A novel, rapid and sensitive heterotypic cell adhesion assay for CD2-CD58 interaction, and its application for testing inhibitory peptides

Journal of Immunological Methods

Volumn 291, Issue 1-2, 2004, Pages 39-49

  Liu, Jining ^a   Chow, Vincent T K ^a   Jois, Seetharama D S ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Caco 2 cells; CD2; CD58; E rosetting assay; Jurkat cells; Lymphocyte epithelial adhesion assay

Indexed keywords

CD2 ANTIGEN; FLUORESCENT DYE; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; PEPTIDE; SODIUM HYDROXIDE;

ARTICLE; CELL ADHESION; CELL ASSAY; CELL LABELING; CELL SURFACE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; TECHNIQUE; TEMPERATURE DEPENDENCE;

ANTIGENS, CD2; ANTIGENS, CD58; BIOLOGICAL ASSAY; CACO-2 CELLS; CELL ADHESION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INTERFERON TYPE II; JURKAT CELLS; LYMPHOCYTES; PEPTIDES; PHYTOHEMAGGLUTININS; PROTEIN BINDING; SENSITIVITY AND SPECIFICITY; TETRADECANOYLPHORBOL ACETATE; TIME FACTORS;

EID: 4444297119     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.04.026     Document Type: Article

References (41)

1. Aiuti F., Rocchi G., D'Amelio R., Giunta S., Fiorilli M. Lymphoid cells in infectious mononucleosis classified according to T and B cell markers. Int. Arch. Allergy Appl. Immunol. 48:1975;353
2. Aruffo A., Hollenbaugh D. Therapeutic intervention with inhibitors of co-stimulatory pathways in autoimmune disease. Curr. Opin. Immunol. 13:2001;683
3. Arulanandam A.R.N., Withka J.M., Wyss D.F. The CD58 (LFA-3) binding site is a localized and highly charged surface area on the AGFCC′C face of the human CD2 adhesion domain. Proc. Natl. Acad. Sci. U. S. A. 90:1993;11613
4. Bachmann M.F., Barner M., Kopf M. CD2 sets quantitative thresholds in T cell activation. J. Exp. Med. 190:1999;1383
5. Bland P.W., Warren L.G. Antigen presentation by epithelial cells of the rat small intestine: I. Kinetics, antigen specificity and blocking by anti-Ia antisera. Immunology. 58:1986;1
6. Branco L., Barren P., Mao S.Y., Pfarr D., Kaplon R., Psotema C., Langermann S., Koenig S., Johnson S. Selective deletion of antigen-specific, activated T cells by a humanized mAb to CD2 (MEDI-507) is mediated by NK cells. Transplantation. 68:1999;1588
7. Bloemen P.G., van den Tweel M.C., Henricks P.A., Engels F., Wagenaar S.S., Rutten A.A., Nijkamp F.P. Expression and modulation of adhesion molecules on human brachial epithelial cells. Am. J. Respir. Cell. Mol. Biol. 9:1993;586
8. Cunningham A.C., Kirby J.A. Regulation and function of adhesion molecule expression by human alveolar epithelial cells. Immunology. 86:1995;279
9. Davis S.J., Ikemizu S., Wild M.K., van der Merwe P.A. CD2 and the nature of protein interactions mediating cell-cell recognition. Immunol. Rev. 163:1998;217
10. Dustin M.L., Selvaraj P., Mattaliano R.J., Springer T.A. Anchoring mechanisms for LFA-3 cell adhesion glycoprotein at membrane surface. Nature. 329:1987;846
11. Gines S., Marino M., Mallol J., Canela E.I., Morimoto C., Callebaut C., Hovanessian A., Casado V., Lluis C., Franco R. Regulation of epithelial and lymphocyte cell adhesion by adenosine deaminase-CD26 interaction. Biochem. J. 15:2002;203
12. Hershberg R.M., Framson P.E., Cho D.H., Lee L.Y., Kovats S., Beitz J., Blum J.S., Nepom G.T. Intestinal epithelial cells utilize two distinct pathways for HLA class II antigen processing. J. Clin. Invest. 100:1997;204
13. Hirahara H., Tsuchida M., Wanatabe T., Haga M., Matsumoto Y., Abo T., Eguchi S. Long-term survival of cardiac allografts in rats treated before and after surgery with monoclonal antibody to CD2. Transplantation. 59:1995;85
14. Hollo Z., Homolya L., Davis C.W., Sarkadi B. Calcein accumulation as a fluorometric functional assay of the multidrug transporter. Biochim. Biophys. Acta. 1191:1994;384
15. Homoloya L., Hollo Z., Germann U.A., Pastan I., Gottesmann M.M., Sarkadi B. Fluorescent cellular indicators are extruded by the multidrug resistance protein. J. Biol. Chem. 268:1993;21493
16. Hughes C.C., Savage C.O., Pober J.S. Endothelial cells augment T cell interleukin 2 production by a contact-dependent mechanism involving CD2/LFA-3 interaction. J. Exp. Med. 171:1990;1453
17. Iwata M., Sawada S., Sawa M., Thoft R.A. Mechanisms of lymphocyte adhesion to cultured human corneal epithelial cells. Curr. Eye Res. 16:1997;751
18. Kaiserlian D., Vidal K., Revillard J.P. Murine enterocytes can present soluble antigen to specific class II-restricted CD4+ T cells. Eur. J. Immunol. 19:1989;1513
19. Kaplon R.J., Hochman P.S., Michler R.E., Kwiatkowski P.A., Edwards N.M., Berger C.L., Xu H., Meier W., Wallner B.P., Chisholm P., Marboe C.C. Short course single agent therapy with an LFA-3-IgG1 fusion protein prolongs primate cardiac allograft survival. Transplantation. 61:1995;356
20. Kelly V.R., Singer G.G. The antigen presentation functions of renal tubular epithelial cells. Exp. Nephrol. 1:1993;102
21. Kim M., Sun Z.Y., Byron O., Campbell G., Wagner G., Wang J., Reinherz E.L. Molecular dissection of the CD2-CD58 counter-receptor interface identifies CD2 Tyr86 and CD58 Lys34 residues as the functional "hot spot" J. Mol. Biol. 314:2001;331
22. Lenschow D.J., Walunas T.L., Bluestone J.A. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:1996;233
23. Liversidge J., Dawson R., Hoey S., Mckay D., Grabowski P., Forrester J.V. CD59 and CD48 expressed by rat retinal pigment epithelial cells are major ligands for CD2-mediated alternative pathway of T cell activation. J. Immunol. 156:1996;3696
24. Mayer L., Shlien R. Evidence for function of Ia molecules on gut epithelial cells in man. J. Exp. Med. 166:1987;1471
25. Moigneon P.H., Chang B.P., Wallner C., Stebbins A.Z., Reinherz E.L. CD2-mediated adhesion facilitates T lymphocyte antigen recognition function. Nature (Lond.). 339:1989;312
26. Mojcik C.F., Shevach E. Adhesion molecules: a rheumatologic perspective. Arthritis Rheum. 6:1997;991
27. Nickoloff B.J., Turka L.A. Immunological functions of non-professional antigen-presenting cells: new insight from studies of T-cell interactions with keratinocytes. Immunol. Today. 15:1994;464
28. Omari K.I., Dorovini-Zis K. Expression and function of lymphocyte function associated antigen-3 (LFA-3) at the blood-brain barrier. Cell. Mol. Biol. 45:1999;25
29. Przepiorka D., Phillips G.L., Ratanatharathorn V., Michele C.F., Sehn L.H., Antin J.H., Lebherz D., Awwad M., Hope J., McClain J.B. A phase II study of BTI-322, a monoclonal anti-CD2 antibody, for treatment of steroid-resistant acute graft-versus-host disease. Blood. 92:1998;4066
30. Qin L.H., Chavin K.D., Lin J.X., Yagita H., Bromberg J.S. Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival. J. Exp. Med. 179:1994;341
31. 2+ in lymphocytes. J. Cell. Biol. 95:1982;189
32. Robb R.J., Munck A., Smith K.A. T cell growth factor receptors. Quantitation, specificity, and biological relevance. J. Exp. Med. 154:1981;1455
33. Savag C.O., Brooks C.J., Harcourt G.C., Picard J.K., King W., Sansom D.M., Willcox N. Human vascular endothelial cells process and present autoantigen to human T cell lines. Int. Immunol. 7:1995;471
34. Sido B., Otto G., Zimmermann R., Müller P., Meuer S., Dengler T.J. Prolonged allograft survival by the inhibition of costimulatory CD2 signals but not by modulation CD48 (CD2 ligand) in the rat. Transplant. Int. 9:1996;S323
35. Sido B., Otto G., Zimmermann R., Müller P., Meuer S., Dengler T.J. Modulation of the CD2 receptor and not disruption of the CD2/CD48 interaction is the principal action of CD2-mediated immunosuppression in the rat. Cell. Immunol. 182:1997;57
36. Singer K.H., Le P.T., Denning S.M., Whichard L.P., Haynes B.F. The role of adhesion molecules in epithelial-T-cell interactions in thymus and skin. J. Invest. Dermatol. 94:1990;85S
37. Sultan P., Schechner J.S., McNiff J.M., Hochman P.S., Hughes C.C.W., Lorber M.I., Askenase P.W., Pober J.S. Blockade of CD2-LFA-3 interactions protects human skin allografts in immunodeficient mouse/human chimeras. Nat. Biotechnol. 15:1997;759
38. Wesphal J.R., Willems H.W., Tax W.J., Koene R.A., Ruiteer D.J., de Waal R.M. The proliferative response of human T cells to allogeneic IFN-gamma-treated endothelial cells is mediated via both CD2/LFA-3 and LFA-1/ICAM-1 and -2 adhesion pathways. Transplant. Immunol. 1:1993;183
39. William C.H., Steven J.B., Barbara E.B. Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58. J. Immunol. 150:1993;2607
40. Wiskocil R., Weiss A., Imboden J., Kamin-Lewis R., Stobo J. Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes. J. Immunol. 134:1984;1599
41. Yusuf-Makagiansar, H., Makagiansar, I.T., Siahaan T.J., 2001. Inhibition of the adherence of T-lymphocytes to epithelial cells by a cyclic peptide derived from inserted domain of lymphocyte function-associated antigen-1. Inflammation 25, 203-214.