Genetic analysis of APOAV polymorphisms (T-1131/C, Ser19/Trp and Val153/Met): No effect on plasma remnant particles concentrations

Clinica Chimica Acta

Volumn 348, Issue 1-2, 2004, Pages 171-175

  Hubacek, Jaroslav A ^a,b   Kovář, Jan ^a,b   Škodová, Zdena ^a   Pit'ha, Jan ^a   Lánská, Věra ^a   Poledne, Rudolf ^a,b  

^a INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

^b Ctr for Exp Cardiovasc Research   (Czech Republic)

Author keywords

Apolipoprotein AV; Genetic; Polymorphism; Remnant particles; Triglyceride

Indexed keywords

APOLIPOPROTEIN A5; CYSTEINE; LIPOPROTEIN; PROTEIN SUBUNIT; SERINE; THREONINE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VALINE;

ADULT; AGED; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; LIPID BLOOD LEVEL; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION MAPPING;

ADULT; APOLIPOPROTEINS; APOLIPOPROTEINS A; CHOLESTEROL; COHORT STUDIES; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LIPOPROTEINS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; TRIGLYCERIDES;

EID: 4444321228     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2004.05.011     Document Type: Article

References (18)

1. Hodis H.N. Triglyceride-rich lipoprotein remnant particles and risk of atherosclerosis. Circulation. 99:1999;2852-2854
2. Kugiyama K., Doi H., Takazoe K., et al. Remnant lipoprotein levels in fasting serum predict coronary events in patients with coronary artery disease. Circulation. 99:1999;2858-2860
3. Nakajima K., Saito T., Tamura A., et al. Cholesterol in remnant-like lipoproteins in human serum using monoclonal anti apoB-100 and anti apoA-I immunoaffinity mixed gels. Clin. Chim. Acta. 223:1993;53-71
4. Waterworth D.M., Hubacek J.A., Pitha J., et al. Plasma levels of remnant particles are determined in part by variation in the APOC3 gene response element and the APOCI-APOE cluster. J. Lipid Res. 41:2000;1103-1109
5. Pennacchio L.A., Olivier M., Hubacek J.A., et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science. 294:2001;169-173
6. Šeda O., Šedová L. New apoliprotein A-V: comparative genomics meets metabolism. Physiol. Res. 52:2003;141-146
7. Kao J.T., Wen H.C., Chien K.L., Hsu H.C., Lin S.W. A novel genetic variant in the apolipoprotein A5 is associated with hypertriglyceridemia. Hum. Mol. Genet. 12:2003;2533-2539
8. Hubacek J.A., Adámková V., Češka R., Poledne R., Hořínek A., Vráblík M. New variants in the apolipoprotein AV gene in individuals with extreme triglyceride levels. Physiol. Res. 53:2004;225-228
9. Pennacchio L.A., Olivier M., Hubacek J.A., et al. Two independent apolipoprotein AV haplotypes influence human plasma triglyceride levels. Hum. Mol. Genet. 11:2002;3031-3038
10. Talmud P.J., Hawe E., Martin S., et al. Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum. Mol. Genet. 11:2002;3036-3039
11. Nabika T., Nasreen S., Kobayashi S., Masuda J. The genetic effect of the apoprotein AV gene on the serum triglyceride level in Japanese. Atherosclerosis. 16:2002;201-204
12. Horínek A., Vráblík M., Ceška R., Adamkova V., Poledne R., Hubacek J.A. T-1131→C polymorphism within the apolipoprotein AV gene in hypertriglyceridemic individuals. Atherosclerosis. 167:2003;369-370
13. Vrablik M., Horínek A., Češka R., Adamkova V., Poledne R., Hubacek J.A. Ser19→Trp polymorphism within the apolipoprotein AV gene in hypertriglyceridemic people. J. Med. Genet. 40:2003;e105
14. Hubacek J.A., Škodova Z., Adamkova V., Lanska V., Poledne R. The influence of APOAV polymorphisms (T-1131>C and S19>W) on plasma triglyceride levels and risk of myocardial infarction. Clin. Genet. 65:2004;126-130
15. Hubacek J.A., Škodova Z., Adamkova V., et al. APOAV polymorphisms (T-1131/C and Ser19/Trp) influence plasma triglyceride levels and risk of myocardial infarction. Exp. Clin. Cardiol. 8:2003;151-154
16. Hubacek J.A., Waterworth D.M., Pitha J., Humphries S.E., Talmud P.J., Poledne R. Polymorphisms in the lipoprotein lipase and hepatic lipase genes and plasma lipid values in Czech population. Physiol. Res. 50:2001;345-351
17. Hubacek J.A., Pitha J., Adámková V., Škodová Z., Lánská V., Poledne R. Apolipoprotein E and apolipoprotein CI polymorphisms in the Czech population. Almost complete linkage disequilibrium of the less frequent alleles of both polymorphisms. Physiol. Res. 52:2003;195-200
18. Szalai C., Keszei M., Duba J., et al. Polymorphism in the promoter region of the apolipoprotein A5 gene is associated with an increased susceptibility for coronary artery disease. Atherosclerosis. 173:2004;109-114