The effects of ochratoxin A on lipid peroxidation and antioxidant enzymes: A protective role of melatonin

Cell Biology and Toxicology

Volumn 20, Issue 4, 2004, Pages 213-219

  Soyoz M ^a   Ozcelik N ^a   Kilinc I ^a   Altuntas I ^a  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

antioxidant; enzyme; liver; melatonin; ochratoxin A

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; MELATONIN; OCHRATOXIN; SUPEROXIDE DISMUTASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; INTOXICATION; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; CARCINOGENS; CATALASE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; LIVER; MALE; MELATONIN; OCHRATOXINS; PROTECTIVE AGENTS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ANIMALIA; FELIS CATUS;

EID: 4444288552     PISSN: 07422091     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:CBTO.0000038459.98032.34     Document Type: Article

References (29)

1. Atroshi F, Rizzo A, Sankari S, Biese I, Westermarck T, Veijalainen P. Liver enzyme activities of rats exposed to ochratoxin A and T-2 toxin with antioxidant. Bull Environ Contam Toxicol. 2000;64:586-92.
2. Aydin G, Özçelik N, Çiçek E, Soyöz M. Histopathologic changes in liver and renal tissues induced by ochratoxin A and melatonin in rats. Hum Exp Toxicol. 2003;22:383-91.
3. Baudrimont I, Berbeder A-M, Charbi A. Effect of superoxide dismutase and catalase on the nephrotoxicity induced by subchronical administration of ochratoxin A in rats. Toxicology. 1994;89:101-11.
4. Bendele AM, Carlton WW, Krogh P, Lillehoj EB. Ochratoxin A carcinogenesis in the (C57BL/6J x C3H) F1 mouse. J Natl Cancer Inst. 1985;75:733-42.
5. Benesic A, Mildenberger S, Gekle M. Nephritogenic ochratoxin A interferes with hormonal signalling in immortalized human kidney epithelial cells. Eur J Physiol. 2000;439:278-87.
6. Boorman GA. NTP technical report on the toxicology and carcinogenic studies of ochratoxin A in F344/n rats (gavage studies). NIH Publication. 1989:89-2813.
7. Cheesman KH, Slater TF. An introduction to free radical biochemistry. Br Med Bull. 1993;49:481-93.
8. Creppy EE, Baudrimont I, Betbeder A-M. Prevention of nephrotoxicity of ochratoxin A, a food contaminant. Toxicol Lett. 1995;82/83:869-77.
9. Draper HH, Hadley M. Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol. 1990;186: 421-31.
10. Gautier J-C, Holzhaeuser D, Markovic J, Gremaud E, Schilter B, Turesky J. Oxidative damage and stress response from ochratoxin A exposure in rats. Free Radic Biol Med. 2001; 30:1089-98.
11. Gekle M, Silbernagl S. Renal toxicodynamics of ochratoxin A: a pathophysiological approach. Kidney Blood Pressure Res. 1996;19:225-35.
12. Hong JT, Lee MK, Park KS, et al. Inhibitory effect of peroxisome proliferator-activated receptor gamma agonist on ochratoxin A-induced cytotoxicity and activation of transcription factors in cultured rat embryonic midbrain cells. J Toxicol Environ Health A. 2002;65:407-18.
13. IARC. Evaluation of carcinogen risks to humans. Some naturally occurring substances; foods, items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monogr Eval Carcinog Risks Hum. 1993;56:489-521.
14. Luck H. Catalase. In: Bergmeyer H.-U., editor. Methods of enzymatic analysis. New York: Academic Press; 1963:885-8.
15. Meki MA, Hussein AA. Melatonin reduces oxidative stress induced by ochratoxin A in rat liver and kidney. Comp Biochem Physiol Part C. 2001;130:305-13.
16. Ohta Y. Kongo M, Sasaki E, Nishida K, Ishiguro I. Therapeutic effect of melatonin on carbon tetrachloride-induced acute liver injury in rats. J Pineal Res. 2000;28:119-26.
17. Omar RF, Rahimtula AD, Bartsch H. Role of cytochrome P450 in ochratoxin A stimulated lipid peroxidation. J Biochem Toxicol. 1991;6:203-9.
18. Özçelik N, Soyöz M, Kilinç İ. The effects of ochratoxin A on oxidative damage in rat kidney: protective role of melatonin. J Appl Toxicol. 2004;24:211-15.
19. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967;70:158-69.
20. Petzinger E, Ziegler K. Ochratoxin A from a toxicological perspective. J Vet Pharmacol Therap. 2000;23:91-8.
21. Pieri C, Marra M, Moroni F, Decchioni R, Marcheselli F. Melatonin: a peroxyl radical scavenger more potent than vitamin E. Life Sci. 1994;55:271-6.
22. Rahimtula AD, Bereziat JC, Bussacchini-Griot V, Bartsch H. Lipid peroxidation as a possible cause of ochratoxin A toxicity. Biochem Pharmacol. 1988;37:4469-77.
23. Reiter RJ, Tang L, Garcia JJ, Munoz-Hoyos A. Pharmacological actions of melatonin in oxygen radical pathophysiology. Life Sci. 1997;60:2255-71.
24. Reiter RJ, Tan D, Osuna C, Gitto E. Actions of melatonin in the reduction of oxidative stress. J Biomed Sci. 2000;7:444-58.
25. Sauvant C, Silbernagl S, Gekle M. Exposure to ochratoxin A impairs organic anion transport in proximal-tubule-derived opossum kidney cells. J Pharmacol Exp Ther. 1998;287:13-20.
26. Subramanian S, Kanthasamy A, Balasubramanian N, Sekar N, Govindasamy S. Ochratoxin A toxicity on carbohydrate metabolism in rats. Bull Environ Contam Toxicol. 1989;43: 180-4.
27. Van Ginkel G, Sevanian A. Lipid peroxidation-induced membrane structural alterations. Methods Enzymol. 1994;233: 273-88.
28. Wolden-Hanson T, Mitton DR, McCants RL, et al. Daily melatonin administration to middle-aged male rats supresses body weight, intraabdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology. 2000;141:487-97.
29. Woolliams JA, Wiener G, Anderson PH, McMurray CH. Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood in various breed crosses of sheep. Res Vet Sci. 1983;34:253-6.