Frailty in Parkinson's disease and its clinical implications

Parkinsonism and Related Disorders

Volumn 14, Issue 4, 2008, Pages 334-337

  Ahmed, Nasiya N ^a,b   Sherman, Scott J ^b   VanWyck, David ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Frailty; Geriatrics; Parkinson's disease

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DISEASE SEVERITY; ENERGY EXPENDITURE; EXHAUSTION; FEMALE; FRAIL ELDERLY; GRIP STRENGTH; HUMAN; MALE; PARKINSON DISEASE; PRIORITY JOURNAL; UNIFIED PARKINSON DISEASE RATING SCALE; WEIGHT REDUCTION;

AMBULATORY CARE; CROSS-SECTIONAL STUDIES; ENERGY INTAKE; FEMALE; HAND STRENGTH; HUMANS; MALE; NEUROLOGIC EXAMINATION; OBSERVATION; PARKINSON DISEASE; PREVALENCE; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; WALKING; WEIGHT LOSS;

EID: 44349159771     PISSN: 13538020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2007.10.004     Document Type: Article

References (20)

1. de Lau L.M., and Breteler M.M. Epidemiology of Parkinson's disease. Lancet Neurol 5 6 (2006) 525-535
2. Fried L.P. Frailty. In: Cassel C., Leipzig R., Cohen H., et al. (Eds). Geriatric medicine: an evidence-based approach (2003), Springer, New York 1067-1074
3. Walston J., McBurnie M.A., Newman A., Tracy R.P., Kop W.J., Hirsch C.H., et al. Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med 162 20 (2002) 2333-2341
4. Puts M.T., Lips P., and Deeg D.J. Sex differences in the risk of frailty for mortality independent of disability and chronic diseases. J Am Geriatr Soc 53 1 (2005) 40-47
5. Fried L.P., Tangen C.M., Walston J., Newman A.B., Hirsch C., Gottdiener J., et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56 3 (2001) M146-M156
6. Newman A.B., Gottdiener J.S., McBurnie M.A., Hirsch C.H., Kop W.J., Tracy R.P., et al. Associations of subclinical cardiovascular disease with frailty. J Gerontol A Biol Sci Med Sci 56 3 (2001) M158-M166
7. Klein B.E., Klein R., Knudtson M.D., and Lee K.E. Frailty, morbidity and survival. Arch Gerontol Geriatr 41 2 (2005) 141-149
8. Binder E.F., Schechtman K.B., Ehsani A.A., Steger-May K., Brown M., Sinacore D.R., et al. Effects of exercise training on frailty in community-dwelling older adults: results of a randomized, controlled trial. J Am Geriatr Soc 50 12 (2002) 1921-1928
9. Wolf S.L., Sattin R.W., Kutner M., O'Grady M., Greenspan A.I., and Gregor R.J. Intense tai chi exercise training and fall occurrences in older, transitionally frail adults: a randomized, controlled trial. J Am Geriatr Soc 51 12 (2003) 1693-1701
10. Fahn S., and Elton R.L. Unified Parkinson's disease rating scale. In: Fahn S., Marsden C.D., Calne D.B., et al. (Eds) (1987), Macmillan Health Care Information, Florham Park, NJ 153-164
11. Radloff L.S. A self report depression scale for research in the general population. Appl Psychol Meas 1 (1977) 385-401
12. Promoting physical activity: a guide for community action. Human kinetics. Champaign, IL: US Department of Health and Human Services Centers for Disease Control and Prevention; 1993.
13. Uc E.Y., Struck L.K., Rodnitzky R.L., Zimmerman B., Dobson J., Evans W.J., et al. Predictors of weight loss in Parkinson's disease. Mov Disord 21 7 (2006) 930-936
14. Lorefalt B., Ganowiak W., Palhagen S., Toss G., Unosson M., Granerus A.K., et al. Factors of importance for weight loss in elderly patients with Parkinson's disease. Acta Neurol Scand 110 3 (2004) 180-187
15. Chen H., Zhang S.M., Hernan M.A., Willett W.C., and Ascherio A. Weight loss in Parkinson's disease. Ann Neurol 53 5 (2003) 676-679
16. Vieregge P., Stolze H., Klein C., and Heberlein I. Gait quantitation in Parkinson's disease-locomotor disability and correlation to clinical rating scales. J Neural Transm 104 2/3 (1997) 237-248
17. Lou J.S., Kearns G., Oken B., Sexton G., and Nutt J. Exacerbated physical fatigue and mental fatigue in Parkinson's disease. Mov Disord 16 2 (2001) 190-196
18. Leng S., Chaves P., Koenig K., and Walston J. Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study. J Am Geriatr Soc 50 7 (2002) 1268-1271
19. Rockwood K., and Mitnitski A. Frailty in relation to the accumulation of deficits. J Gerontol A Biol Sci Med Sci 62 7 (2007) 722-727
20. Rockwood K., Andrew M., and Mitnitski A. A comparison of two approaches to measuring frailty in older people. J Gerontol A Biol Sci Med Sci 62 7 (2007) 738-743