Treatment intensity significantly influencing fibrosis in bone marrow independently of the cytogenetic response: Meta-analysis of the long-term results from two prospective controlled trials on chronic myeloid leukemia

Leukemia

Volumn 18, Issue 9, 2004, Pages 1460-1467

  Buesche, Guntram ^a   Freund, M ^b   Hehlmann, R ^c   Georgii, A ^a   Ganser, A ^a   Hecker, H ^a   Heimpel, H ^d   Fonatsch, C ^e   Heinze, B ^f   Pfirrmann, M ^g   Holgado, S ^a,i   Schmeil, A ^a   Tobler, A ^h   Hasford, J ^g   Buhr, T ^a   Kreipe, H H ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY HOSPITAL ULM   (Germany)

^e MEDICAL UNIVERSITY OF VIENNA   (Austria)

^f UNIVERSITY OF ULM   (Germany)

^g UNIVERSITY OF MUNICH   (Germany)

^h UNIVERSITY OF BERN   (Switzerland)

ⁱ Laboratorio de Patologia   (Argentina)

Author keywords

Bone marrow biopsies; Chronic myeloid leukemia; Cytosine arabinoside; Interferon ; Myelofibrosis

Indexed keywords

ALPHA INTERFERON; BUSULFAN; CYTARABINE; ANTINEOPLASTIC AGENT;

ADULT; ARTICLE; BONE MARROW BIOPSY; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOGENETICS; DISEASE COURSE; DOSE RESPONSE; DRUG EFFICACY; DRUG MEGADOSE; DRUG SURVEILLANCE PROGRAM; FEMALE; HUMAN; LOW DRUG DOSE; MALE; META ANALYSIS; MORTALITY; MYELOFIBROSIS; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RISK ASSESSMENT; TREATMENT FAILURE; BIOPSY; BONE MARROW; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; DRUG RESISTANCE; MIDDLE AGED; MYELOID LEUKEMIA; PATHOLOGY; RISK FACTOR; SURVIVAL RATE;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BIOPSY; BONE MARROW; CHROMOSOME ABERRATIONS; CONTROLLED CLINICAL TRIALS; CYTARABINE; CYTOGENETIC ANALYSIS; DISEASE PROGRESSION; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; INTERFERON-ALPHA; LEUKEMIA, MYELOID, CHRONIC; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; MIDDLE AGED; MYELOFIBROSIS; PROSPECTIVE STUDIES; RISK FACTORS; SURVIVAL RATE;

EID: 4444245828     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403451     Document Type: Article

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