Optimizing target selection and development strategy in cancer treatment: The next wave

Current Medicinal Chemistry - Anti-Cancer Agents

Volumn 4, Issue 5, 2004, Pages 445-447

  Sausville, Edward A ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE; BIOLOGICAL MARKER; BORTEZOMIB; CD20 ANTIGEN; CETUXIMAB; CYTOTOXIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR ANTAGONIST; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GEFITINIB; IMATINIB; RITUXIMAB; TRASTUZUMAB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

APOPTOSIS; CANCER; CANCER CHEMOTHERAPY; CANCER RESEARCH; CARCINOGENESIS; CELL PROLIFERATION; CLINICAL TRIAL; DISEASE MODEL; DRUG METABOLISM; DRUG RESEARCH; DRUG RESPONSE; DRUG SENSITIVITY; DRUG TARGETING; DRUG UPTAKE; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC PROCEDURES; HOST RESISTANCE; HUMAN; MICROENVIRONMENT; MOLECULAR BIOLOGY; ONTOGENY; PATHOPHYSIOLOGY; PATIENT SELECTION; PROCESS OPTIMIZATION; PROTEIN EXPRESSION; REVIEW; STROMA CELL; TREATMENT OUTCOME; TREATMENT PLANNING; TUMOR DIFFERENTIATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIVISION; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; NEOPLASMS;

EID: 4444286882     PISSN: 15680118     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568011043352876     Document Type: Review

References (7)

1. Hainsworth, J.D. Semin. Oncol., 2002, 29(1 Suppl 2), 25.
2. Paez, J.G.; Janne, P.A.; Lee, J.C.; Tracy, S.; Greulich, H.; Gabriel, S.; Herman, P.; Kaye, F.J.; Lindeman, N.; Boggon, T.J.; Naoki, K.; Sasaki, H., Fujii, Y.; Eck, M.J.; Sellers, W.R., Johnson, B.E., Meyerson, M. Science, 2004, Apr. 29 Epub ahead of print..
3. Lynch, T.J.; Bell, D.W.; Sordella, R.; Gurubhagavatula, S.; Okimoto, R.A; Brannigan, B.W.; Harris, P.L.; Haserlat, S.M.; Supko, J.G.; Haluska, F.G.; Louis, D.N.; Christiani, D.C.; Settleman, J.; Haber, D.A. N. Engl. J. Med., 2004, 350, 2129.
4. Debiec-Rychter, M.; Dumez, H.; Judson, I.; Wasag, B.; Verweij, J., Brown, M.; Dimitrijevic, S.; Sciot, R.; Stul, M.; Vranck, H.; Scurr, M.; Hagemeijer, A.; van Glabbeke, M.; van Oosterom, A.T.; EORTC Soft Tissue and Bone Sarcoma Group. Eur. J. Cancer., 2004, 40, 689.
5. Morgan, B.; Thomas, A.L.; Drevs, J.; Hennig, J.; Buchert, M.; Jivan, A.; Horsfie, M.A.; Mross, K.; Ball, H.A.; Lee, L.; Mietlowski, W.; Fuxuis, S.; Unger, C.; O'Byrne, K.; Henry, A.; Cherryman, G.R.; Laurent, D.; Dugan, M.; Marme, D.; Steward, W.P. J. Clin. Oncol., 2003, 21, 3897.
6. Seeburg, P.H.; Colby, W.W.; Capon, D.H.; Goeddel, D.V.; Levinson, A.D. Nature, 1984, 312, 71.
7. Damaraju V.L.; Damaraju, S.; Young, J.D.; Baldwin, S.A.; Mackey, J.; Sawyer, M.B.; Cass, C.E. Oncogene, 2003, 22, 7524.