Synthesis and cytotoxicity study of alkannin derivatives

European Journal of Medicinal Chemistry

Volumn 39, Issue 9, 2004, Pages 755-764

  Huang, Zhi Shu ^a   Wu, Hai Qiang ^a   Duan, Zhi Fang ^a   Xie, Bing Fen ^a   Liu, Zong Chao ^a   Feng, Gong Kan ^a   Gu, Lian Quan ^a   Chan, Albert S C ^b   Li, Yue Ming ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

, Dimethylacrylalkannin; Alkannin derivatives; Conjugated addition; Cytotoxicity; Reductive alkylation

Indexed keywords

(2,2 DIMETHYLACRYL)ALKANNIN; 11 PHENYLSULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 2 DIMETHYLAMINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 2 METHYLPHENYLAMINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 2 MORPHOLINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 2 PHENYLAMINO 11 PHENYLSULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 2 PHENYLAMINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 2,11 BIS(METHOXYCARBONYL)CARBONYLSULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 2,11 BIS(MORPHOLINO) 6 ISOHEXENYLNAPHTHAZARIN; 2,11 BIS(PHENYLAMINO) 6 ISOHEXENYLNAPHTHAZARIN; 2,3,11 TRIETHANESULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 2,3,11 TRIMETHOXYCARBONYLMETHANESULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 2,3,11 TRIS(2 HYDROXYETHANESULFANYL) 6 ISOHEXENYLNAPHTHAZARIN; 2,3,7,11 TETRAETHANESULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 3 (2 HYDROXYETHANESULFANYL) 6 (11 BETA,BETA DIMETHYLACRYL) ISOHEXENYLNAPHTHAZARIN; 3 DIMETHYLAMINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 3 METHYLPHENYLAMINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 3 MORPHOLINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 3 PHENYLAMINO 11 PHENYLSULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 3 PHENYLAMINO 6 (11 BETA,BETA DIMETHYLACRYL)ISOHEXENYLNAPHTHAZARIN; 3,11 BIS(2 HYDROXYETHANESULFANYL) 6 ISOHEXENYLNAPHTHAZARIN; 3,11 BIS(METHOXYCARBONYL)CARBONYLSULFANYL 6 ISOHEXENYLNAPHTHAZARIN; 3,11 BIS(MORPHOLINO) 6 ISOHEXENYLNAPHTHAZARIN; 3,11 BIS(PHENYLAMINO) 6 ISOHEXENYLNAPHTHAZARIN; 3,11 BIS(PHENYLSULFANYL) 6 ISOHEXENYLNAPHTHAZARIN; 3,11 DIETHANESULFANYL 6 ISOHEXENYLNAPHTHAZARIN; ALKANNIN; ANTINEOPLASTIC AGENT; ISOHEXENYLNAPHTHAZARIN; UNCLASSIFIED DRUG;

ARNEBIA EUCHROMA; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG ISOLATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MEDICINAL PLANT; PLANT ROOT;

BORAGINACEAE; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; NAPHTHOQUINONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 4444222797     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.05.004     Document Type: Article

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