Use of tissue microdialysis to investigate hyperlactataemia following paediatric cardiac surgery

Interactive Cardiovascular and Thoracic Surgery

Volumn 7, Issue 3, 2008, Pages 384-388

  Hosein, Riad B M ^a   Morris, Kevin P ^a   Brawn, William J ^a   Barron, David J ^a  

^a BIRMINGHAM CHILDREN S HOSPITAL   (United Kingdom)

Author keywords

Fontan; Late onset hyperlactataemia; Microdialysis

Indexed keywords

LACTIC ACID; PYRUVIC ACID; CATECHOLAMINE; HEMOGLOBIN; HYDROCORTISONE;

ABDOMINAL WALL; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; FONTAN PROCEDURE; HEART INDEX; HEART SURGERY; HUMAN; HYPERLACTATEMIA; INTENSIVE CARE UNIT; MICRODIALYSIS; OXYGEN THERAPY; PEDIATRIC SURGERY; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; BODY TEMPERATURE; CARDIOPULMONARY BYPASS; CATECHOLAMINE BLOOD LEVEL; CATHETER; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; HEART OUTPUT; HEMOGLOBIN BLOOD LEVEL; HYDROCORTISONE BLOOD LEVEL; HYPOTHERMIA; LACTATE BLOOD LEVEL; STRESS;

ABDOMINAL WALL; ACIDOSIS, LACTIC; BIOLOGICAL MARKERS; CHILD, PRESCHOOL; EPINEPHRINE; FEASIBILITY STUDIES; FONTAN PROCEDURE; HUMANS; HYDROCORTISONE; LACTIC ACID; MICRODIALYSIS; NOREPINEPHRINE; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; PYRUVIC ACID; RESEARCH DESIGN; SUBCUTANEOUS TISSUE; TIME FACTORS; UP-REGULATION; VENTRICULAR FUNCTION;

EID: 44449113627     PISSN: 15699293     EISSN: None     Source Type: Journal    
DOI: 10.1510/icvts.2007.166264     Document Type: Conference Paper

References (15)

1. Hatherill M, Sajjanhar T, Tibby SM, Champion MP, Anderson D, Marsh MJ, Murdoch IA. Serum lactate as a predictor of mortality after paediatric cardiac surgery. Arch Dis Childhood 1997;77:235-238.
2. Dickson U, Stokes M, Morris K, Mitchell A. Serial lactate measurements during surgery involving deep hypothermic circulatory arrest. Paediatr Anaesth 2000:10:705.
3. Maillet J-M, Le Besnerais P, Cantoni M, Nataf P, Ruffenach A, Lessana A, Brodaty D. Frequency, risk factors and outcome of hyperlactatemia after cardiac surgery. Chest 2003:123:1361-1366.
4. Raper R, Cameron G, Walker D, Bowey J. Type B lactic acidosis following cardiopulmonary bypass. Crit Care Med 1997:25:46-51.
5. James JH, Luchette FA, McCarter FD, Fischer JE. Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet 1999:354:505-508.
6. Siegel LB, Dalton HJ, Hertzog JH, Hopkins RA, Hannan RL, Hauser GJ. Initial postoperative serum lactate predict survival in children after open heart surgery. Intensive Care Med 1996:22:1418-1423.
7. Duke T, Butt W, South M, Karl TR. Early markers of major adverse events in children after cardiac operations. J Thorac Cardiovasc Surg 1997:114:1042-1052.
8. Munoz R, Laussen PC, Palacio G, Zienko L, Piercey G, Wessel DL. Changes in whole blood lactate levels during cardiopulmonary bypass for surgery for congenital heart disease: an early indicator of morbidity and mortality. J Thorac Cardiovasc Surg 2000:119:155-162.
9. Jackman L, Shetty N, Davies P, Morris KP. Late onset hyperlactataemia following paediatric cardiac surgery. Intensive Care Med 2008 (in press).
10. Weil MH, Afifi AA. Experimental and clinical studies on lactate and pyruvate as indicators of the severity of acute circulatory failure (Shock). Circulation 1970:41:989-1001.
11. Chiolero RL, Revelly JP, Leverve X, Gersbach P, Cayeux MC, Berger MM, Tappy L. Effects of cardiogenic shock on lactate and glucose metabolism after heart surgery. Crit Care Med 2000:28:3784-3791.
12. Totaro RJ, Raper RF. Epinephrine-induced lactic acidosis following cardiopulmonary bypass. Crit Care Med 1997:25:1693-1699.
13. Levy B, Gibot S, Franck P, Cravoisy A, Bollaert PE. Relation between muscle Na+K+ ATPase activity and raised lactate concentrations in septic shock: a prospective study. Lancet 2005:365:871-875.
14. Arner P, Bolinder J. Microdialysis of adipose tissue. J Intern Med 1991;230:381-386.
15. Arner P, Kriegholm E, Engfeldt P. In situ studies of catecholamineinduced lipolysis in human adipose tissue using microdialysis. J Pharmacol Exp Ther 1990;254:284-288.