Vasorelaxation by amentoflavone isolated from Selaginella tamariscina

Planta Medica

Volumn 70, Issue 8, 2004, Pages 718-722

  Dae, Gill Kang ^a   Ming, Hao Yin ^a   Oh, Hyuncheol ^b   Dae, Ho Lee ^c   Ho, Sub Lee ^a  

^a Wonkwang University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^c Jeju National University Hospital   (South Korea)

Author keywords

Amentoflavone; cGMP; Nitric oxide; Selaginella tamariscina; Vasorelaxation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; AMENTOFLAVONE; ATROPINE; BIFLAVONOID; CALCIUM CHANNEL; CYCLIC GMP; GLIBENCLAMIDE; INDOMETACIN; METHYLENE BLUE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; PLANT EXTRACT; POTASSIUM CHANNEL; PROPRANOLOL; SELAGINELLA TAMARISCINA EXTRACT; TETRYLAMMONIUM; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL TISSUE; AORTA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM; MALE; MEDICINAL PLANT; NONHUMAN; PURIFICATION; RAT; SELAGINELLA TAMARISCINA; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; AORTA; BIFLAVONOIDS; ENDOTHELIUM, VASCULAR; MALE; METHYLENE BLUE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; OXADIAZOLES; PHENYLEPHRINE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SELAGINELLACEAE;

ANIMALIA; SELAGINELLA; SELAGINELLA TAMARISCINA;

EID: 4444276820     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-827201     Document Type: Article

References (22)

1. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288: 373-6
2. Jaffe EA. Physiologic functions of normal endothelial cells. Ann N Y Acad Sci 1985; 454: 279-91
3. Beny JL, Brunet PC. Neither nitric oxide nor nitroglycerin accounts for all the characteristics of endothelially mediated vasodilatation of pig coronary arteries. Blood Vessels. 1988; 25: 308-11
4. Palmer RM, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333: 664-6
5. Hirano S, Agata N, Hara Y, Iguchi H, Shirai M, Tone H, Urakawa N. Pirarubicin-induced endothelium-dependent relaxation in rat isolated aorta. J Pharm Pharmacol 1991; 43: 848-54
6. Gray DW, Marshall I. Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide. Br J Pharmacol 1992; 107: 691-6
7. Sato K, Ozaki H, Karaki H. Changes in cytosolic calcium level in vascular smooth muscle strip measured simultaneously with contraction using fluorescent calcium indicator fura 2. J Pharmacol Exp Ther 1988; 246: 294-300
8. Lee HS, Oh WK, Kim BY, Ahn SC, Kang DO, Shin DI, Kim J, Mheen TI, Ahn JS. Inhibition of phospholipase C gamma 1 activity by amentoflavone isolated fromSelaginella tamariscina. Planta Medica 1996; 62: 293-6
9. Lin YM, Chen FC, Lee KH. Hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids. Planta Medica 1989; 55: 166-8
10. Lobstein-Guth A, Briancon-Scheid F, Victoire C, Haag-Berrurier M, Anton R. Isolation of amentoflavone from Ginkgo biloba. Planta Medica 1988; 54: 555-6
11. Mora A, Paya M, Rios JL, Alcaraz MJ. Structure-activity relationships of polymethoxyflavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation. Biochem Pharmacol 1990; 40: 793-7
12. Lin YM, Anderson H, Flavin MT, Pai YH, Mata-Greenwood E, Pengsuparp T, Pezzuto JM, Schinazi RF, Hughes SH, Chen FC. In vitro anti-HIV activity of biflavonoids isolated from Rhus succedanea and Garcinia multiflora. J Nat Prod 1997; 60: 884-8
13. 2+ releaser in skeletal muscle sarcoplasmic reticulum. Eur J Pharmacol 1999; 372: 97-102
14. Butterweck V, Nahrstedt A, Evans J, Hufeisen S, Rauser L, Savage J, Popadak B, Ernsberger P, Roth BL. In vitro receptor screening of pure constituents of St. John's wort reveals novel interactions with a number of GPCRs. Psychopharmacology 2002; 162: 193-202
15. Chakravarthy BK, Rao YV, Gambhir SS, Gode KD. Isolation of amentoflavone from Selaginella rupestris and its pharmacological activity on central nervous system, smooth muscles and isolated frog heart preparations. Planta Medica 1981; 43: 64-70
16. Kim SZ, Kim SH, Park JK, Koh GY, Cho KW. Presence and biological activity of C-type natriuretic peptide-dependent guanylate cyclase-coupled receptor in the penile corpus cavernosum. J Urol 1998; 159: 1741-6
17. Murad F. Cyclic guanosine monophosphate as a mediator of vasodilation. J Clin Invest 1986; 78: 1-5
18. Gordon JL, Martin W. Stimulation of endothelial prostacyclin production plays no role in endothelium-dependent relaxation of the pig aorta. Br J Pharmacol 1983; 80: 179-86
19. Satake N, Kiyoto S, Shibata S, Gandhi V, Jones DJ, Morikawa M. Possible mechanisms of inhibition with atropine against noradrenaline-induced contraction in the rabbit aorta. Br J Pharmacol 1992; 107: 553-8
20. Loeb AL, Izzo NJ Jr, Johnson RM, Garrison JC, Peach MJ. Endothelium-derived relaxing factor release associated with increased endothelial cell inositol trisphosphate and intracellular calcium. Am J Cardiol 1988; 62: 36G-40G
21. + channels in arterial smooth muscle. Science 1989; 245: 177-80
22. Mehrke G, Daut J. The electrical response of cultured guinea-pig coronary endothelial cells to endothelium-dependent vasodilators. J Physiol 1990; 430: 251-72