A double-blind placebo-controlled study into the efficacy of a homeopathic remedy for fear of firework noises in the dog (Canis familiaris)

Veterinary Journal

Volumn 177, Issue 1, 2008, Pages 80-88

  Cracknell, Nina R ^a   Mills, Daniel S ^a  

^a Department of Biological Sciences   (United Kingdom)

Author keywords

Dog; Fear; Fireworks; Homeopathy; Placebo

Indexed keywords

ANXIOLYTIC AGENT; BORATE SODIUM; CHAMOMILE; PHOSPHORUS; PLACEBO; PLANT EXTRACT; RHODODENDRON EXTRACT; SEDATIVE AGENT; VETERINARY DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOG; DOG DISEASE; DRUG EFFICACY; DRUG RESPONSE; FEAR; HOMEOPATHY; NOISE; NONHUMAN; OUTCOME ASSESSMENT; RHODODENDRON;

ANIMALS; BEHAVIOR, ANIMAL; DOGS; DOUBLE-BLIND METHOD; FEAR; FEMALE; FIREARMS; MALE; MATERIA MEDICA; NOISE; PLACEBOS; TREATMENT OUTCOME;

CANIS FAMILIARIS;

EID: 44449111221     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tvjl.2007.04.007     Document Type: Article

References (27)

1. Crowell-Davis S.L., Seibert L.M., Sung W., Parthasarathy V., and Curtis T.M. Use of clomipramine, alprazolam, and behavior modification for treatment of storm phobia in dogs. Journal of the American Veterinary Medical Association 222 (2003) 744-748
2. Cucherat M., Haugh M.C., Gooch M., and Boissel J.P. Evidence of clinical efficacy of homeopathy - A meta-analysis of clinical trials. European Journal of Clinical Pharmacology 56 (2000) 27-33
3. de Verdier K., Ohagen P., and Alenius S. No effect of a homeopathic preparation on neonatal calf diarrhoea in a randomized double blind, placebo-controlled trial. Acta Veterinaria Scandinavica 44 (2003) 97-101
4. Dworkin R.H., Katz J., and Gitlin M.J. Placebo response in clinical trials of depression and its implications for research on chronic neuropathic pain. Neurology 65 Suppl. 4 (2005) S7-S19
5. Gray B. Homeopathy; Science or Myth? vols. 7-16 (2000), North Atlantic Books, California, USA pp. 51-74
6. Gunn-Moore D.A., and Cameron M.E. A pilot study using synthetic feline facial pheromone for the management of feline idiopathic cystitis. Journal of Feline Medicine and Surgery 6 (2004) 133-138
7. Heath S.E. Fear-related behaviour problems in dogs: diagnosis and treatment. Feline and Canine Behavioural Medicine (2002), Henston, Peterborough 16-19
8. Hektoen L., Larsen S., Odegaard S.A., and Loken T. Comparison of homeopathy, placebo and antibiotic treatment of clinical mastitis in dairy cows. Methodological issues and results from a randomized-clinical trial. Journal of Veterinary Medicine Series A 51 (2004) 439-446
9. Hektoen L. Review of the current involvement of homeopathy in veterinary practice and research. The Veterinary Record 157 (2005) 224-229
10. Iimura, K., 2006. The nature of noise fear in the domestic dog. MPhil Thesis, University of Lincoln.
11. King J.N., Simpson B.S., Overall K.L., Appleby D., Pageat P., Ross C., Chaurand J.P., Heath S., Beata C., Weiss A.B., Muller G., Paris T., Bataille B.G., Parker J., Petit S., and Wren J. Treatment of separation anxiety in dogs with clomipramine: results from a prospective, randomized, double-blind, placebo-controlled, parallel-group, multicenter clinical trial. Applied Animal Behaviour Science 67 (2000) 255-275
12. Landsberg G.M., Hunthausen W., and Ackerman L. Fears and phobias. Handbook of Behaviour Problems of the Cat and Dog (2003), Saunders, Canada 227-268
13. Lerman D.C., and Iwata B.A. Prevalence of the extinction burst and it's attenuation during treatment. Journal of Applied Behavior Analysis 28 (1995) 93-94
14. Levine E.D., Ramos D., and Mills D.S. A prospective study of two self-help CD based desensitisation and counter-conditioning programmes with the use of dog appeasing pheromone for the treatment of firework fears in dogs (Canis familiaris). Applied Animal Behaviour Science 105 (2007) 311-329
15. McMillan F.D. The placebo effect in animals. Journal of the American Veterinary Medical Association 215 (1999) 992-999
16. Mills D.S., Estelles M.G., Coleshaw P.H., and Shorthouse C. Retrospective analysis of the treatment of firework fears in dogs. The Veterinary Record 153 (2003) 561-562
17. NCCAM, 2003. Questions and answers about homeopathy. (accessed 17.01.07).
18. Overall K.L. Fears, anxieties, and stereotypies. Clinical Behavioral Medicine for Small Animals (1997), Mosby, St. Louis 209-250
19. Overall K.L. Noise phobias in dogs. In: Horwitz D.F., Mills D.S., and Heath S. (Eds). BSAVA Manual of Canine and Feline Behavioural Medicine (2002), BSAVA, UK 164-172
20. Park R. Voodoo Science; The Road from Foolishness to Fraud (2000), Oxford University Press, New York
21. Poulton R., and Menzies R.G. Fears born and bred; toward a more inclusive theory of fear acquisition. Behaviour Research and Therapy 40 (2002) 197-208
22. RSPCA, 2006. Fireworks; Campaign Facts. http://www.rspca.org.uk/servlet/Satellite?pagename=RSPCA/RSPCARedirectan dpg=fireworkshomepageandmarker=1andarticleId=1131549066228 (accessed 03.05.06).
23. Scott D.W., Miller W.H., Senter D.A., Cook C.P., Kirker J.E., and Cobb S.M. Treatment of canine atopic dermatitis with a commercial homeopathic remedy: A single blinded, placebo controlled study. Canadian Veterinary Journal 43 (2002) 601-603
24. Sheppard G., and Mills D.S. Evaluation of dog appeasing pheromone as a potential treatment for dogs fearful of fireworks. The Veterinary Record 152 (2003) 432-436
25. Shull-Selcer E.A., and Stagg W. Advances in the understanding and treatment of noise phobias. Veterinary Clinics of North America (Small Animal Practice) 21 (1991) 353-367
26. Voith V.L., and Borchelt P.L. Fears and phobias in companion animals. Readings in Companion Animal Behaviour (1996), Trenton, USA 140-153
27. Walsh B.T., Seidman S.N., Sysko R., and Gould M. Placebo response in studies of major depression: Variable, substantial and growing. Journal of the American Medical Association 287 (2002) 1840-1847