Tolerance to disulfiram induced by chronic alcohol intake in the rat

Alcoholism: Clinical and Experimental Research

Volumn 32, Issue 6, 2008, Pages 937-941

  Tampier, Lutske ^a   Quintanilla, María Elena ^a   Israel, Yedy ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

Disulfiram; Diversion; Ethanol; Reward; Tolerance

Indexed keywords

ACETALDEHYDE; ALCOHOL; CYANAMIDE; DISULFIRAM;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RAT; WISTAR RAT;

ACETALDEHYDE; ALCOHOL DEHYDROGENASE; ALCOHOL DETERRENTS; ALCOHOL DRINKING; ALCOHOLISM; ANIMALS; CYANAMIDE; DISULFIRAM; DRUG TOLERANCE; ENZYME INHIBITORS; ETHANOL; FEMALE; RATS; RATS, WISTAR;

ANIMALIA; RATTUS;

EID: 44349126635     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2008.00658.x     Document Type: Article

References (48)

1. Agabio R, Cortis G, Fadda F, Gessa GL, Lobina C, Reali R, Colombo G (1996) Drinking pattern of Sardinian alcohol preferring rats. Alcohol Alcohol 31 : 385 388.
2. Amit Z, Brown ZW, Rockman GE (1977) Possible involvement of acetaldehyde, norepinephrine and their tetrahydroisoquinoline derivatives in the regulation of ethanol seld-administration. Drug Alcohol Depend 5-6 : 495 500.
3. Aragon CM, Amit Z (1992) The effect of 3-amino-1,2,4-triazole on voluntary ethanol consumption: evidence for brain catalase involvement in the mechanism of action. Neuropharmacology 31 : 709 712.
4. Aragon CM, Rowan F, Amit Z (1992) Ethanol metabolism in rat brain homogenates by a catalase-H2O2 system. Biochem Pharmacol 44 : 93 98.
5. Beyeler C, Fisch HU, Preisig R (1985) The disulfiram-alcohol reaction: factors determining and potential tests predicting severity. Alcohol Clin Exp Res 9 : 118 124.
6. Brewer C (1984) How effective is the standard dose of disulfiram? Brit J Psychiatry 144 : 1310.
7. Brown ZW, Amit Z, Rockman GE (1979) Intraventricular self-administration of acetaldehyde, but not ethanol, in naive laboratory rats. Psychopharmacology (Berl) 64 : 271 276.
8. Brown ZW, Amit Z, Smith B (1980) Intraventricular self-administration of acetaldehyde and voluntary consumption of ethanol in rats. Behav Neural Biol 28 : 150 155.
9. Chen CC, Lu RB, Chen YC, Wang MF, Chang YC, Li TK, Yin SJ (1999) Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism. Am J Hum Genet 65 : 795 807.
10. Chick J, Gough K, Kershaw P, Hore B, Mehta B, Ritson B, Ropner R, Torley B (1992) Disulfiram treatment of alcoholism. Br J Psychiatry 161 : 84 89.
11. Christensen JK, Moller IW, Ronsted R, Angelo HR, Johansson BJ (1991) Dose-effect relationship of disulfiram in human volunteers. J Pharmacol Toxicol 68 : 163 165.
12. Collins AC, Marks MJ (1995) Animal models of alcohol-nicotine interactions, in Alcohol and Tobacco (Fertig JB, Allen JP eds pp 129 144. From Basic Science to Clinical Practice NIAAA Research Monograph #30, Bethesda, MD.
13. De Sousa A, de Sousa A (2005) An open randomized study comparing disulfiram and acamprosate in the treatment of alcohol dependence. Alcohol Alcohol 40 : 545 548.
14. Dupuy O, Flocard F, Vial C, Rode G, Carles N, Boisson D, Flechaire A (1995) Disulfiram toxicity. Rev Med Interne 16 : 67 72.
15. Fuller RK, Branchey L, Brightwell DR, Derman RM, Emrick CD, Iber FL, James KE, Lacoursiere RB, Lee KK, Lowenstam I (1986) Disulfiram treatment of alcoholism. A Veterans Administration cooperative study. JAMA 256 : 1449 1455.
16. Fuller RK, Gordis E (2004) Does disulfiram have a role in alcoholism treatment today? Addiction 99 : 21 24.
17. Gallant DM (1987) The use of psychopharmacologic medications in alcoholism. in Alcoholism: A Guide to Diagnosis, Intervention and Treatment (Gallant DM ed. pp 170. W.W. Norton & Company, New York, London.
18. Garver E, Tu GC, Cao QN, Aini M, Zhou F, Israel Y (2001) Eliciting the low-activity aldehyde dehydrogenase Asian phenotype by an antisense mechanism results in an aversion to ethanol. J Exp Med 194 : 571 580.
19. Harada S, Agarwal DP, Goedde HW, Tagaki S, Ishikawa B (1982) Possible protective role against alcoholism for aldehyde dehydrogenase isozyme deficiency in Japan. Lancet 2 : 827.
20. Hellstrom E, Tottmar O (1982) Effects of aldehyde dehydrogenase inhibitors on enzymes involved in the metabolism of biogenic aldehydes in rat liver and brain. Biochem Pharmacol 31 : 3899 3905.
21. Hurt RD, Eberman KM, Croqhan IT, Oxford KP, Davies LJ, Morse RM, Palmen MA, Bruce BK (1994) Nicotine dependence treatment during inpatient treatment for other addictions: a prospective intervention trial. Alcohol Clin Exp Res 18 : 867 872.
22. Jamal M, Ameno K, Uekita I, Kumihashi M, Wang W, Ijiri I (2007) Catalase mediates acetaldehyde formation in the striatum of free-moving rats. Neurotoxicology 28 : 1245 1248.
23. Joshi M, Tyndale RF (2006) Induction and recovery time course of rat brain CYP2E1 after nicotine treatment. Drug Metab Disposition 34 : 647 652.
24. Koechling UM, Amit Z (1994) Effects of 3-amino-1,2,4-triazole on brain catalase in the mediation of ethanol consumption in mice. Alcohol 11 : 235 239.
25. Laaksonen E, Koski-Jannes A, Salaspuro M, Ahtinen H, Alho H (2007) A randomized, multicentre, open-label, comparative trial of disulfiram, nalterexone and acamprosate in the treatment of alcohol dependence. Alcohol Alcohol 43 : 53 61.
26. Lessov CN, Risinger FO, Phillips TJ (2001) Attenuation of ethanol-induced conditioned taste aversion in mice sensitized to the locomotor stimulant effects of ethanol. Behav Neurosci 115 : 146 153.
27. Li TK (2000) Pharmacogenetics of responses to alcohol and genes that influence drinking. J Stud Alcohol 61 : 5 12.
28. Madan A, Faiman MD (1995) Characterization of diethyl dithio carbamate methylester sulfine as an intermediate in the bioactivation of disulfiram. J Pharmacol Exp Ther 272 : 775 780.
29. Mark TL, Kranzler HR, Song X, Bransberger P, Poole VH, Crosse S (2003) Physicians' opinions about medications to treat alcoholism. Addiction 98 : 617 626.
30. Mays DC, Nelson AN, Fauq AH, Schriver ZH, Ververka KA (1995) S-methyl N,N diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase. Biochem Pharmacol 49 : 693 700.
31. Ocaranza P, Quintanilla ME, Tampier L, Karahanian E, Sapag A, Israel Y (2008) Gene therapy reduces ethanol intake in an animal model of alcohol dependence. Alcohol Clin Exp Res (in press).
32. Peachey JE, Annis H (1989) Effectiveness of aversion therapy using disulfiram and related compounds, in Human Metabolism of Alcohol Vol I (Crow KE, Batt RD eds pp 158 167. CRC Press, Boca Raton, FL.
33. Peachey JE., Brien JF, Loomis CW, Rogers BJ (1980) A study of the calcium carbimide-ethanol interaction in man: symptom responses. Alcohol Clin Exp Res 4 : 322 329.
34. Quertemont E (2004) Genetic polymorphism in ethanol metabolism: acetaldehyde contribution to alcohol abuse and alcoholism. Mol Psychiatry 9 : 570 581.
35. Quertemont E, de Witte P (2001) Conditioned stimulus preference after acetaldehyde but not ethanol injections. Pharmacol Biochem Behav 68 : 449 454.
36. Quintanilla ME, Israel Y, Sapag A, Tampier L (2006) The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake. Addict Biol 11 : 310 323.
37. Quintanilla ME, Tampier L (2003) Acetaldehyde-reinforcing effects: differences in low-alcohol-drinking (UChA) and high-alcohol-drinking (UChB) rats. Alcohol 31 : 63 69.
38. Quintanilla ME, Tampier L, Sapag A, Gerdtzen Z, Israel Y (2007) Sex, alcohol dehydrogenase, acetaldehyde burst and aversion to ethanol in the rat: a systems perspective. Am J Physiol Endocrinol Metab 293 : E531 E537.
39. Robinson TE, Berridge KC (1993) The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 18 : 247 291. Review.
40. Rodd-Henriks ZA, Melendez RI, Zaffaroni A, Goldstein A, McBride WJ, Li TK (2002) The reinforcing effects of acetaldehyde in the posterior ventral tegmental area of alcohol-preferring rats. Pharmacol Biochem Behav 72 : 55 64.
41. Tampier L, Quintanilla ME (2002) Effect of acetaldehyde on acute tolerance and ethanol consumption in drinker and nondrinker rats. J Stud Alcohol 63 : 257 262.
42. Tampier L, Quintanilla ME (2003) Involvement of brain ethanol metabolism on acute tolerance development and on ethanol consumption in alcohol-drinker (UChB) and non-drinker (UChA) rats. Addict Biol 8 : 279 286.
43. Tampier L, Quintanilla ME, Mardones J (1995) Effects of aminotriazole on ethanol, water and food intake and on brain catalase in UChA and UChB rats. Alcohol 4 : 341 344.
44. Thomasson HR, Edenberg HJ, Crabb DW, Mai XL, Jerome RE, Li TK, Wang SP, Lin YT, Lu RB, Yin SJ (1991) Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 48 : 677 681.
45. Tu GC, Israel Y (1995) Alcohol consumption by Orientals in North America is predicted largely by a single gene. Behav Genet 25 : 59 65.
46. Vasiliou V, Ziegler TL, Bludeau P, Petersen DR, Gonzalez FJ, Deitrich RA (2006) CYP2E1 and catalase influence ethanol sensitivity in the central nervous system. Pharmacogenetics and Genomics 16 : 51 58.
47. Weiss RD, Kueppenbender KD (2006) Combining psychosocial treatment with pharmacotherapy for alcohol dependence. J Clin Psychopharmacol 26 (Suppl 1 S37 S42.
48. Zimatkin SM, Pronko SP, Vasilious V, Gonzalez F, Deitrich RA (2006) Enzymatic systems of ethanol oxidation in the brain. Alcohol Clin Exp Res 30 : 1500 1505.