Determination of mitochondrial function and site-specific defects in electron transport in duodenal mitochondria in broilers with low and high feed efficiency

Poultry Science

Volumn 83, Issue 8, 2004, Pages 1394-1403

  Ojano Dirain, C P ^a   Iqbal, M ^a   Cawthon, D ^a   Swonger, S ^a   Wing, T ^b   Cooper, M ^b   Bottje, W ^a  

^a UNIVERSITY OF ARKANSAS   (United States)

^b Cobb Vantress Inc ^*  (United States)

Author keywords

Broiler; Duodenum mitochondria; Electron leak; Feed efficiency; Respiratory control ratio

Indexed keywords

ANIMALIA; GALLUS GALLUS;

EID: 4444370286     PISSN: 00325791     EISSN: None     Source Type: Journal    
DOI: 10.1093/ps/83.8.1394     Document Type: Article

References (53)

1. Barja, G. 1999. Kinetic measurement of mitochondrial oxygen radical production. Pages 533-534 in Methods in Aging Research. P. B. Yu, ed. CRC Press LLC, Washington, DC.
2. Bass, D. A., J. W. Parce, L. R. Dachatelet, P. Szejda, M. C. Seeds, and M. Thomas. 1983. Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation. J. Immunol. 130:1910-1915.
3. Benzi, G., and A. Moretti. 1995. Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and glutathione system. Free Radic. Biol. Med. 19:77-101.
4. Bilski, P., A. G. Belanger, and C. F. Chignell. 2002. Photosensititized oxidation of 2′,7′-dichlorofluorescin: Singlet oxygen does not contribute to the formation of fluorescent oxidation product 2′,7′-dichlorofluorescein. Free Radic. Biol. Med. 33:938-946.
5. Bottje, W., M. Iqbal, Z. X. Tang, D. Cawthon, R. Okimoto, T. Wing, and M. Cooper. 2002. Association of mitochondrial function with feed efficiency within a single genetic line of male broilers. Poult. Sci. 81:546-555.
6. Boveris, A., and B. Chance. 1973. The mitochondrial generation of hydrogen peroxide. Biochem. J. 134:707-711.
7. Braidot, E., E. Petrussa, A. Vianello, and F. Macri. 1999. Hydrogen peroxide generation by higher plant mitochondria oxidizing complex I or complex II substrates. FEBS Lett. 451:347-350.
8. Brown, D. R., S. K. DeNise, and R. G. McDaniel. 1986. Hepatic mitochondrial activity in two breeds of chicken. Poult. Sci. 65:613-615.
9. Cawthon, D., K. Beers, and W. G. Bottje. 2001. Electron transport chain defect and inefficient respiration may both underlie pulmonary hypertension syndrome (PHS)-associated mitochondrial dysfunction in broilers. Poult. Sci. 80:474-484.
10. Cawthon, D., R. McNew, K. W. Beers, and W. G. Bottje. 1999. Evidence of mitochondrial dysfunction in broilers with pulmonary hypertension syndrome (ascites): Effect of t-butyl hydroperoxide on function, glutathione and related thiols. Poult. Sci. 78:114-125.
11. Chance, B., H. Sies, and A. Boveris. 1979. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59:527-605.
12. Chapman, H. D., Z. B. Johnson, and J. L. McFarland. 2003. Improvements in the performance of commercial broilers in the USA: Analysis for the years 1997 to 2001. Poult. Sci. 82:50-53.
13. Davies, K. J. A., T. A. Quintanilha, G. A. Brooks, and L. Packer. 1982. Free radical and tissue damage produced by exercise. Biochem. Biophys. Res. Commun. 107:1198-1205.
14. Dziewiecki, C., and A. Kolataj. 1976. Rate of oxygen uptake by liver mitochondria in purebred chickens and in their hybrids. Genet. Pol. 17:219-224.
15. Emmerson, D. A. 1997. Commercial approaches to genetic selection for growth and feed conversion in domestic poultry. Poult. Sci. 76:1121-1125.
16. Estabrook, R. W. 1967. Mitochondrial respiratory control and the polarographic measurement of ADP:O ratios. Methods Enzymol. 10:41-47.
17. Fiegal, R. J., and B. L. Shapiro. 1979. Mitochondrial calcium uptake and oxygen consumption in cystic fibrosis. Nature. 278:276-277.
18. Havenstein, G. B., P. R. Ferket, and M. A. Qureshi. 2003. Growth, livability, and feed conversion of 1957 versus 2001 broilers when fed representative 1957 and 2001 broiler diets. Poult. Sci. 82:1500-1508.
19. Havenstein, G. B., P. R. Ferket, S. E. Scheidler, and B. T. Larson. 1994. Growth, livability, and feed conversion of 1957 and 1991 broilers when fed 'typical' 1957 versus 1991 broiler diets. Poult. Sci. 73:1785-1794.
20. Herrero, A., and G. Barja. 1998. Hydrogen peroxide production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved. Mech. Aging Dev. 103:133-146.
21. Herz, H., D. R. Blake, and M. Grootveld. 1997. Multicomponent investigations of the hydrogen peroxide- and hydroxyl radical-scavenging antioxidant capacities of biofluids: the roles of endogenous pyruvate and lactate. Relevance to inflammatory joint diseases. Free Radic. Res. 26:19-35.
22. Huntington, G. B., and B. W. McBride. 1988. Ruminant splanchnic tissues. Energy cost of absorption and metabolism. Pages 313-327 in Biomechanisms Regulating Growth and Development. G. L. Steffens and T. S. Rumsey, ed. Beltsville Symposia in Agricultural Research, Beltsville, MD.
23. Iqbal, M., D. Cawthon, R. F. Wideman, Jr., and W. G. Bottje. 2001. Lung mitochondrial dysfunction in pulmonary hypertension syndrome. I. Site-specific defects in electron transport chain. Poult. Sci. 80:485-495.
24. Iqbal, M., N. Pumford, K. Lassiter, Z. Tang, T. Wing, M. Cooper, and W. G. Bottje. 2004. Low feed efficient broilers within a single genetic line exhibit higher oxidative stress and protein expression in breast muscle with lower mitochondrial complex activity. Poult. Sci. 83:474-484.
25. Ji, L. L. 1999. Antioxidants and oxidative stress in exercise. Proc. Soc. Exp. Biol. Med. 222:283-292.
26. Ji, L. L., and E. W. Mitchell. 1994. Effects of adriamycin on heart mitochondrial function in rested and exercised rats. Biochem. Pharmacol. 47:877-885.
27. Koeppen, A. H., and K. M. Riley. 1987. Effect of free malonate on the utilization of glutamate by rat brain mitochondria. J. Neurochem. 48:1509-1515.
28. Kristal, B., S. Koopmans, C. T. Jackson, Y. Ikeno, B. Par, and B. P. Yu. 1997. Oxidant-mediated repression of mitochondrial transcription in diabetic rats. Free Radic. Biol. Med. 22:813-822.
29. Kwong, L. K., and R. S. Sohal. 1998. Substrate and site specificity of hydrogen peroxide generation in mouse mitochondria. Arch. Biochem. Biophys. 350:118-126.
30. Lawrence, C. B., and N. T. Davies. 1986. A novel, simple and rapid method for the isolation of mitochondria which exhibit respiratory control from rat small intestinal mucosa. Biochim. Biophys. Acta 848:35-40.
31. Lehninger, A. L., D. L. Nelson, and M. M. Cox. 1993. Principles of Biochemistry. 2nd ed. Worth Publishers, New York.
32. Lutz, R. T., and T. S. Stahly. 2003. Quantitative relationship between mitochondrial bioenergetics and efficiency of animal growth. J. Anim. Sci. 81(Suppl. 1):141. (Abstr.)
33. Madesh, M., A. Ramachandran, A. Pulimood, M. Vadranam, and K. A. Balusubramanian. 2000. Attenuation of intestinal ischemia/reperfusion injury with sodium nitroprusside: studies on mitochondrial function and lipid changes. Biochim. Biophys. Acta 1500:204-216.
34. McBride, B. W., and J. M. Kelly. 1990. Energy cost of absorption and metabolism in the ruminant gastrointestinal tract and liver. A review. J. Anim. Sci. 68:2997-3010.
35. Miwa, H., J. Fujii, H. Kanno, N. Taniguchi, and K. Aozasa. 2000. Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death. Free Radic. Res. 33:45-56.
36. Mukherjee, T. K., R. W. C. Stevens, and M. P. Hoogendoorn. 1970. Oxygen uptake of mitochondrial isolates from two breeds of chickens and their F1 cross. Poult. Sci. 49:1130-1131.
37. Nohl, H., L. Gille, K. Schonheit, and Y. Liu. 1996. Conditions allowing redox-cycling of ubisemiquinone in mitochondria to establish a direct redox couple with molecular oxygen. Free Radic. Biol. Med. 20:207-213.
38. Renner, R., S. M. Innis, and M. T. Clandinin. 1979. Effects of high and low erucic acid rapeseed oils on energy metabolism and mitochondrial function of the chick. J. Nutr. 109:378-387.
39. Rota, C. C., C. F. Chignell, and R. P. Mason. 1999. Evidence for free radical formation during the oxidation of 2′-7′-dichlorofluorescin to the fluorescent dye 2′-7′- dichlorofluorescein by horseradish peroxidase: Possible implications for oxidative stress measurements. Free Radic. Biol. Med. 27:873-881.
40. Rustin, P., and A. Rotig. 2001. Inborn errors of complex II - Unusual human mitochondrial diseases. Biochim. Biophys. Acta 1553:117-122.
41. Shigenaga, M. K., T. M. Hagen, and B. N. Ames. 1994. Oxidative damage and mitochondrial decay in aging. Proc. Natl. Acad. Sci. USA 91:10771-10778.
42. Simon, H. U., A. Haj-Yehia, and F. Levi-Schaffer. 2000. Role of reactive oxygen species in apoptosis induction. Apoptosis 5:415-418.
43. Spratt, R. S., B. W. McBride, H. S. Bayley, and S. Leeson. 1990. Energy metabolism of broiler breeder hens. 2. Contribution of tissues to total heat production in fed and fasted hens. Poult. Sci. 69:1348-1356.
44. Srere, P. A. 1969. Citrate synthase. Methods Enzymol. 13:3-26.
45. Tang, Z., M. Iqbal, D. Cawthon, and W. Bottje. 2000. Defects in heart and breast muscle mitochondrial electron transport of broilers with pulmonary hypertension syndrome. Free Radic. Biol. Med. 29:S25.
46. Tang, Z., M. Iqbal, D. Cawthon, and W. Bottje. 2002. Heart and breast muscle mitochondrial dysfunction in pulmonary hypertension in broilers (Gallus domesticus). Comp. Biochem. Physiol. 132:527-540.
47. Toyomizu, M., D. Kirihara, M. Tanaka, K. Hayashi, and Y. Tomita. 1992a. Dietary protein level alters oxidative phosphorylation in heart and liver mitochondria of chicks. Brit. J. Nutr. 68:89-99.
48. Toyomizu, M., K. Mehara, T. Kamada, and Y. Tomita. 1992b. Effects of various fat sources on growth and hepatic mitochondrial function in mice. Comp. Biochem. Physiol. 101A:613-618.
49. Turrens, J. F., and A. Boveris. 1980. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem. J. 191:421-427.
50. Webster, A. J. L. 1980. Energy cost of digestion and metabolism in the gut. Pages 469-84 in Digestive Physiology and Metabolism in Ruminants. Y. Ruckebusch and P. Thivend, ed. MTP Press, Lancaster, UK.
51. Wei, Y. H., C. F. Lee, H. C. Lee, Y. S. Ma, C. W. Wang, C. Y. Lu, and C. Y. Pang. 2001. Increases of mitochondrial mass and mitochondrial genome in association with enhanced oxidative stress in human cells harboring 4,977 BP-deleted mitochondrial DNA. Ann. NY Acad. Sci. 928:97-112.
52. Yen, J., J. Nienaber, D. Hill, and W. Pond. 1989. Oxygen consumption by portal vein-drained organs and by whole animal in conscious growing swine. Proc. Soc. Exp. Biol. Med. 190:393-398.
53. Yu, B. P. 1994. Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 74:139-162.