A new antimicrobial dibenzofuran Sch 725421 from an unidentified fungus

Journal of Antibiotics

Volumn 57, Issue 7, 2004, Pages 465-467

  Yang, Shu Wei ^a   Chan, Tze Ming ^a   Patel, Reena ^a   Terracciano, Joseph ^a   Loebenberg, David ^a   Patel, Mahesh ^a   Chu, Min ^a,b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b CUBIST PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DIBENZOFURAN DERIVATIVE; SCH 725421; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; BACTERIAL STRAIN; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CORRELATION COEFFICIENT; CULTURE MEDIUM; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; FUNGAL STRAIN; FUNGUS CULTURE; FUNGUS IDENTIFICATION; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID PHASE EXTRACTION; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 4444343937     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.57.465     Document Type: Note

References (13)

1. Yang, S.-W.; T.-M. Chan, S. A. Pomponi, G. Chen, D. Loebenberg, A. Wright, M. Patel, V. Gullo, B. Pramanik & M. Chu: Structure elucidation of a new antifungal sterol sulfate, Sch 575867, from a deep-water marine sponge (Family: Astroscleridae). J. Antibiotics 56: 186-189, 2003
2. Yang, S.-W.; A. Buevich, T.-M. Chan, J. Terracciano, G. Chen, D. Loebenberg, M. Patel, E. Boehm, V. Gullo, B. Pramanik & M. Chu: A new antifungal sterol sulfate, Sch 601324, from Chrysosporium sp. J. Antibiotics 56: 419-422, 2003
3. Yang, S.-W.; T.-M. Chan, S. A. Pomponi, W. Gonsiorek, G. Chen, A. E. Wright, W. Hipkin, M. Patel, V. Gullo, B. Pramanik, P. Zavodny & M. Chu: A new sesterterpene, Sch 599473, from a marine sponge, Ircinia sp. J. Antibiotics 56: 783-786, 2003
4. Yang, S.-W.; T.-M. Chan, S. A. Pomponi, G. Chen, A. E. Wright, M. Patel, V. Gullo, B. Pramanik & M. Chu: A new bicyclic guanidine alkaloid, Sch 575948, from a marine sponge, Ptilocaulis spiculifer. J. Antibiotics 56: 970-972, 2003
5. Tanahashi, T.; Y. Takenaka, N. Nagakura & N. Hamada: Dibenzofurans from the cultured lichen mycobionts of Lecanora cinereocarnea. Phytochemistry 58: 1129-1134, 2001
6. Huneck, S.; J. A. Elix, R. Naidu & G. Follmann: 3-O-Demethylschizopeltic acid, a new dibenzofuran from the lichen Roccella hypomecha. Aust. J. Chem. 46: 407-410, 1993
7. Elix, J. A.; D. A. Venables, T. Lumbsch & L. Brako: Further new metabolites from lichens. Aust. J. Chem. 47: 1619-1623, 1994
8. Elix, J. A.; D. A. Venables & M. Wedin: New dibenzofurans and depsides from the lichen Bunodophoron patagonicum. Aust. J. Chem. 47: 1335-1344, 1994
9. Shibata, S. & Y. Iitaka: Renewed studies on the structure of didymic acid. Chem. Pharm. Bull. 32: 366-368, 1984
10. Sawada, T.; M. Aono, S. Asakawa, A. Ito & K. Awano: Structure determination and total synthesis of a novel antibacterial substance, AB0022A, produced by a cellular slime mold. J. Antibiotics 53: 959-966, 2000
11. Igboechi, C. A.; R. T. Parfitt & M. G. Rowan: Two dibenzofuran derivatives from fruits of Rhodomyrtus macrocarpa. Phytochemistry 23: 1139-1141, 1984
12. Carotenuto, A.; E. Fattorusso, V. Lanzotti & S. Magno: Porric acids A-C - new antifungal dibenzofurans from the bulbs of Allium Porrum L. Eur. J. Org. Chem. 661-663, 1998
13. Ito, C.; Y. Miyamoto, K. S. Rao & H. Furukawa: A novel dibenzofuran and two new xanthones from Calophyllum panciflorum. Chem. Pharm. Bull. 44: 441-443, 1996