HPLC determination of dexamethasone in human plasma

Journal of Liquid Chromatography and Related Technologies

Volumn 27, Issue 14, 2004, Pages 2293-2306

  Song, Yun Kyoung ^a   Park, Jeong Sook ^a   Kim, Jin Ki ^a   Kim, Chong Kook ^a  

^a Seoul National University   (South Korea)

Author keywords

Bioavailability; Dexamethasone; HPLC; Human plasma

Indexed keywords

CLONING; CONCENTRATION (PROCESS); LIQUID CHROMATOGRAPHY; MONITORING; ULTRAVIOLET DETECTORS;

HUMAN PLASMA; MOBILE PHASE; SUPERCLONES;

BIOTECHNOLOGY;

ACETIC ACID ETHYL ESTER; ACETONITRILE; BUFFER; DESOXIMETASONE; DEXAMETHASONE; PHOSPHATE;

ACCURACY; ANALYTIC METHOD; ANALYTICAL EQUIPMENT; ANALYZER; ARTICLE; BLOOD SAMPLING; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ANALYSIS; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ISOLATION; DRUG STRUCTURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SEPARATION TECHNIQUE; ULTRAVIOLET SPECTROSCOPY;

EID: 4444349226     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-200025726     Document Type: Article

References (19)

1. Chrousos, O.P.; Murgioris, A.N. Adrenocorticosteroids and adrenocortical antagonists. In Basic & Clinical Pharmacology, 8th Ed.; Katzung, E.G., Ed.; McGraw-Hill: New York, 2000; 660-678.
2. Schild, P.N.; Charles, B.G. Determination of dexamethasone in plasma of premature neonates using high performance liquid chromatography. J. Chromatogr. B 1994, 658, 189-192.
3. Volin, P. High performance liquid Chromatographic analysis of corticosteroids. J. Chromatogr. B 1995, 671, 319-340.
4. Courtheyn, D.; Vercammen, J.; Logghe, M.; Seghers, H.; De Wasch, K.; De Brabander, H. Determination of betamethasone and triamcinolone acetonide by GC-NCI-MS in excreta of treated animals and development of a fast oxidation procedure for derivatisation of corticosteroids. Analyst 1998, 723 (12), 2409-2414.
5. Stoiker, A.A.M.; Schwillens, P.L.W.J.; van Ginkel, L.A.; Brinkman, U.A.Th. Comparison of different liquid chromatography methods for the determination of corticosteroids in biological matrices. J. Chromatogr. A 2000, 893, 55-67.
6. Sheran, P.; O'Keeffe, M.; Smyth, M.R. Reversed-phase high performance liquid Chromatographic determination of dexamethasone in bovine tissues. Analyst 1991, 116 (12), 1365-1368.
7. Santos-Montes, A.; Gasco-Lopez, R.; Izquierdo Hornillos, R.; Gonzalo-Lumbreras, R. Solvent and solid-phase extraction of natural and synthetic corticoids in human urine. J. Chromatogr. A 1994, 652 (1), 83-89.
8. Katayama, M.; Masuda, Y.; Taniguchi, H. Determination of corticosteroids in plasma by high-performance liquid chromatography after pre-column derivatization with 2-(4-carboxyphenyl)-5,6-dimethyibenzi-midazole. J. Chromatogr. Biomed. Appl. 1993, 672, 33-39.
9. Fluri, K.; Rivier, L.; Dience-Nagy, A.; You, C.; Maître, A.; Schweizer, C.; Saugy, M.; Mangin, P. Method for confirmation of synthetic cortocosteroids in doping urine samples by liquid chromatography-electrospray ionisation mass spectrometry. J. Chromatogr. A 2001, 926, 87-95.
10. Cirimele, V.; Kintz, P.; Dumestre, V.; Goullé, J.P.; Ludes, B. Identification of ten corticosteroids in human hair by liquid chromatography - ionspray mass spectrometry. Forensic Sci. Int. 2000, 107, 381-388.
11. Yap, B.K.; Johnston, G.A.; Kazlauskas, R. Routine screening and quantitation of urinary corticosteroids using bench-top gas chromatography-mass- selective detection. J. Chromatogr. 1992, 573 (2), 183-190.
12. Rivero-Marabé, J.J.; Maynar-Mariño, J.I.; García-de-Tiedra, M.P.; Galán-Martín, A.M.; Caballero-Loscos, M.J.; Maynar-Mariño, M. Determination of natural corticosteroids in urine samples from sportsmen. J. Chromatogr. B 2001, 767, 77-84.
13. Schoneshofer, M.; Fenner, A.; Dulce, H.J. Interferences in the radioimmunological determination of urinary free cortisol. Clin. Chim. Acta 1980, 707 (1), 125-134.
14. Murphy, B.E.; Okouneff, L.M.; Klein, O.P.; Ngo, S.C. Lack of specificity of cortisol determinations in human urine. J. Clin. Endocrinol. Metab. 1981, 53 (1), 91-99.
15. McConway, M.G.; Chapman, R.S. Development and evaluation of a simple, direct, solid-phase radioimmunoassay of serum cortisol from readily available reagents. Clin. Chim. Acta 1986, 158 (1), 59-70.
16. Hughes, D.; Murphy, J.F.; Dyas, J.; Robinson, J.A.; Raid-Fahmy, D.; Hughes, I.A. Blood spot glucocorticoid concentrations in ill preterm infants. Arch. Dis. Child. 1987, 62 (10), 1014-1018.
17. Lee, Y.J.; Kim, Y.G.; Lee, M.G.; Chung, S.J.; Lee, M.H.; Shim, C.K. Analysis of bioequivalence study using log-transformed model. Yakhakhoeji 2000, 44 (4), 308-314.
18. Park, J.S.; Park, K.M.; Kim, C.K. Determination of triflusal in human plasma by high performance liquid chromatography with automated column switching system. J. Liq. Chrom. Rel. Technol. 2000, 23 (16), 2513-2524.
19. Kovarik, J.M.; Purba, H.S.; Pongowski, M.; Gerbeau, C.; Humbert, H.; Mueller, E.A. Pharmacokinetics of dexamethasone and valspodar, a P-glycoprotein (mdr1) modulator: implications for coadministration. Pharmacotherapy 1998, 18, 1230-1236.