Novel N-(phosphonomethyl) glycine derivatives: Design, characterization and biological activity

European Journal of Medicinal Chemistry

Volumn 43, Issue 6, 2008, Pages 1199-1205

  Naydenova, Emilia D ^a   Todorov, Petar T ^a   Topashka Ancheva, Margarita N ^b   Momekov, Georgi Ts ^c   Yordanova, Tsvetelina Z ^b   Konstantinov, Spiro M ^c   Troev, Kolio D ^d  

^a UNIVERSITY OF CHEMICAL TECHNOLOGY AND METALLURGY   (Bulgaria)

^b INSTITUTE OF BIODIVERSITY AND ECOSYSTEM RESEARCH   (Bulgaria)

^c MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^d INSTITUTE OF POLYMERS   (Bulgaria)

Author keywords

Aminophosphonic acids; Cell proliferation; Chromosome aberrations; Clastogenic effects; Cytotoxic activity; N (Phosphonomethyl) glycine derivatives

Indexed keywords

1 [(DIMETHOXYPHOSPHONO)METHYLAMINO]CYCLODODECANECARBOXYLIC ACID; 1 [(DIMETHOXYPHOSPHONO)METHYLAMINO]CYCLOHEPTANECARBOXYLIC ACID; 1 [(DIMETHOXYPHOSPHONO)METHYLAMINO]CYCLOHEXANECARBOXYLIC ACID; 1 [(DIMETHOXYPHOSPHONO)METHYLAMINO]CYCLOOCTANECARBOXYLIC ACID; 1 [(DIMETHOXYPHOSPHONO)METHYLAMINO]CYCLOPENTANECARBOXYLIC ACID; CISPLATIN; CLASTOGEN; GLYCINE DERIVATIVE; MITOMYCIN C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOLOGICAL ACTIVITY; BONE MARROW CELL; CANCER CELL CULTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; EMBRYO; FEMALE; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN;

APOPTOSIS; CELL LINE; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; GLYCINE; MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENS; SPECTROPHOTOMETRY, INFRARED;

EID: 44349093643     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.08.010     Document Type: Article

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