Characterization of heme uptake cluster genes in the fish pathogen Vibrio anguillarum

Journal of Bacteriology

Volumn 186, Issue 18, 2004, Pages 6159-6167

  Mouriño, Susana ^a   Osorio, Carlos R ^a   Lemos, Manuel L ^a  

^a Santiago de Compostela Spain   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; CARRIER PROTEIN; EXBB PROTEIN; HEME; HEME RECEPTOR; HEMIN; HEMOGLOBIN; IRON; MEMBRANE RECEPTOR; PERIPLASMIC BINDING PROTEIN; PERMEASE; PORPHYRIN; PROTEIN EXBD; PROTEIN HUVA; PROTEIN HUVB; PROTEIN HUVX; PROTEIN HUVZ; PROTEIN TONB; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL METABOLISM; BACTERIAL STRAIN; BACTERIUM MUTANT; CHROMOSOME DELETION; CONTROLLED STUDY; COSMID; FISH DISEASE; GENE CLUSTER; GENETIC COMPLEMENTATION; HUVA GENE; HUVB GENE; HUVBCD GENE; HUVC GENE; HUVD GENE; HUVX GENE; HUVZ GENE; LISTONELLA ANGUILLARUM; NONHUMAN; PLASMID; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TONB EXBBD GENE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BIOLOGICAL TRANSPORT, ACTIVE; CLONING, MOLECULAR; DNA, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; GENE ORDER; GENES, BACTERIAL; HEME; HEMIN; HEMOGLOBINS; IRON; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PERIPLASMIC BINDING PROTEINS; PORPHYRINS; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SYNTENY; VIBRIO;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; LISTONELLA ANGUILLARUM; NEGIBACTERIA; VIBRIO;

EID: 4444243381     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.186.18.6159-6167.2004     Document Type: Article

References (44)

1. Chen, C.-Y., K.-M. Wu, Y.-C. Chang, C.-H. Chang, H.-C. Tsai, T.-L. Liao, Y.-M. Liu, H.-J. Chen, A. B.-T. Shen, J.-C. Li, T.-L. Su, C.-P. Shao, C.-T. Lee, L.-I. Hor, and S.-F. Tsai. 2003. Comparative genome analysis of Vibrio vulnificus, a marine pathogen. Genome Res. 13:2577-2587.
2. Conchas, R. F., M. L. Lemos, J. L. Barja, and A. E. Toranzo. 1991. Distribution of plasmid- and chromosome-mediated iron uptake systems in Vibrio anguillarum strains of different origins. Appl. Environ. Microbiol. 57:2956-2962.
3. Correa, N., C. M. Lauriano, R. McGee, and K. E. Klose. 2000. Phosphorylation of the flagellar regulatory protein FlrC is necessary for Vibrio cholerae motility and enhanced colonization. Mol. Microbiol. 35:743-755.
4. Crosa, J. H. 1989. Genetics and molecular biology of siderophore-mediated iron transport in bacteria. Microbiol. Rev. 53:517-530.
5. Ditta, G., S. Stanfield, D. Corbim, and D. R. Helinski. 1980. Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti. Proc. Natl. Acad. Sci. USA 77:7347-7351.
6. Eberspächer, B., and V. Braun. 1980. The involvement of cytochromes in the uptake of ferrichrome by Escherichia coli K-12. FEMS Microbiol. Lett. 7:61-64.
7. Genco, C. A., and D. W. Dixon. 2001. Emerging strategies in microbial haem capture. Mol. Microbiol. 39:1-11.
8. Goldberg, J. B., and D. E. Ohman. 1984. Cloning and expression in Pseudomonas aeruginosa of a gene involved in the production of alginate. J. Bacteriol. 158:1115-1121.
9. Gualerzi, C. O., and C. L. Pon. 1990. Initiation of mRNA translation in prokaryotes. Biochemistry 29:5881-5889.
10. Haddock, B. A., and H. U. Schairer. 1973. Electron-transport chains of Escherichia coli. Reconstitution of respiration in a 5-aminolevulinic acid-requiring mutant. Eur. J. Biochem. 35:34-45.
11. Hall, T. A. 1999. BioEdit: a user-friendly biological sequence alignment editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp. Ser. 41:95-98.
12. Heidelberg, J. F., J. A. Eisen, W. C. Nelson, R. A. Clayton, M. L. Gwinn, R. J. Dodson, D. H. Haft, E. K. Hickey, J. D. Peterson, L. Umayam, S. R. Gill, K. E. Nelson, T. D. Read, H. Tettelin, D. Richardson, M. D. Ermolaeva, J. Vamathevan, S. Bass, H. Qin, I. Dragoi, P. Sellers, L. McDonald, T. Utterback, R. D. Fleishmann, W. C. Nierman, O. White, S. L. Salzberg, H. O. Smith, R. R. Colwell, J. J. Mekalanos, J. C. Venter, and C. M. Fraser. 2000. DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae. Nature 406:477-483.
13. Henderson, D. P., and S. M. Payne. 1993. Cloning and characterization of the Vibrio cholerae genes encoding the utilization of iron from haemin and haemoglobin. Mol. Microbiol. 7:461-469
14. Henderson, D. P., E. E. Wyckoff, C. E. Rashidi, and A. L. Oldham. 2001. Characterization of the Plesiomonas shigelloides genes encoding the heme iron utilization system. J. Bacteriol. 183:2715-2723.
15. Knauf, V. C., and E. W. Nester. 1982. Wide host range cloning vectors: a cosmid clone bank of an Agrobacterium Ti plasmid. Plasmid 8:45-54.
16. Köster, W. L., L. A. Actis, L. S. Waldbeser, M. E. Tolmasky, and J. H. Crosa. 1991. Molecular characterization of the iron transport system mediated by the pJM1 plasmid in Vibrio anguillarum 775. J. Biol. Chem. 266:23829-23833.
17. 12. Res. Microbiol. 152:291-301.
18. Lee, B. C. 1995. Quelling the red menace: haem capture by bacteria. Mol. Microbiol. 18:383-390.
19. Lemos, M. L., P. Salinas, A. E. Toranzo, J. L. Barja, and J. H. Crosa. 1988. Chromosome-mediated iron uptake system in pathogenic strains of Vibrio anguillarum. J. Bacteriol. 170:1920-1925.
20. Litwin, C. M., and B. L. Byrne. 1998. Cloning and characterization of an outer membrane protein of Vibrio vulnificus required for heme utilization: regulation of expression and determination of the gene sequence. Infect. Immun. 66:3134-3141.
21. Litwin, C. M., and J. Quackenbush. 2001. Characterization of a Vibrio vulnificus LysR homologue, HupR, which regulates expression of the haem uptake outer membrane protein, HupA. Microb. Pathog. 31:295-307.
22. Makino, K., K. Oshima, K. Kurokawa, K. Yokoyama, T. Uda, K. Tagomori, Y. Iijima, M. Najima, M. Nakano, A. Yamashita, Y. Kubota, S. Kimura, T. Yasunaga, T. Honda, H. Shinagawa, M. Hattori, and T. Iida. 2003. Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism distinct from that of V. cholerae. Lancet 361:743-749.
23. Mazoy, R., and M. L. Lemos. 1991. Iron-binding proteins and heme compounds as iron sources for Vibrio anguillarum. Curr. Microbiol. 23:221-226.
24. Mazoy, R., and M. L. Lemos. 1996. Identification of heme-binding proteins in the cell membranes of Vibrio anguillarum. FEMS Microbiol. Lett. 135:265-270.
25. Mazoy, R., C. R. Osorio, A. E. Toranzo, and M. L. Lemos. 2003. Isolation of mutants of Vibrio anguillarum defective in haeme utilisation and cloning of huvA, a gene coding for an outer membrane protein involved in the use of haeme as iron source. Arch. Microbiol. 179:329-338.
26. Mey, A. R., and S. M. Payne. 2001. Haem utilization in Vibrio cholerae involves multiple TonB-dependent haem receptors. Mol. Microbiol. 42:835-849.
27. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
28. Mills, M., and S. M. Payne. 1997. Identification of shuA, the gene encoding the heme receptor of Shigella dysenteriae, and analysis of invasion and intracellular multiplication of a shuA mutant. Infect. Immun. 65:5358-5363.
29. Occhino, D. A., E. E. Wyckoff, D. P. Henderson, T. J. Wrona, and S. M. Payne. 1998. Vibrio cholerae iron transport: haem transport genes are linked to one of two sets of tonB, exbB, exbD genes. Mol. Microbiol. 29:1493-1507.
30. O'Malley, S. M., S. L. Mouton, D. A. Occhino, M. T. Deanda, J. R. Rashidi, K. L. Fuson, C. E. Rashidi, M. Y. Mora, S. M. Payne, and D. P. Henderson. 1999. Comparison of the heme iron utilization systems of pathogenic vibrios. J. Bacteriol. 181:3594-3598.
31. Panek, H., and M. R. O'Brian. 2002. A whole genome view of prokaryotic biosynthesis. Microbiology 148:2273-2282.
32. Ratledge, C., and L. G. Dover. 2000. Iron metabolism in pathogenic bacteria. Annu. Rev. Microbiol. 54:881-941.
33. Rose, R. E. 1988. The nucleotide sequence of pACYC177. Nucleic Acids Res. 16:356.
34. Sambrook, J., and D.W. Rusell. 2001. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
35. Sørensen, U. S. B., and J. L. Larsen. 1986. Serotyping of Vibrio anguillarum. Appl. Environ. Microbiol. 51:593-597.
36. Stojiljkovic, I., and K. Hantke. 1992. Hemin uptake system of Yersinia enterocolitica: similarities with the other TonB-dependent systems in Gram-negative bacteria. EMBO J. 11:4359-4367.
37. Stojiljkovic, I., and K. Hantke. 1994. Transport of haemin across the cytoplasmic membrane through a haemin-specific periplasmic binding-protein- dependent transport system in Yersinia enterocolitica. Mol. Microbiol. 13:719-432.
38. Stork, M., M. Di Lorenzo, T. J. Welch, L. M. Crosa, and J. H. Crosa. 2002. Plasmid-mediated iron uptake and virulence in Vibrio anguillarum. Plasmid 48:222-228.
39. Torres, A. G., and S. M. Payne. 1997. Haem iron-transport system in enterohaemorrhagic Escherichia coli O157:H7. Mol. Microbiol. 23:825-833.
40. Walker, J. E., M. Saraste, M. J. Runswick, and N. J. Gay. 1982. Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 1:945-951.
41. Wang, R. F., and S. R. Kushner. 1991. Construction of versatile low-copy-number vectors for cloning, sequencing, and gene expression in Escherichia coli. Gene 100:195-199.
42. Wilks, A., and M. P. Schmitt. 1998. Expression and characterization of a heme oxygenase (HmuO) from Corynebacterium diphtheriae. J. Biol. Chem. 273:837-841.
43. Wyckoff, E. E., M. Schmitt, A. Wilks, and S. M. Payne. 2004. HutZ is required for efficient heme utilization in Vibrio cholerae. J. Bacteriol. 186:4142-4151.
44. Zhu, W., A. Wilks, and I. Stojiljkovic. 2000. Degradation of heme in gram-negative bacteria: the product of the hemO gene of Neisseriae is a heme oxygenase. J. Bacteriol. 182:6783-6790.