Levamisole in steroid-sensitive nephrotic syndrome children with frequent relapses and/or steroid dependency: Comparison of daily and every-other-day usage

Nephron - Clinical Practice

Volumn 97, Issue 4, 2004, Pages

  Fu, Lin Shien ^a   Shien, Chao Yan ^a   Chi, Ching Shiang ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Levamisole; Steroid dependency; Steroid sensitive nephrotic syndrome

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; LEVAMISOLE; PREDNISOLONE; STEROID;

ADOLESCENT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG USE; FEMALE; FOLLOW UP; HUMAN; LEUKOCYTE COUNT; LEUKOPENIA; MALE; NEPHROTIC SYNDROME; PRESCHOOL CHILD; PRIORITY JOURNAL; RELAPSE; REMISSION; SCHOOL CHILD; STATISTICAL SIGNIFICANCE; SURVIVAL RATE; UREA NITROGEN BLOOD LEVEL;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DISEASE-FREE SURVIVAL; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOLOGIC FACTORS; KIDNEY FUNCTION TESTS; LEUKOPENIA; LEVAMISOLE; LIFE TABLES; LIVER FUNCTION TESTS; MALE; NEPHROTIC SYNDROME; PREDNISOLONE; RECURRENCE; REMISSION INDUCTION; TREATMENT OUTCOME;

EID: 4444359227     PISSN: 16602110     EISSN: None     Source Type: Journal    
DOI: 10.1159/000079172     Document Type: Article

References (17)

1. Barratt TM, Beattie JM, Coleman J, et al: Consensus statement on management and audit potential for steroid responsive nephrotic syndrome. Arch Dis Child 1994;70:151-157.
2. Siegel NJ, Goldberg H, Krassner LS, Hayslett JP: Long-term follow-up of children with steroid-responsive nephrotic syndrome. J Pediatr 1972;81:251-258.
3. Neuhaus TJ, Fay J, Dillon MJ, Trompeter RS, Barratt TM: Alternative treatment to corticosteroids in steroid sensitive idiopathic nephrotic syndrome. Arch Dis Child 1994;71:522-526.
4. Dayal U, Dayal AK, Shastry JC, Raghupathy P: Use of levamisole in maintaining remission in steroid-sensitive nephrotic syndrome. Nephron 1994;66:408-412.
5. Tenbrock K, Muller-Berghaus J, Fuchshuber A, Michalk D, Querfeld U: Levamisole treatment in steroid-sensitive and steroid-resistant nephrotic syndrome. Pediatr Nephrol 1998;12:459-462.
6. Bagga A, Sharma A, Srivastava RN: Levamisole therapy in corticosteroid-dependent nephrotic syndrome. Pediatr Nephrol 1997;11:415-417.
7. Donia AF, Amer GM, Ahmed HA, Gazareen SH, Moustafa FE, Shoeib AA, et al: Levamisole: Adjunctive therapy in steroid dependent minimal change nephrotic children. Pediatr Nephrol 2002;17:355-358.
8. Durkan AM, Hodson EM, Willis NS, Graig JC: Immunosuppressive agents in childhood nephrotic syndrome: A meta-analysis of randomized controlled trials. Kidney Int 2001;59:1919-1927.
9. La Manna A, Polito C, Del Gando R, Foglia AC: Levamisole in children's idiopathic nephrotic syndrome. Child Nephrol Urol 1988;9:200-202.
10. British Association for Paediatric Nephrology: Levamisole for corticosteroid-dependent nephrotic syndrome in childhood. Lancet 1991;337:1555-1557.
11. Amery WK, Gough DA: Levamisole and immunotherapy: Some theoretic and practical considerations and their relevance to human disease. Oncology 1981;38:168-181.
12. Bulugahapitiya DT: Liver toxicity in a nephrotic patient treated with levamisole (letter). Arch Dis Child 1997;76:289.
13. Powell J, Grech H, Holder J: A boy with cutaneous necrosis occurring during treatment of levamisole. Clin and Exp Dermatol 2002;27:32-33.
14. Bagga A, Hari P: Levamisole-induced vasculitis. Pediatr Nephrol 2000;14:1057-1058.
15. Menni S, Pistritto G, Gianotti R, Ghio L, Edefonti A: Ear lobe bilateral necrosis by levamisole-induced occlusive vasculitis in a pediatric patient. Pediatr Dermatol 1997;14:477-479.
16. Barbano G, Ginervi F, Ghiggeri GM, Gusmano R: Disseminated autoimmune disease during levamisole treatment of nephrotic syndrome. Pediatr Nephrol 1999;13:602-603.
17. Mackie FE, Roy LP, Stevens M: Onset of leukemia after levamisole treatment for nephrotic syndrome. Pediatr Nephrol 1994;8:527-528.