Fine structure of long-term changes in the cochlear nucleus after acoustic overstimulation: Chronic degeneration and new growth of synaptic endings

Journal of Neuroscience Research

Volumn 77, Issue 6, 2004, Pages 817-828

  Kim, J J ^a   Gross, J ^a   Potashner, S J ^a   Morest, D K ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Auditory system; Deafness; Neurodegenerative disease; Noise; Synaptic plasticity; Tinnitus

Indexed keywords

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY STIMULATION; CHINCHILLA; COCHLEAR NUCLEUS; CONTROLLED STUDY; ELECTRON MICROSCOPY; HEARING IMPAIRMENT; INTERNEURON; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVE FIBER DEGENERATION; NERVE GROWTH; NOISE INJURY; NONHUMAN; PRIORITY JOURNAL; SYNAPSE VESICLE; TINNITUS;

ACOUSTIC STIMULATION; ANIMALS; CHINCHILLA; COCHLEAR NUCLEUS; NERVE DEGENERATION; PRESYNAPTIC TERMINALS; TIME;

EID: 4444312421     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20212     Document Type: Article

References (18)

1. Adams RD, Victor M. 1977. Principles of neurology. New York: McGraw-Hill. p 818.
2. Bodian D. 1966. Development of fine structure of spinal cord in monkey fetuses. I. The motoneuron neuropil at the time of onset of reflex activity. Bull Johns Hopkins Hosp 119:129-149.
3. Bovolenta P, Mason C. 1987. Growth cone morphology varies with position in the developing mouse visual pathway from retina to first targets. J Neurosci 7:1447-1460.
4. Campbell G, Frost DO. 1988. Synaptic organization of anomalous retinal projections to the somatosensory and auditory thalamus: target-controlled morphogenesis of axon terminals and synaptic glomeruli. J Comp Neurol 272:383-408.
5. Ginzberg RD, Gilula NB. 1980. Synaptogenesis in the vestibular sensory epithelium of the chick embryo. J Neurocytol 9:405-425.
6. Jhaveri S, Morest DK. 1982. Sequential alterations of neuronal architecture in nucleus magnocellularis of the developing chicken: an electron microscope study. Neuroscience 7:855-870.
7. Kim JJ, Gross J, Potashner SJ, Morest DK. 2004a. Fine structure of degeneration in the cochlear nucleus of the chinchilla after acoustic overstimulation. J Neurosci Res 77:798-816.
8. Kim JJ, Gross J, Morest DK, Potashner SJ. 2004b. A quantitative study of degeneration and new growth of axons and synaptic endings in the chinchilla cochlear nucleus after acoustic overstimulation. J Neurosci Res 77:829-842.
9. Kim J, Morest DK, Bohne BA. 1997. Degeneration of axons in the brain stem of the chinchilla after auditory stimulation. Hearing Res 103:169-191.
10. Morest DK. 1968. The growth of synaptic endings in the mammalian brain: a study of the calyces of the trapezoid body. Z Anat Entwicklungsgesch 127:201-220.
11. Morest DK, Kim J, Potashner SJ, Bohne BA. 1998. Long-term degeneration in the cochlear nerve and cochlear nucleus of the adult chinchilla following acoustic overstimulation. Microsc Res Tech 41:205-216.
12. Peusner KD. 1981. An ultrastructural study of the development of synaptic endings in the nucleus vestibularis tangentialis of the chick embryo. Neuroscience 6:2335-2350.
13. Pfenninger KH, Maylié-Pfenninger MF, Friedman LB, Simkowitz P. 1984. Lectin labeling of sprouting neurons. III. Type-specific glycoconjugates on growth cones of different origin. Dev Biol 106:97-108.
14. Tennyson VM. 1970. The fine structure of the axon and growth cone of the dorsal root neuroblast of the rabbit embryo. J Cell Biol 44:62-79.
15. Vaughn JE. 1989. Fine structure of synaptogenesis in the vertebrate central nervous system. Synapse 3:255-285.
16. Vaughn JE, Sims TJ. 1978. Axonal growth cones and developing axonal collaterals form synaptic junctions in embryonic mouse spinal cord. J Neurocytol 7:337-363.
17. Westrum LE. 1975. Electron microscopy of synaptic structures in olfactory cortex of early postnatal rats. J Neurocytol 4:713-732.
18. Whitehead MC, Morest DK. 1985. The growth of cochlear fibers and the formation of their synaptic endings in the avian inner ear: a study with the electron microscope. Neuroscience 14:277-300.