Quantitative determination of the antitumor alkyl ether phospholipid edelfosine by reversed-phase liquid chromatography-electrospray mass spectrometry: Application to cell uptake studies and characterization of drug delivery systems

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 810, Issue 1, 2004, Pages 85-92

  Blanco Príeto, María J ^a   Campanero, Miguel A ^b   Mollinedo, Faustino ^c  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY CLINIC OF NAVARRA   (Spain)

^c CSIC   (Spain)

Author keywords

Antitumoral agents; Drug delivery systems; Edelfosine

Indexed keywords

CELL LYSIS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY (ESI-MS); MEAN EXTRACTION RECOVERY; POLYMER PRECIPITATION;

ASSAYS; AUTOMATION; CELLS; CONTROLLED DRUG DELIVERY; ERROR ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONIZATION; MASS SPECTROMETRY; POLYMERIC MEMBRANES; PRECIPITATION (CHEMICAL);

ETHERS;

ALKYLLYSOPHOSPHOLIPID; ANTINEOPLASTIC AGENT; EDELFOSINE;

ACCURACY; ANALYTIC METHOD; ANALYTICAL ERROR; ARTICLE; AUTOMATION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG SCREENING; DRUG UPTAKE; ELECTROSPRAY MASS SPECTROMETRY; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH THROUGHPUT SCREENING; ION MONITORING; LINEAR SYSTEM; MASS SPECTROMETRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; REPRODUCIBILITY; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE;

ANTINEOPLASTIC AGENTS; CALIBRATION; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DELIVERY SYSTEMS; HL-60 CELLS; HUMANS; INDICATORS AND REAGENTS; PHOSPHOLIPID ETHERS; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 4444253424     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.07.013     Document Type: Article

References (21)

1. P.G. Munder, and O. Westphal Chem. Immunol. 49 1990 206
2. H. Brachwitz, and C. Vollgraf Pharmacol. Ther. 66 1995 39
3. W.J. Houlihan, M. Lohmeyer, P. Workman, and S.H. Cheon Med. Res. Rev. 15 1995 157
4. C. Gajate, and F. Mollinedo Curr. Drug Metab. 3 2002 491
5. F. Mollinedo, J.L. Fernandez-Luna, and C. Gajate Cancer Res. 57 1997 1320
6. R. Andreesen, J. Osterholz, G.A. Luckenbach, U. Costabel, A. Schulz, and V. Speth J. Natl. Cancer Inst. 72 1984 53
7. F. Mollinedo, R. Martinez-Dalmau, and M. Modolell Biochem. Biophys. Res. Commun. 192 1993 603
8. L. Diomede, F. Colotta, B. Piovani, F. Re, E.J. Modest, and M. Salmona Int. J. Cancer 53 1993 124
9. L. Diomede, B. Piovani, F. Re, P. Principe, F. Colotta, E.J. Modest, and M. Salmona Int. J. Cancer 57 1994 645
10. C. Gajate, R.I. Fonteriz, C. Cabaner, G. Alvarez-Noves, Y. Alvarez-Rodriguez, M. Modolell, and F. Mollinedo Int. J. Cancer 85 2000 674
11. C. Gajate, and F. Mollinedo Blood 98 2001 3860
12. W.R. Vogler, and W.E. Berdel J. Hematother. 2 1993 93
13. M.P. Königsmann, M. Notter, C.A. Papadimitrou, D. Oberberg, B. Reufi, and C. Mücke Bone Marrow Transpl. 18 1996 549
14. K. Lawrence, W. Fung, and M. Saltzman Adv. Drug Del. Rev. 26 1997 209
15. I. Ahmad, J.J. Filep, J.C. Franklin, A.S. Janoff, G.R. Masters, and J. Pattassery Cancer Res. 57 1997 1915
16. M.J. Blanco-Príeto, E. Fattal, A. Gulik, J.C. Delieu, B.P. Roques, and P. Couvreur J. Contr. Rel. 43 1997 81
17. M.J. Blanco-Príeto, K. Besseghir, O. Zerbe, D. Andris, P. Orsolini, F. Heimgartner, H.P. MerklE, and B. Gander J. Contr. Rel. 67 2000 19
18. J. Coene, M.E. Ramos, E. Van den Eeckhout, P. Sandra, and W. Van den Bossche Chromatographia 30 1990 414
19. J. Coene, M. Ghis, E. Van den Eeckhout, W. Van den Bossche, and P. Sandra J. Chromatogr. 553 1991 285
20. J. Coene, E. Van den Eeckhout, P. Herdewijn, and P. Sandra J. Chromatogr. 612 1993 21
21. W.F. Steelant, E.A. Bruyneel, M.M. Mareel, and E. Van den Eeckhout Anal. Biochem. 227 1995 246