Bone anabolic effects of S-40503, a novel nonsteroidal selective androgen receptor modulator (SARM), in rat models of osteoporosis

Biological and Pharmaceutical Bulletin

Volumn 26, Issue 11, 2003, Pages 1563-1569

  Hanada, Keigo ^a   Furuya, Kazuyuki ^a   Yamamoto, Noriko ^a   Nejishima, Hiroaki ^a   Ichikawa, Kiyonoshin ^a   Nakamura, Tsutomu ^a   Miyakawa, Motonori ^a   Amano, Seiji ^a   Sumita, Yuji ^a   Oguro, Nao ^a  

^a KAKEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Bone anabolic; Rat osteoporosis models; Reduced virilizing activity; S 40503; Selective androgen receptor modulator (SARM)

Indexed keywords

ANABOLIC AGENT; ANDROGEN RECEPTOR; ESTROGEN; S 40503; UNCLASSIFIED DRUG; ANDROSTANOLONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIOMECHANICS; BONE DENSITY; CORTICAL BONE; DRUG EFFECT; FEMALE; MALE; NONHUMAN; ORCHIECTOMY; OSSIFICATION; OSTEOPOROSIS; PROSTATE; RAT; TIME SERIES ANALYSIS; VIRILIZATION; ANIMAL; BONE; DISEASE MODEL; DOSE RESPONSE; PATHOPHYSIOLOGY; PHYSIOLOGY; RABBIT; SPRAGUE DAWLEY RAT;

ANABOLIC AGENTS; ANIMALS; BONE AND BONES; BONE DENSITY; DIHYDROTESTOSTERONE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MALE; OSTEOPOROSIS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN;

EID: 4444371195     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.26.1563     Document Type: Article

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