The effect of penetration enhancers on drug delivery through skin: A QSAR study

Journal of Controlled Release

Volumn 99, Issue 1, 2004, Pages 113-125

  Ghafourian, Taravat ^a,b,c   Zandasrar, Parinaz ^a   Hamishekar, Hamed ^a,b   Nokhodchi, Ali ^c  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Enhancer; Hydrophobicity; Lipophilicity; Penetration enhancer; Permeation enhancer; QSAR; Skin absorption; Transdermal penetration; Transdermal permeation

Indexed keywords

INTERMOLECULAR INTERACTIONS; PENETRATION RATE; SKIN PERMEATION;

DERIVATIVES; DRUG DOSAGE; DRUG INTERACTIONS; HYDROPHOBICITY; MOLECULAR DYNAMICS;

SKIN;

2 PYRROLIDONE DERIVATIVE; 3 CARENE; ASCARIDOLE; BENAZEPRIL; BISABOLOL; CARVEOL; CINEOLE; CYMENE; DICLOFENAC; DRUG VEHICLE; ESTRADIOL; FARNESOL; FLUOROURACIL; GERANIOL; HYDROCORTISONE; MENTHOL; MENTHONE; N ACETYLPROLINATE DERIVATIVE; NEROLIDOL; OCTANOL; PHYTOL; PIPERITONE; PROLINE DERIVATIVE; PULEGONE; PYRROLIDINE DERIVATIVE; TERPINEN 4 OL; TERPINEOL; THYMOL; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERBENONE;

ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULARY; DRUG PENETRATION; DRUG STRUCTURE; ELECTRON; HUMAN; HUMAN TISSUE; PARTITION COEFFICIENT; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SKIN PENETRATION; SKIN PERMEABILITY;

ADMINISTRATION, CUTANEOUS; ANIMALS; BENZAZEPINES; DICLOFENAC; ESTRADIOL; FLUOROURACIL; HUMANS; HYDROCORTISONE; MICE; MICE, INBRED HRS; MOLECULAR STRUCTURE; PROLINE; PYRROLIDINONES; SKIN ABSORPTION; STRUCTURE-ACTIVITY RELATIONSHIP; TERPENES;

EID: 4444227188     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.06.010     Document Type: Article

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