aslam Hayat ^b,d  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b Center for Health Evaluation and Outcome Sciences

^c VANCOUVER COASTAL HEALTH RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Conscious sedation; Cost effectiveness analysis; Midazolam; Procedural sedation; Propofol; Resource utilization

Indexed keywords

MIDAZOLAM; PROPOFOL; HYPNOTIC SEDATIVE AGENT;

ARTICLE; ASPIRATION PNEUMONIA; COST CONTROL; COST EFFECTIVENESS ANALYSIS; DISABILITY; DRUG COST; ECONOMIC EVALUATION; EMERGENCY WARD; HEALTH CARE COST; HEALTH CARE UTILIZATION; HOSPITAL ADMINISTRATOR; HUMAN; INTUBATION; MEDICAL FEE; MEDICAL RECORD REVIEW; MONTE CARLO METHOD; PAIN; PRIORITY JOURNAL; PROCEDURAL SEDATION; QUALITY ADJUSTED LIFE YEAR; RESOURCE ALLOCATION; SEDATION; SENSITIVITY ANALYSIS; SIDE EFFECT; TREATMENT FAILURE; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; COMPARATIVE STUDY; CONSCIOUS SEDATION; COST BENEFIT ANALYSIS; ECONOMICS; EMERGENCY HEALTH SERVICE; EVALUATION; INSTRUMENTATION; NORTH AMERICA;

CONSCIOUS SEDATION; COST-BENEFIT ANALYSIS; DRUG COSTS; EMERGENCY SERVICE, HOSPITAL; HUMANS; HYPNOTICS AND SEDATIVES; MIDAZOLAM; NORTH AMERICA; PROPOFOL;

EID: 44449126822     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2007.00023.x     Document Type: Article

References (25)

1. Campbell SG, Magee KD, Kovacs GJ, et al. Procedural sedation and analgesia in a Canadian adult tertiary care emergency department: a case series. Can J Emerg Med. 2006; 8(2):85-93.
2. Innes G, Murphy M, Nijssen-Jordan C, Ducharme J, Drummond A. Procedural sedation and analgesia in the emergency department. Canadian consensus guidelines. J Emerg Med. 1999; 17(1):145-56.
3. Paris PM, Yealy DM. A procedural sedation and analgesia fasting consensus advisory: one small step for emergency medicine, one giant challenge remaining. Ann Emerg Med. 2007; 49(4):465-7.
4. Brown L, Denmark T, Wittlake W, Vargas E, Watson T, Crabb J. Procedural sedation use in the ED: management of pediatric ear and nose foreign bodies. Am J Emerg Med. 2004; 22(4):310-4.
5. Moloney T, Rogers D. Medical technology-a different view of the contentious debate over costs. N Engl J Med. 1979; 301:1413-9.
6. Angell M. Cost containment and the physician. JAMA. 1985; 254:1203-7.
7. Hohl CM, Sadatsafavi M, Nosyk B, Anis AH. Safety and clinical effectiveness of midazolam versus propofol for procedural sedation in the emergency department: a systematic review. Acad Emerg Med. 2008; 15:1-8.
8. Taylor DM, O'Brien D, Ritchie P, Pasco J, Cameron PA. Propofol versus midazolam/fentanyl for reduction of anterior shoulder dislocation. Acad Emerg Med. 2005; 12:13-9.
9. Holger JS, Satterlee PA, Haugen S. Nursing use between 2 methods of procedural sedation: midazolam versus propofol. Am J Emerg Med. 2005; 23(3):248-52.
10. Coll-Vinent B, Sala X, Fernandez C, et al. Sedation for cardioversion in the emergency department: analysis of effectiveness in four protocols. Ann Emerg Med. 2003; 42:767-72.
11. Parlak M, Parlak I, Erdur B, Ergin A, Sagiroglu E. Age effect on efficacy and side effects of two sedation and analgesia protocols on patients going through cardioversion: a randomized clinical trial. Acad Emerg Med. 2006; 13:493-9.
12. Ramsay M, Savage T, Simpson B, Goodwin R. Controlled sedation with alphaxalone-alphadalone. Br Med J. 1974; 2:656-9.
13. Thomas K, Nosyk B, Fisher C, et al. Cost-effectiveness of surgery plus radiotherapy vs. radiotherapy alone for treatment of metastatic epidural spinal cord compression. Int J Radiat Oncol Biol Phys. 2006; 66(4):1212-8.
14. Anis A, Sun H, Singh S, Woolcott J, Nosyk B, Brisson M. A cost-utility analysis of losartan versus atenolol in the treatment of hypertension. Pharmacoeconomics. 2006; 24(4):387-400.
15. British Columbia Nurses Union. Provincial Agreement. Available at: http://www.bcnu.org/contracts_services/default.htm. Accessed Apr 10, 2007.
16. Health Employers Association of British Columbia. Collective Agreement, Version 9. Vancouver, BC, 2006. Available at: http://www.heabc.bc.ca/Page22. aspx. Accessed Jun 25, 2007.
17. Shalansky K, Hill S (eds). Formulary of Vancouver General Hospital. Vancouver, 2005.
18. British Columbia Medical Association. Guide to Fees 2004. Available at: http://https://www.bcma.org/members/bcma_information/fee_guide/ current_fee_guide.htm. Accessed, 2004.
19. Frazee B, Park R, Lowery D, Baire M. Propofol for deep procedural sedation in the ED. Am J Emerg Med. 2005; 23(2):190-5.
20. Pershad J, Todd K, Waters T. Cost-effectiveness analysis of sedation and analgesia regimens during fracture manipulation in the pediatric emergency department. Pediatr Emerg Care. 2006; 22(10):729-36.
21. Health Canada. Drugs & Health Products. Canadian Adverse Reaction Newsletter. Available at: http://www.hc-sc.gc.ca/dhp-mps/medeff/bulletin/carn- bcei_index_e.html. Accessed Mar 30, 2007.
22. Canadian Association of Emergency Physicians and National Emergency Nurses Affiliation. Joint Position Statement on emergency department over-crowding. Can J Emerg Med. 2001; 3(2):82-8.
23. Bodenheimer T. High and rising health care costs. Part 1: seeking an explanation. Ann Intern Med. 2005; 142(10):847-54.
24. Morgan S. Canadian prescription drug costs surpass 18 billion dollars. Can Med Assoc J. 2005; 172(10):1323-4.
25. Cremieux PY, Ouellette P, Petit P. Do drugs reduce utilization of other healthcare resources? Pharmacoeconomics. 2007; 25(3):209-21.