Theophylline impairs memory/learning in developing mice

Brain and Development

Volumn 26, Issue 7, 2004, Pages 448-452

  Hirose, Mieko ^a   Yokoyama, Hiroyuki ^a   Iinuma, Kazuie ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Elevated plus maze test; Learning; Locomotor activity; Memory; Theophylline

Indexed keywords

THEOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; LATENT PERIOD; LEARNING DISORDER; LOCOMOTION; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NONHUMAN;

AGE FACTORS; ANIMALS; ASTHMA; BRAIN; BRONCHODILATOR AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERKINESIS; LEARNING DISORDERS; MALE; MAZE LEARNING; MEMORY; MEMORY DISORDERS; MICE; MOTOR ACTIVITY; REACTION TIME; THEOPHYLLINE;

EID: 4444293335     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.braindev.2003.12.008     Document Type: Article

References (27)

1. Gaudreault P., Guay J. Theophylline poisoning. Pharmacological considerations and clinical management. Med Toxicol. 1:1986;169-191
2. Vaucher Y., Lightner E.S., Welson P.D. Theophylline poisoning. J Pediatr. 90:1977;827-830
3. Baker M.D. Theophylline toxicity in children. J Pediatr. 109:1986;538-542
4. Wasser W.G., Bonheim H.E., Richardson B.K. Theophylline madness. Ann Intern Med. 95:1981;191
5. Schraa J.C., Dirks J.F. The influence of corticosteroids and theophylline on cerebral function. A review. Chest. 82:1982;181-185
6. Auritt W.A., MeGeady S.J., Mansmann H.C. Jr. The relationship of cerebrospinal fluid and plasma theophylline concentrations in children and adolescents taking theophylline. J Allergy Clin Immunol. 75:1985;731-735
7. Furukawa C.T., DuHamel T.R., Weimer L., Shapiro G.G., Pierson W.E., Bierman C.W. Cognitive and behavioral findings in children taking theophylline. J Allergy Clin Immunol. 81:1988;83-88
8. Furukawa C.T., Shapiro G.G., Bierman C.W., Kraemer M.J., Ward D.J., Pierson W.E. A double-blind study comparing the effectiveness of cromolyn sodium and sustained-release theophylline in childhood asthma. Pediatrics. 74:1984;453-459
9. McLoughlin J., Nall M., Isaacs B., Petrosko J., Karibo J., Lindsey B. The relationship of allergies and allergy treatment to school performance and student behavior. Ann Allergy. 51:1983;506-510
10. Rachelefsky G.S., Wo J., Adelson J., Mickey M.R., Spector S.L., Katz R.M., et al. Bahavior abnormalities and poor school performance due to oral theophylline use. Pediatrics. 78:1986;1133-1138
11. Springer C., Goldenberg B., Ben Dov I., Godfrey S. Clinical, physiologic, and psychologic comparison of treatment by cromolyn theophylline in childhood asthma. J Allergy Clin Immunol. 76:1985;64-69
12. Izquierdo J.A. Effect of caffeine on the memory of the mouse. Psychopharmacology (Berlin). 61:1979;29-30
13. Izquierdo J.A. Effect of caffeine, aminophylline and pentoxifylline on memory processes in mice. Acta Physiol Lat Am. 31:1981;207-209
14. Itoh J., Nabeshima T., Kameyama T. Utility of an elevated plus-maze for the evaluation of memory in mice: effects of nootropics, scopolamine and electroconvulsive shock. Psychopharmacology (Berlin). 101:1990;27-33
15. Miyazaki S., Imaizumi M., Onodera K. Ameliorating effects of histidine on scopolamine-induced learning deficits using an elevated plus-maze test in mice. Life Sci. 56:1995;1563-1570
16. Miyazaki S., Imaizumi M., Machida H. The effects of anxiolytics and anxiogneics on evaluation of learning and memory in an elevated plus-maze test in mice. Methods Find Exp Clin Pharmacol. 17:1995;121-127
17. Yokoyama H., Onedera K., Yagi T., Iinuma K. Therapeutic doses of theophylline exert proconvulsant effects in developing mice. Brain Dev. 19:1997;403-407
18. Ramzan I.M., Levy G. Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats. J Pharmacol Exp Ther. 236:1986;708-713
19. Schlieper A., Alcock D., Beaudry P., Feldman W., Leiking L. Effects of therapeutic plasma concentrations of theophylline on behavior, cognitive processing, and affect in children with asthma. J Pediatr. 118:1991;449-455
20. Rappaport L., Coffman H., Guare R., Fenton T., DeGraw C., Twarog F. Effects of theophylline on behavior and learning in children with asthma. Am J Dis Child. 143:1989;368-372
21. Ohno M., Watanabe S. Working memory failure by stimulation of hippocampal adenosine Al Receptors in rats. NeuroReport. 7:1996;3013-3016
22. Asztalos Z., Lossos M., Friedrich P. On the pharmacological phenocopying of memory mutations in Drosophila: alkylxanthines accelerate memory decay. Behav Genet. 21:1991;495-511
23. Zarrindast M.R. Effects of high doses of theophylline on memory acquisition. Psychopharmacology (Berlin). 122:1995;307-311
24. McDonald J.W., Johnston M.V., Young A.B. Differnetial ontogenic development of three receptors comprising the NMDA receptor/channel complex in the rat hippocampus. Exp Neurol. 110:1990;237-247
25. Insel T.R., Miller L.P., Gelhard R.E. The ontogeny of excitatory amino acid receptors in rat forebrain - I. N-methyl-D-aspartate and quisqualate receptors. Neuroscience. 35:1990;31-43
26. Holmes G.L., Thompson J.L. Effects of kainic acid on seizure susceptibility in the developing brain. Brain Res. 467:1988;51-59
27. Velisek L., Veliskova J., Ptachewich Y., Ortiz J., Shinnar S., Moshe S.L. Age-dependent effects of gamma-aminobutyric acid agents on flurothyl seizures. Epilepsia. 36:1995;636-643