Role of a novel multifunctional excipient poly(ethylene glycol)-block-oligo(vinyl sulfadimethoxine) in controlled release of lysozyme from PLGA microspheres

International Journal of Pharmaceutics

Volumn 358, Issue 1-2, 2008, Pages 50-59

  Taluja, Ajay ^a   Bae, You Han ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

Aqueous organic interface; Ion pairing; Lysozyme stabilization; PEG b oligo(vinyl sulfadimethoxine); PLGA microspheres; Release modulation

Indexed keywords

COPOLYMER; EXCIPIENT; LYSOZYME; MICROSPHERE; POLY(ETHYLENE GLYCOL) BLOCK OLIGO(VINYL SULFADIMETHOXINE); POLY(ETHYLENE GLYCOL) BLOCK POLY(ASPARTIC ACID); POLYELECTROLYTE; POLYGLACTIN; PROTEIN;

AQUEOUS SOLUTION; ARTICLE; CHROMATOGRAPHY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED RELEASE FORMULATION; EMULSION; ENCAPSULATION; ENZYMATIC ASSAY; ENZYME RELEASE; FLUORESCENCE ANALYSIS; MASS SPECTROMETRY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN STABILITY;

ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; DRUG STABILITY; EMULSIONS; EXCIPIENTS; LACTIC ACID; METHYLENE CHLORIDE; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MURAMIDASE; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; PROTEIN BINDING; SULFADIMETHOXINE; SURFACE-ACTIVE AGENTS;

EID: 44449084228     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2008.02.010     Document Type: Article

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