Nε-(Carboxymethyl)lysine depositions in human aortic heart valves: Similarities with atherosclerotic blood vessels

Atherosclerosis

Volumn 174, Issue 2, 2004, Pages 287-292

  Baidoshvili, Alexi ^a,b   Niessen, Hans W M ^a,b   Stooker, Wim ^a,b   Huybregts, Rien A J M ^a   Hack, C Erik ^a,b,c   Rauwerda, Jan A ^a,b   Meijer, Chris J L M ^a   Eijsman, Leon ^a   Van Hinsbergh, Victor W M ^a,b,d   Schalkwijk, Casper G ^a,b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c SANQUIN RESEARCH   (Netherlands)

^d TNO   (Netherlands)

Author keywords

Advanced glycation end product; Atherosclerosis; Heart valve; Immunohistochemistry

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ADVANCED GLYCATION END PRODUCT; BIOLOGICAL MARKER; DRUG DERIVATIVE; LYSINE; N(6) CARBOXYMETHYLLYSINE; N(6)-CARBOXYMETHYLLYSINE;

ADULT; AGED; AORTA VALVE; AORTA VALVE STENOSIS; ARTICLE; ATHEROSCLEROSIS; AUTOPSY; BIOACCUMULATION; BLOOD VESSEL; CALCIFICATION; CHILDHOOD; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATION; ENDOTHELIUM; FIBROBLAST; HEART SURGERY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIPID STORAGE; MACROPHAGE; MITRAL VALVE; PRIORITY JOURNAL; RHEUMATIC FEVER; VASCULAR TISSUE; ARTERIOSCLEROSIS; CADAVER; COMPARATIVE STUDY; CULTURE TECHNIQUE; FEMALE; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; PROBABILITY; REFERENCE VALUE; VASCULAR ENDOTHELIUM;

ADULT; AGED; AGED, 80 AND OVER; AORTIC VALVE; ARTERIOSCLEROSIS; BIOLOGICAL MARKERS; BLOOD VESSELS; CADAVER; CULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; FEMALE; FIBROBLASTS; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; IMMUNOHISTOCHEMISTRY; LYSINE; MALE; MIDDLE AGED; MITRAL VALVE; PROBABILITY; REFERENCE VALUES;

EID: 4444340011     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2004.02.012     Document Type: Article

References (35)

1. Otto C.M., Kuusisto J., Reichenbach D.D., Gown A.M., O'Brien K.D. Characterization of the early lesion of 'degenerative' valvular aortic stenosis: histologic and immunohistochemical studies. Circulation. 90:1994;844-853
2. Olsson M., Rosenqvist M., Nilsson J. Expression of HLA-DR antigen and smooth muscle cell differentiation markers by valvular fibroblasts in degenerative aortic stenosis. J. Am. Coll. Cardiol. 24:1994;1664-1671
3. Olsson M., Dalsgaard C.J., Haegerstrand A., et al. Accumulation of T lymfocytes and expression of interleukin-2 receptors in non-rheumatic stenotic aortic valves. J. Am. Coll. Cardiol. 23:1994;1162-1170
4. Gillies P.J., Robinson C.S., Cockrell B.Y., Graepel G.J. Effect of lanthanum chloride on established atherosclerosis in the cholesterol-fed rabbit. Mitral valve as a site for assessment of treatment effects. Arteriosclerosis. 9:1989;253-260
5. Thubrikar M.J., Deck J.D., Aouad J., Chen J.M. Intramural stress as a causative factor in atherosclerotic lesions of the aortic valve. Atherosclerosis. 55:1985;299-311
6. Dellgren G., Feindel C.M., Bos J., Ivanov J., David T.E. Aortic valve replacement with the Toronto SPV: long-term clinical and hemodynamic results. Eur. J. Cardiothorac. Surg. 21:2002;698-702
7. Skowasch D., Schrempf S., Lentini S., et al. Chlamydia pneumoniae and cytomegalovirus in degenerative aortic valve stenoses. Z. Kardiol. 91:2002;290-296
8. Robicsek F., Thubrikar M.J. Etiology of degenerative disease of the tri-leaflet aortic valve: a simple explanation for a complex problem. Z. Kardiol. 90:2001;35-38
9. Robicsek F., Thubrikar M.J., Fokin A.A. Cause of degenerative disease of the tri-leaflet aortic valve: review of subject and presentation of a new theory. Ann. Thorac. Surg. 73:2002;1346-1354
10. Nakamura Y., Horii Y., Nishino T., et al. Immunohistochemical localization of advanced glycation end products in coronary atheroma and cardiac tissue in diabetes mellitus. Am. J. Pathol. 143:1993;1649-1656
11. Makita Z., Vlassara H., Cerami A., Bucala R. Immunochemical detection of advanced glycosylation end products in vivo. J. Biol. Chem. 267:1992;5133-5138
12. Araki N., Ueno N., Chakrabarti B., Morino Y., Horiuchi S. Immunochemical evidence for the presence of advanced glycation end products in human lens proteins and its positive correlation with aging. J. Biol. Chem. 267:1992;10211-10214
13. Nakayama H., Mitsuhashi T., Kuwajima S., et al. Immunochemical detection of advanced glycation end products in lens crystallins form streptozocin-induced diabetic rats. Diabetes. 42:1993;345-350
14. Mitsuhashi T., Nakayama H., Itoh T., et al. Immunochemical detection of advanced glycation end products in renal cortex from STZ-induced diabetic rat. Diabetes. 42:1993;826-832
15. Baynes T.W., Monnier V.M. The Maillard reaction in aging, diabetes and nutrition. Prog. Clin. Biol. Res. 304:1989;400-410
16. Baynes J.W. Role of oxidative stress in development of complications in diabetes. Diabetes. 40:1991;405-412
17. ε- (carbocymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation. J. Clin. Invest. 104:1999;103-113
18. ε-(carboxymethyl)lysine in human tissues in diabetes and aging. J. Clin. Invest. 99:1997;457-468
19. Sakata N., Imanaga Y., Meng J., et al. Immunohistochemical localization of different epitopes of advanced glycation end products in human atherosclerotic lesions. Atherosclerosis. 141:1998;61-75
20. ε-carboxymethyl)lysine in atherosclerotic vascular lesions as a marker for local oxidative stress. Atherosclerosis. 144:1999;41-47
21. ε- (carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody. Biochim Biophys Acta 2004, in press.
22. ε-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry. Lab. Invest. 82:2002;795-808
23. ε-(carboxymethyl)lysine in lens proteins. Biochemistry. 28:1989;9464-9468
24. Glomb M.A., Monnier V.M. Mechanism of protein modification by glyoxal and glycoladehyde, reactive intermediates of the Maillard reaction. J. Biol. Chem. 270:1995;10017-10026
25. ε-(carboxymethyl)lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite. Diabetes. 51:2002;2833-2839
26. Wells-Knecht K.J., Zyzak D.V., Litchfield J.E., Thorpe S.R., Baynes J.W. Mechanism of autooxidative glycosylation: identification of glyoxal and arabinose as intermediates in the autooxidative modification of proteins by glucose. Biochemistry. 21:1995;3702-3709
27. ε-(carboxymethyl)hydroxylysine in human skin collagen. Biochemistry. 30:1991;1205-1210
28. ε-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions. J. Biol. Chem. 271:1996;9982-9986
29. ε- (carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation. J. Clin. Invest. 104:1999;103-113
30. Muller A.M., Cronen C., Kupferwasser L.I., et al. Expression of endothelial cell adhesion molecules on heart upregulation in degeneration as well as acute endocarditis. J. Pathol. 191:2000;54-60
31. Hanada T., Hashimoto M., Nosaka K., et al. Shear stress enhances prostacyclin release from endocardial endothelial cells. Life Sci. 66:2000;215-220
32. Kume S., Takeya M., Mori T., et al. Immunohistochemical and ultrastructural detection of advanced glycation end products in the atherosclerotic lesions of human aorta with a novel specific antibody. Am. J. Pathol. 147:1995;654-667
33. ε-(carboxymethyl) lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signalling pathways and modulate gene expression. J. Biol. Chem. 274:1999;31740-31749
34. Schmidt A.M., Yan S.D., Stern D.M. The dark side of glucose. Nat Med. 1:1995;1002-1004
35. Olsson M., Thyberg J., Nilsson J. Presence of oxidized low density lipoprotein in non-rheumatic stenotic aortic valves. Arterioscler. Thromb. Vasc. Biol. 19:1999;1218-1222