Regioselective functionalization of guanine: Simple and practical synthesis of 7- and 9-alkylated guanines starting from guanosine

Synthesis

Volumn , Issue 12, 2004, Pages 2026-2034

  Kalayanov, Genadiy ^a,b   Jakša, Suzana ^a   Scarcia, Tommaso ^c   Kobe, Jože ^a  

^a NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^b MEDIVIR AB   (Sweden)

^c UNIVERSITY OF BARI   (Italy)

Author keywords

Alkylations; Benzylation; Hydrogenations; N2 acetyl 7 and 9 benzylguanine; Regioselectivity

Indexed keywords

GUANINE; REGIOSELECTIVE FUNCTIONALIZATION;

ALKYLATION; DRUG PRODUCTS; HYDROGENATION; ISOMERS; SULFONATION;

NITROGEN COMPOUNDS;

1 METHYL 2 PYRROLIDINONE; 2 AMINOPURINE; ALKYLATING AGENT; GUANINE DERIVATIVE; GUANOSINE; INORGANIC SALT; PRODRUG; SULFONIC ACID DERIVATIVE;

ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; DEOXYGENATION; HYDROGENATION; ISOMER; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

EID: 4444273429     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-829174     Document Type: Article

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