Progress Toward Personalized Medicine for Age-related Macular Degeneration

Ophthalmology

Volumn 115, Issue 6, 2008, Pages 925-926

  Moroi, Sayoko E ^a   Heckenlively, John R ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BEVACIZUMAB; MITOCHONDRIAL DNA; ZINC;

ALCOHOL CONSUMPTION; CLINICAL EXAMINATION; CLINICAL PRACTICE; DISEASE COURSE; EDITORIAL; GENE MUTATION; GENETIC ANALYSIS; GENETIC MARKER; GENETIC VARIABILITY; HEALTH BEHAVIOR; HUMAN; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING;

DELIVERY OF HEALTH CARE; GENE EXPRESSION PROFILING; GENETIC MARKERS; HUMANS; MACULAR DEGENERATION; PERSONAL HEALTH SERVICES; PHARMACOGENETICS; RISK FACTORS;

EID: 44349150866     PISSN: 01616420     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ophtha.2008.04.020     Document Type: Editorial

References (12)

1. Botstein D., and Risch N. Discovering genotypes underlying human phenotypes: past successes for Mendelian disease, future approaches for complex disease. Nat Genet 33 suppl (2003) 228-237
2. Kingsmore S.F., Lindquist I.E., Mudge J., et al. Genome-wide association studies: progress and potential for drug discovery and development. Nat Rev Drug Discov 7 (2008) 221-230
3. Montezuma S.R., Sobrin L., and Seddon J.M. Review of genetics in age related macular degeneration. Semin Ophthalmol 22 (2007) 229-240
4. Despriet D.D., Klaver C.C., van Duijn C.C., and Janssens A.C. Predictive value of multiple genetic testing for age-related macular degeneration. Arch Ophthalmol 125 (2007) 1270-1271
5. Klein M.L., Francis P.J., Rosner B., et al. CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. Ophthalmology 115 (2008) 1019-1025
6. Brockmoller J., and Tzvetkov M.V. Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. Eur J Clin Pharmacol 64 (2008) 133-157
7. Brantley Jr. M.A., Fang A.M., King J.M., et al. Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab. Ophthalmology 114 (2007) 2168-2173
8. Gage B.F., and Lesko L.J. Pharmacogenetics of warfarin: regulatory, scientific, and clinical issues. J Thromb Thrombolysis 25 (2008) 45-51
9. Newsome D.A., Swartz M., Leone N.C., et al. Oral zinc in macular degeneration. Arch Ophthalmol 106 (1988) 192-198
10. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Arch Ophthalmol 119 (2001) 1417-1436
11. Coleman H., and Chew E. Nutritional supplementation in age-related macular degeneration. Curr Opin Ophthalmol 18 (2007) 220-223
12. Schaumberg D.A., Hankinson S.E., Guo Q., et al. A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors. Arch Ophthalmol 125 (2007) 55-62