Suppressing effect of the cannabinoid CB 1 receptor antagonist, SR 141716, on alcohol's motivational properties in alcohol-preferring rats

European Journal of Pharmacology

Volumn 498, Issue 1-3, 2004, Pages 119-123

  Colombo, Giancarlo ^a   Vacca, Giovanni ^b   Serra, Salvatore ^b   Carai, Mauro A M ^b   Gessa, Gian Luigi ^a,b  

^a CNR Institute of Neuroscience   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Cannabinoid CB 1 receptor antagonist; Extinction responding for alcohol; rat; Sardinian alcohol preferring (sP); SR 141716

Indexed keywords

ALCOHOL; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; RIMONABANT; SUCROSE;

ALCOHOL CONSUMPTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; MALE; MOTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; TRAINING;

ALCOHOL DRINKING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING BEHAVIOR; EXTINCTION, PSYCHOLOGICAL; MALE; PIPERIDINES; PYRAZOLES; RATS; RECEPTOR, CANNABINOID, CB1; SELF ADMINISTRATION; SUCROSE;

EID: 4444376204     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.07.069     Document Type: Article

References (21)

1. 1) receptors Psychopharmacology 132 1997 104 106
2. 1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in ras Behav. Pharmacol. 13 2002 451 463
3. G. Colombo, R. Agabio, M. Fa, L. Guano, C. Lobina, A. Loche, R. Reali, and G.L. Gessa Reduction of voluntary alcohol intake in alcohol-preferring sP rats by the cannabinoid antagonist SR 141716 Alcohol Alcohol. 33 1998 126 130
4. G. Colombo, S. Serra, G. Brunetti, R. Gomez, S. Melis, G. Vacca, M.A.M. Carai, and G.L. Gessa Stimulation of voluntary ethanol intake by cannabinoid receptor agonists in ethanol-preferring sP rats Psychopharmacology 159 2002 181 187
5. C.S. Freedland, A.L. Sharpe, H.H. Samson, and L.J. Porrino Effects of SR 1417161A on alcohol and sucrose self-administration Alcohol., Clin. Exp. Res. 25 2001 277 282
6. J.E. Gallate, and I.S. McGregor The motivation for beer in rats: effects of ritanserin, naloxone and SR 141716 Psychopharmacology 142 1999 302 308
7. 1 receptor agonist Eur. J. Pharmacol. 370 1999 233 240
8. B.L. Hungund, B.S. Basavarajappa, C. Vadasz, G. Kunos, F. Rodriguez de Fonseca, G. Colombo, S. Serra, L. Parsons, and G.F. Koob Ethanol, endocannabinoids, and the cannabinoidergic signaling system Alcohol., Clin. Exp. Res. 26 2002 565 574
9. 1 receptor knockout exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens J. Neurochem. 84 2003 698 704
10. 1 cannabinoid receptor blockade on ethanol preference after chronic ethanol administration Alcohol., Clin. Exp. Res. 25 2001 1317 1323
11. 1 receptor knockout mice Neuropharmacology 46 2004 243 253
12. 1 receptor deleted mice Neurosci. Lett. 343 2003 216 218
13. 1 receptors in alcohol dependence and stress-stimulated ethanol drinking J. Neurosci. 23 2004 2453 2458
14. H.H. Samson Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats Alcohol., Clin. Exp. Res. 10 1986 436 442
15. H.H. Samson, A. Chappell, C. Czachowski, and A. Sharpe Measuring ethanol-seeking behavior: the effect of using repeated extinction trials Alcohol 24 2001 205 209
16. H.H. Samson, C.L. Czachowski, A. Chappell, and B. Legg Measuring the appetite strength of ethanol: use of an extinction trial procedure Alcohol 31 2003 77 86
17. S. Serra, M.A.M. Carai, G. Brunetti, R. Gomez, S. Melis, G. Vacca, G. Colombo, and G.L. Gessa The cannabinoid receptor antagonist SR 141716 prevents acquisition of drinking behavior in alcohol-preferring rats Eur. J. Pharmacol. 430 2001 369 371
18. 1 receptor antagonist, SR 141716, of alcohol deprivation effect in alcohol-preferring rats Eur. J. Pharmacol. 443 2002 95 97
19. G. Vacca, S. Serra, G. Brunetti, M.A.M. Carai, H.H. Samson, G.L. Gessa, and G. Colombo Operant self-administration of ethanol in Sardinian alcohol-preferring rats Alcohol., Clin. Exp. Res. 26 2002 1678 1685
20. L. Wang, J. Liu, J. Harvey-White, A. Zimmer, and G. Kunos Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice Proc. Natl. Acad. Sci. U. S. A. 100 2003 1393 1398
21. F. Weiss, and L.J. Porrino Behavioral neurobiology of alcohol addiction: recent advances and challenges J. Neurosci. 22 2002 3332 3337