Intrathecal baclofen bolus complicated by deep vein thrombosis and pulmonary embolism. A case report

European Journal of Physical and Rehabilitation Medicine

Volumn 44, Issue 1, 2008, Pages 87-88

  Carda, S ^a,b   Cazzaniga, M ^a   Taiana, C ^a   Pozzi, R ^a  

^a VALDUCE HOSPITAL   (Italy)

^b Pain Therapy Valduce Hospital ^*  (Italy)

Author keywords

Amyotrophic lateral sclerosis; Baclofen; Motor neuron disease; Muscle spasticity; Pulmonary embolism; Venous thrombosis

Indexed keywords

BACLOFEN; CENTRAL MUSCLE RELAXANT;

AGED; ARTICLE; CASE REPORT; CHEMICALLY INDUCED DISORDER; DIFFERENTIAL DIAGNOSIS; DOPPLER FLOWMETRY; ECHOCARDIOGRAPHY; FEMALE; HUMAN; INJECTION; LUNG EMBOLISM; MOTOR NEURON DISEASE; SPASTICITY; VEIN THROMBOSIS;

AGED; BACLOFEN; DIAGNOSIS, DIFFERENTIAL; ECHOCARDIOGRAPHY; FEMALE; HUMANS; INJECTIONS; MOTOR NEURON DISEASE; MUSCLE RELAXANTS, CENTRAL; MUSCLE SPASTICITY; PULMONARY EMBOLISM; ULTRASONOGRAPHY, DOPPLER; VENOUS THROMBOSIS;

EID: 44349104661     PISSN: 19739087     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Francisco GE. The role of intrathecal baclofen therapy in the upper motor neuron syndrome. Eura Medicophys 2004;40:131-43.
2. Delhaas EM, Brouwers JR. Intrathecal baclofen overdose: report of 7 events in 5 patients and review of the literature. Int J Clin Pharmacol Ther Toxicol 1991;29:274-80.
3. Ochs G, Struppler A, Meyerson BA Linderoth B, Gybels J, Gardner BP et al. Intrathecal baclofen for long-term treatment of spasticity: a multi-centre study. J Neurol Neurosurg Psychiatry 1989;52:933-9.
4. Murphy NA. Deep venous thrombosis as a result of hypotonia secondary to intrathecal baclofen therapy: a case report. Arch Phys Med Rehabil 2002;83:1311-2.
5. Blann AD, Lip GY. Wirchow's triad revisited: the importance of soluable coagulation factors, the endothelium and platelets. Thromb Res 2001;101:321-7
6. Rode G, Mertens P, Beneton C, Schmitt M, Boisson D. Regression of vasomotor disorders under intrathecal baclofen in a case of spastic paraplegia. Spinal Cord 1999;37:370-2
7. Elman LB, Siderowf A, Houseman G, Kelley M, McCluskey LF. Venous thrombosis in an ALS population over four years. Amyotroph Lateral Scler Other Motor Neuron Disord 2005;6:246-9.