Colour Doppler ultrasound predicts chemotherapy response, but not survival in paediatric osteosarcoma

Pediatric Radiology

Volumn 34, Issue 8, 2004, Pages 614-619

  Bramer, Jos A M ^a   Gubler, Feikje M ^b   Maas, Mario ^a   Bras, Hans ^a   de Kraker, Jan ^a   van der Eijken, Jan W ^a   Schaap, Gerard R ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b N   (Netherlands)

Author keywords

Child; Colour Doppler ultrasound; Long bone; Osteosarcoma; Primary neoplasm; Skeleton; Treatment effect

Indexed keywords

CISPLATIN; DOXORUBICIN; METHOTREXATE;

ADOLESCENT; ARTERY RESISTANCE; ARTICLE; BLOOD FLOW VELOCITY; BONE RESECTION; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; COLOR ULTRASOUND FLOWMETRY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DRUG RESPONSE; FEMALE; HISTOPATHOLOGY; HUMAN; INFANT; MALE; OSTEOSARCOMA; PREDICTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SOFT TISSUE TUMOR; STATISTICAL SIGNIFICANCE; TREATMENT PLANNING; ULTRASOUND SCANNER;

EID: 4444234203     PISSN: 03010449     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00247-004-1210-z     Document Type: Article

References (26)

1. Davis AM, Bell RS, Goodwin PJ (1994) Prognostic factors in osteosarcoma: a critical review. J Clin Oncol 12:423-431
2. van der Woude HJ, Bloem JL, van Oostayen JA, et al (1995) Treatment of high-grade bone sarcomas with neoadjuvant chemotherapy: the utility of sequential color Doppler sonography in predicting histopathologic response. AJR 165:125-133
3. Enneking WF (1986) A system of staging musculoskeletal neoplasms. Clin Orthop March (204):9-24
4. Winkler K, Beron G, Delling G, et al (1988) Neoadjuvant chemotherapy of osteosarcoma: results of a randomized cooperative trial (COSS-82) with salvage chemotherapy based on histological tumor response. J Clin Oncol 6:329-337
5. Fixsen JA (1983) Rotation-plasty. J Bone Joint Surg Br 65:529-530
6. Rosen G, Caparros B, Huvos AG, et al (1982) Preoperative chemotherapy for osteogenic sarcoma: selection of post-operative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer 49:1221-1230
7. Salzer-Kuntschik M, Delling G, Beron G, et al (1983) Morphological grades of regression in osteosarcoma after polychemotherapy - study COSS 80. J Cancer Res Clin Oncol 106[Suppl]:21-24
8. van der Woude HJ, Bloem JL, Schipper J, et al (1994) Changes in tumor perfusion induced by chemotherapy in bone sarcomas: color Doppler flow imaging compared with contrast-enhanced MR imaging and three-phase bone scintigraphy. Radiology 191:421-431
9. Fletcher BD (1991) Response of osteosarcoma and Ewing sarcoma to chemotherapy: imaging evaluation. AJR 157:825-833
10. Holscher HC, Hermans J, Nooy MA, et al (1996) Can conventional radiographs be used to monitor the effect of neoadjuvant chemotherapy in patients with osteogenic sarcoma? Skeletal Radiol 25:19-24
11. Carrasco CH, Charnsangavej C, Raymond AK, et al (1989) Osteosarcoma: angiographic assessment of response to preoperative chemotherapy. Radiology 170:839-842
12. Schillaci O, Spanu A, Scopinaro F, et al (2003) Technetium-99m tetrofosmin scintigraphy in pediatric osteogenic sarcoma. Oncol Rep 10:605-608
13. Erlemann R, Sciuk J, Bosse A, et al (1990) Response of osteosarcoma and Ewing sarcoma to preoperative chemotherapy: assessment with dynamic and static MR imaging and skeletal scintigraphy. Radiology 175:791-796
14. van der Woude HJ, Bloem JL, Hogendoorn PC (1998) Preoperative evaluation and monitoring chemotherapy in patients with high-grade osteogenic and Ewing's sarcoma: review of current imaging modalities. Skeletal Radiol 27:57-71
15. Gorlick R, Liao AC, Antonescu C, et al (2001) Lack of correlation of functional scintigraphy with (99m)technetium-methoxyisobutylisonitrile with histological necrosis following induction chemotherapy or measures of P-glycoprotein expression in high-grade osteosarcoma. Clin Cancer Res 7:3065-3070
16. Riebel T, Knop J, Winkler K, et al (1986) Comparative x-ray and nuclear medical studies of osteosarcomas to evaluate the effectiveness of preoperative chemotherapy (in German). ROFO Fortschr Geb Rontgenstr Nuklearmed 145:365-372
17. Hansmann HJ, Wunsch C, Darge K, et al (1998) Diagnostic imaging for therapy control of primary bone tumors (in German). Radiologe 38:523-529
18. Knop J, Delling G, Heise U, et al (1990) Scintigraphic evaluation of tumor regression during preoperative chemotherapy of osteosarcoma. Correlation of (99m)Tc-methylene diphosphonate parametric imaging with surgical histopathology. Skeletal Radiol 19:165-172
19. Schulte M, Brecht-Krauss D, Werner M et al (1999) Evaluation of neoadjuvant therapy response of osteogenic sarcoma using FDG PET. J Nucl Med 40:1637-1643
20. Hawkins DS, Rajendran JG, Conrad EU III, et al (2002) Evaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-D-glucose positron emission tomography. Cancer 94:3277-3284
21. Franzius C, Bielack S, Flege S, et al (2002) Prognostic significance of (18)FFDG and (99m)Tc-methylene diphosphonate uptake in primary osteosarcoma. J Nucl Med 43:1012-1017
22. Bonnerot V, Charpentier A, Frouin F, et al (1992) Factor analysis of dynamic magnetic resonance imaging in predicting the response of osteosarcoma to chemotherapy. Invest Radiol 27:847-855
23. Fletcher BD, Hanna SL, Fairclough DL, et al (1992) Pediatric musculoskeletal tumors: use of dynamic, contrast-enhanced MR imaging to monitor response to chemotherapy. Radiology 184:243-248
24. Lang P, Vahlensieck M, Matthay KK, et al (1996) Monitoring neovascularity as an indicator of response to chemotherapy in osteogenic and Ewing sarcoma using magnetic resonance angiography. Med Pediatr Oncol 26:329-333
25. Ongolo-Zogo P, Thiesse P, Sau J, et al (1999) Assessment of osteosarcoma response to neoadjuvant chemotherapy: comparative usefulness of dynamic gadolinium-enhanced spin-echo magnetic resonance imaging and technetium-99m skeletal angioscintigraphy. Eur Radiol 9:907-914
26. Dyke JP, Panicek DM, Healey JH, et al (2003) Osteogenic and Ewing sarcomas: estimation of necrotic fraction during induction chemotherapy with dynamic contrast-enhanced MR imaging. Radiology 228:271-278