Differential effects comparing exercise and pharmacologic stress on left ventricular function using gated Tc-99m sestamibi SPECT

Annals of Nuclear Medicine

Volumn 22, Issue 3, 2008, Pages 185-190

  Ohtaki, Yuka ^a   Chikamori, Taishiro ^a   Igarashi, Yuko ^a   Hida, Satoshi ^a   Tanaka, Hirokazu ^a   Hatano, Tsuguhisa ^a   Usui, Yasuhiro ^a   Miyagi, Manabu ^a   Yamashina, Akira ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Myocardial stunning; Normalcy; Quantitative gated single photon emission computed tomography; Transient ischemic dilation

Indexed keywords

ADENOSINE TRIPHOSPHATE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY RISK; EXERCISE TEST; FEMALE; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDDSYSTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE VOLUME; HEART MUSCLE ISCHEMIA; HEART POSTISCHEMIC STUNNING; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PHARMACOLOGIC STRESS TESTING; PRIORITY JOURNAL; REST; STUNNED HEART MUSCLE;

ADENOSINE TRIPHOSPHATE; AGED; CORONARY ARTERY DISEASE; EXERCISE TEST; FEMALE; GATED BLOOD-POOL IMAGING; HUMANS; MALE; MATCHED-PAIR ANALYSIS; MIDDLE AGED; MYOCARDIAL STUNNING; RADIOPHARMACEUTICALS; REST; RETROSPECTIVE STUDIES; STRESS; STROKE VOLUME; TECHNETIUM TC 99M SESTAMIBI; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VENTRICULAR FUNCTION, LEFT;

EID: 44349189365     PISSN: 09147187     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12149-007-0106-z     Document Type: Article

References (35)

1. Smanio PE, Watson DD, Segalla DL, Vinson EL, Smith WH, Beller GA. Value of gating of technetium-99m sestamibi single-photon emission computed tomographic imaging. J Am Coll Cardiol 1997;30:1687-1692.
2. Sharir T, Germano G, Kavanagh PB, Lai S, Cohen I, Lewin HC, et al. Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography. Circulation 1999;100:1035-1042.
3. Sharir T, Germano G, Kang X, Lewin HC, Miranda R, Cohen I, et al. Prediction of myocardial infarction versus cardiac death by gated myocardial perfusion SPECT: risk stratification by the amount of stress-induced ischemia and the post-stress ejection fraction. J Nucl Med 2001;42:831-837.
4. Lima RS, Watson DD, Goode AR, Siadaty MS, Ragosta M, Beller GA, et al. Incremental value of combined perfusion and function over perfusion alone by gated SPECT myocardial perfusion imaging for detection of severe three-vessel coronary artery disease. J Am Coll Cardiol 2003;42:64-70.
5. Abidov A, Germano G, Hachamovitch R, Berman DS. Gated SPECT in assessment of regional and global left ventricular function: major tool of modern nuclear imaging. J Nucl Cardiol 2006;13:261-279.
6. Johnson LL, Verdesca SA, Aude WY, Xavier RC, Nott LT, Campanella MW, et al. Postischemic stunning can affect left ventricular ejection fraction and regional wall motion on post-stress gated sestamibi tomograms. J Am Coll Cardiol 1997;30:1641-1648.
7. Sharir T, Bacher-Stier C, Dhar S, Lewn HC, Miranda R, Friedman JD, et al. Identification of severe and extensive coronary artery disease by postexercise regional wall motion abnormalities in Tc-99m sestamibi gated single-photon emission computed tomography. Am J Cardiol 2000;86:1171-1175.
8. Bestitti A, Di Leo C, Alessi A, Triulzi A, Tagliabue L, Tarolo GL. Post-stress end-systolic left ventricular dilation: a marker of endocardial post ischemic stunning. Nucl Med Commun 2001;22:685-693.
9. Emmett L, Iwanochko RM, Freeman MR, Barolet A, Lee DS, Husain M. Reversible regional wall motion abnormalities on exercise technetium-99m-gated cardiac single photon emission computed tomography predict high-grade angiographic stenosis. J Am Coll Cardiol 2002;39:991-998.
10. Mclaughlin MG, Danias PG. Transient ischemic dilatation: a powerful diagnostic and prognostic finding of stress myocardial perfusion imaging. J Nucl Cardiol 2002;9:663-667.
11. Heston TF, Sigg DM. Quantifying transient ischemic dilation using gated SPECT. J Nucl Med 2005;46:1990-1996.
12. Druz RS, Akinboboye OA, Grimson R, Nichols KJ, Reichek N. Postischemic stunning after adenosine vasodilator stress. J Nucl Cardiol 2004;11:534-541.
13. Hida S, Chikamori T, Tanaka H, Usui Y, Igarashi Y, Nagao T, et al. Diagnostic value of left ventricular function after stress and at rest in the detection of multivessel coronary artery disease as assessed by electrocardiogram-gated SPECT. J Nucl Cardiol 2007;14:68-74.
14. Paul AK, Hasegawa S, Yoshida J, Mu X, Maruyama K, Kusuoka H. Characteristics of regional myocardial stunning after exercise in gated myocardial SPECT. J Nucl Cardiol 2002;9:388-394.
15. Hung GU, Lee KW, Chen CP, Yang KT, Lin WY. Worsening of left ventricular ejection fraction induced by dipyridamole on Tl-201 gated myocardial perfusion imaging predicts significant coronary artery disease. J Nucl Cardiol 2006;13:225-232.
16. Lee DS, Yeo JS, Chung JK, Lee MM, Lee MC. Transient prolonged stunning induced by dipilidamole and shown on 1-and 24-hour poststress 99mTc-MIBI gated SPECT. J Nucl Med 2000;41:27-35.
17. Tanaka H, Chikamori T, Hida S, Usui Y, Harafuji K, Igarashi Y, et al. Comparison of post-exercise and post-vasodilator stress myocardial stunning as assessed by electrocardiogramgated single photon emission computed tomography. Circ J 2005;69:1338-1345.
18. Ward RP, Gundeck EL, Lang RM, Spencer KT, Williams KA. Overestimation of postischemic myocardial stunning on gated SPECT imaging: correlation with echocardiography. J Nucl Cardiol 2006;13:514-520.
19. Manrique A, Faraggi M, Véra P, Vilain D, Lebtahi R, Cribier A, et al. 201Tl and 99mTc-MIBI gated SPECT in patients with large perfusion defects and left ventricular dysfunction: comparison with equilibrium radionuclide angiography. J Nucl Med 1999;40:805-809.
20. Manrique A, Hitzel A, Brasse D, Vera P. Effect of perfusion pattern and imaging sequence on gated perfusion SPECT evaluation of myocardial stunning. J Nucl Med 2005;46:176-183.
21. Heo J, Kegel J, Iskandrian AS, Cave V, Iskandrian BB. Comparison of same-day protocols using technetium-99m-sestamibi myocardial imaging. J Nucl Med 1992;33:186-191.
22. Hida S, Chikamori T, Hirayama T, Usui Y, Yanagisawa H, Morishima T, et al. Beneficial effect of coronary artery bypass grafting as assessed by quantitative gated single-photon emission computed tomography. Circ J 2003;67:1144-1154.
23. Hida S, Chikamori T, Usui Y, Yanagisawa H, Morishima T, Yamashina A. effect of percutaneous coronary angioplasty on myocardial perfusion, function, and wall thickness as assessed by quantitative gated single-photon emission computed tomography. Am J Cardiol 2003;91:591-594.
24. Hachamovitch R, Berman DS, Kiat H, Cohen I, Cabico JA, Friedman J, et al. Exercise myocardial perfusion SPECT in patients without known coronary artery disease: incremental prognostic value and use in risk stratification. Circulation 1996;93:905-914.
25. Leslie WD, Tully SA, Yogendran MS, Ward LM, Nour KA, Metge CJ. Prognostic value of automated quantification of 99mTc-sestamibi myocardial perfusion imaging. J Nucl Med 1995;46:204-211.
26. Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su HT, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med 1995;36:2138-2147.
27. Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, et al. A reporting system on patients evaluated for coronary artery disease: report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 1975;51Suppl 4:5-40.
28. Mann DL, Denenberg BS, Gash AK, Makler PT, Bove AA. Effects of age on ventricular performance during graded supine exercise. Am Heart J 1986;111:108-115.
29. Rodeheffer RJ, Gerstenblith G, Becker LC, Fleg JL, Weisfeldt ML, Lakatta EG. Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate. Circulation 1984;69:203-213.
30. Vogel WM, Apstein CS, Briggs LL, Gaasch WH, Ahn J. Acute alternations in left ventricular diastolic chamber stiffness: role of the "erectile" effect of coronary arterial pressure and flow in normal and damaged hearts. Circ Res 1982;51:465-478.
31. Ogilby JD, Iskandrian AS, Untereker WJ, Heo J, Nguyen TN, Mercuro J. Effect of intravenous adenosine infusion on myocardial perfusion and function: hemodynamic/angiographic and scintigraphic study. Circulation 1992;86:887-895.
32. Nussbacher A, Arie S, Kalil R, Horta P, Feldman MD, Bellotti G, et al. Mechanism of adenosine induced elevation of pulmonary capillary wedge pressure in humans. Circulation 1995;92:371-379.
33. Abidov A, Bax JJ, Hayes SW, Hachamovitch R, Cohen I, Gerlach J, et al. Transient ischemic dilation ratio of the left ventricle is a significant predictor of future cardiac events in patients with otherwise normal myocardial perfusion SPECT. J Am Coll Cardiol 2003;42:1818-1825.
34. Heiba SI, Santiago J, Mirzaitehrane M, Jana S, Dede F, Abdel-Dayem HM. Transient postischemic stunning evaluation by stress gated Tl-201 SPECT myocardial imaging: effect on systolic left ventricular function. J Nucl Cardiol 2002;9:482-490.
35. Nagao T, Chikamori T, Hida S, Igarashi Y, Kuwabara Y, Nishimura S, et al. Quantitative gated single-photon emission computed tomography with Tc-99m sestamibi predicts major cardiac events in elderly patients with known or suspected coronary artery disease: QGS-prognostic value in the elderly (Q-PROVE) study. Circ J 2007;71:1029-1034.