Dramatic improvement of subcutaneous insulin resistance with nafamostat ointment treatment

Diabetes Care

Volumn 31, Issue 3, 2008, Pages

  Kawashima, Satoshi ^a   Kaneto, Hideaki ^a   Sakamoto, Ken'ya ^a   Honsho, Ikuko ^a   Yasuda, Tetsuyuki ^a   Kuroda, Akio ^a   Shiraiwa, Toshihiko ^a   Kasami, Ryuichi ^a   Matsuoka, Taka Aki ^a   Yamasaki, Yoshimitsu ^a   Matsuhisa, Munehide ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZULENE; GLUCOSE; INSULIN; INSULIN LISPRO; NAFAMSTAT; NAFAMSTAT MESILATE; PROTEINASE INHIBITOR; ANTIDIABETIC AGENT; GUANIDINE DERIVATIVE;

DISSEMINATED INTRAVASCULAR CLOTTING; DRUG ABSORPTION; DRUG BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; HUMAN; INSULIN RESISTANCE; LETTER; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREATITIS; BLOOD; CASE REPORT; FEMALE; MIDDLE AGED; OINTMENT; SUBCUTANEOUS DRUG ADMINISTRATION; TREATMENT OUTCOME;

DIABETES MELLITUS, TYPE 2; FEMALE; GUANIDINES; HUMANS; HYPOGLYCEMIC AGENTS; INJECTIONS, SUBCUTANEOUS; INSULIN; INSULIN RESISTANCE; MIDDLE AGED; OINTMENTS; TREATMENT OUTCOME;

EID: 44449102278     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc07-2161     Document Type: Letter

References (2)

1. Paulsen EP, Courtney JW, Duckworth WC: Insulin resistance caused by massive degradation of subcutaneous insulin. Diabetes 28:640-645, 1979
2. Takeyama M, Ishida T, Kokubu N, Komada F, Iwakawa S, Okumura K, Hori R: Enhanced bioavailability of subcutaneously injected insulin by pretreatment with ointment containing protease inhibitors. Pharm Res 8:60-64, 1991