Influence of inorganic mobile phase additives on the retention, efficiency and peak symmetry of protonated basic compounds in reversed-phase liquid chromatography

Journal of Chromatography A

Volumn 1049, Issue 1-2, 2004, Pages 63-73

  Pan, Li ^a   Lobrutto, Rosario ^a,c   Kazakevich, Yuri V ^b,c   Thompson, Richard ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b SETON HALL UNIVERSITY   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Basic analytes; Chaotropicity; Efficiency; Hexafluorophosphate; Loading capacity; Peak symmetry; Perchlorate

Indexed keywords

COUNTERANIONS; PROTONATION;

ADDITIVES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHENOLS; SODIUM COMPOUNDS; SOLVENT EXTRACTION;

AROMATIC HYDROCARBONS;

AGENTS ACTING ON THE EYE; ANION; BENZYL DERIVATIVE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BROMINE; CHLORINE; DRUG ADDITIVE; FLUORINE; HYDROGEN; INORGANIC ACID; OXYGEN; PHENOL; POTASSIUM; SODIUM; TOLUENE;

ARTICLE; CHEMICAL BOND; CONCENTRATION (PARAMETERS); FLUID RETENTION; MATHEMATICAL COMPUTING; PRIORITY JOURNAL; PROTON TRANSPORT; REVERSED PHASE LIQUID CHROMATOGRAPHY; SOLVATION; STRUCTURE ANALYSIS;

ALGORITHMS; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; INDICATORS AND REAGENTS; INORGANIC CHEMICALS; LABETALOL; OPHTHALMIC SOLUTIONS; SULFONAMIDES; THIOPHENES;

EID: 4444276284     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.07.019     Document Type: Article

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