Cannabinoids and intestinal motility: Welcome to CB 2 receptors

British Journal of Pharmacology

Volumn 142, Issue 8, 2004, Pages 1201-1202

  Izzo, Angelo A ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cannabinoid receptors; Cyclooxygenase; Inflammation; Intestinal motility; Intestine; Lipopolysaccharide (LPS)

Indexed keywords

1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID METHYL 2 PHENYLTHIOETHYL ESTER; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID DERIVATIVE; CANNABINOID RECEPTOR ANTAGONIST; INDOMETACIN; NITRIC OXIDE SYNTHASE; UNCLASSIFIED DRUG;

BIOACCUMULATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG TARGETING; ENTERITIS; HUMAN; INTESTINE MOTILITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW;

ANIMALS; CANNABINOIDS; GASTROINTESTINAL MOTILITY; HUMANS; RATS; RECEPTOR, CANNABINOID, CB2;

EID: 4444234226     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705890     Document Type: Review

References (5)

1. DE PETROCELLIS, L., CASCIO, M.G. & DI MARZO, V. (2004). The endocannabinoid system: a general view and latest additions. Br. J. Pharmacol., 141, 765-774.
2. DI CARLO, G. & IZZO, A.A. (2003). Cannabinoids for gastrointestinal diseases: potential therapeutic applications. Expert Opin. Investig. Drugs, 12, 39-49.
3. IHENETU, K., MOLLEMAN, A., PARSONS, M.E. & WHELAN, C.J. (2003). Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids. Eur. J. Pharmacol., 458, 207-215.
4. IZZO, A.A., CAPASSO, F., COSTAGLIOLA, A., BISOGNO, T., MARSICANO, G., LIGRESTI, A., MATIAS, I., CAPASSO, R., PINTO, L., BORRELLI, F., CECIO, A., LUTZ, B., MASCOLO, N. & DI MARZO, V. (2003). An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. Gastroenterology, 125, 765-774.
5. MATHISON, R., HO, W., PITTMAN, Q.J.M., DAVISON, J.S. & SHARKEY, K.A. (2004). Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats. Br J. Pharmacol., 142, 1247-1254.