Low-volume hydrodynamic gene delivery to the rat liver via an isolated segment of the inferior vena cava: Efficiency, cardiovascular response and intrahepatic vascular dynamics

Journal of Gene Medicine

Volumn 10, Issue 5, 2008, Pages 540-550

  Sawyer, Greta J ^a   Grehan, Aidan ^b   Dong, Xuebin ^a   Whitehorne, Michael ^b   Seddon, Michael ^a   Shah, Ajay M ^a   Zhang, Xiaohong ^a   Salehi, Siamak ^a   Fabre, John W ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Blood pressure; Cardiovascular; Electrocardiogram; Gene therapy; Hydrodynamic gene delivery; Liver; Volume

Indexed keywords

DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CARDIOVASCULAR RESPONSE; COMPLETE HEART BLOCK; CONTROLLED STUDY; DNA VECTOR; ELECTROCARDIOGRAM; GENE EXPRESSION; HEART RATE; HEMODYNAMICS; HYDRODYNAMICS BASED TRANSFECTION; INFERIOR CAVA VEIN; INTERMETHOD COMPARISON; LIVER FUNCTION; MALE; NONHUMAN; PLASMID; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; PULSE RATE; RAT;

ANIMALS; BLOOD PRESSURE; CARDIOVASCULAR PHYSIOLOGY; DNA; ELECTROCARDIOGRAPHY; GENE THERAPY; HEART RATE; INFUSIONS, INTRAVENOUS; LIVER; MALE; RATS; RATS, INBRED STRAINS; VENA CAVA, INFERIOR;

RATTUS;

EID: 44449113673     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1176     Document Type: Article

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