Paclitaxel-loaded poly(L-lactic acid) microspheres 3: Blending low and high molecular weight polymers to control morphology and drug release

International Journal of Pharmaceutics

Volumn 282, Issue 1-2, 2004, Pages 61-71

  Liggins, Richard T ^a,b   Burt, Helen M ^b  

^a Angiotech Pharmaceuticals Inc   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Drug release; Microsphere; Paclitaxel; PLLA; Polymer blending; Thermal properties

Indexed keywords

MICROSPHERE; PACLITAXEL; POLYLACTIC ACID; POLYMER;

ARTICLE; CONTROLLED DRUG RELEASE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STRUCTURE; DRUG SYNTHESIS; GLASS TRANSITION TEMPERATURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MELTING POINT; MOLECULAR WEIGHT; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE; THERMAL ANALYSIS;

ALGORITHMS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; INJECTIONS, INTRAPERITONEAL; LACTIC ACID; MICROSPHERES; MOLECULAR WEIGHT; PACLITAXEL; PARTICLE SIZE; POLYMERS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 4444322648     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2004.05.026     Document Type: Article

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