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Volumn 9, Issue , 2008, Pages

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E4; CHOLESTEROL; LUTEINIZING HORMONE BETA SUBUNIT; LUTEINIZING HORMONE RECEPTOR; NEUROSTEROID; STEROID;

EID: 44349083202     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-9-37     Document Type: Article
Times cited : (18)

References (60)
  • 1
    • 4043132373 scopus 로고    scopus 로고
    • The current status of Alzheimer's disease genetics: What do we tell the patients?
    • 10.1016/j.phrs.2003.11.018 15304236
    • Bertram L Tanzi RE The current status of Alzheimer's disease genetics: what do we tell the patients? Pharmacol Res 2004, 50:385-396 10.1016/ j.phrs.2003.11.018 15304236
    • (2004) Pharmacol Res , vol.50 , pp. 385-396
    • Bertram, L.1    Tanzi, R.E.2
  • 4
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
    • 10.1001/jama.278.16.1349 9343467
    • Farrer LA Cupples LA Haines JL Hyman B Kukull WA Mayeux R Myers RH Pericak-Vance MA Risch N van Duijn CM Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium Jama 1997, 278:1349-1356 10.1001/jama.278.16.1349 9343467
    • (1997) Jama , vol.278 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3    Hyman, B.4    Kukull, W.A.5    Mayeux, R.6    Myers, R.H.7    Pericak-Vance, M.A.8    Risch, N.9    van Duijn, C.M.10
  • 7
    • 33746013839 scopus 로고    scopus 로고
    • Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease
    • 10.1016/j.neurobiolaging.2005.07.013 16154235
    • Chapuis J Tian J Shi J Bensemain F Cottel D Lendon C Amouyel P Mann D Lambert JC Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease Neurobiol Aging 2006, 27:1212-1215 10.1016/j.neurobiolaging.2005.07.013 16154235
    • (2006) Neurobiol Aging , vol.27 , pp. 1212-1215
    • Chapuis, J.1    Tian, J.2    Shi, J.3    Bensemain, F.4    Cottel, D.5    Lendon, C.6    Amouyel, P.7    Mann, D.8    Lambert, J.C.9
  • 8
    • 33748194140 scopus 로고    scopus 로고
    • Lack of association of 5 SNPs in the vicinity of the insulin-degrading enzyme (IDE) gene with late-onset Alzheimer's disease
    • 10.1016/j.neulet.2006.07.054 16914266
    • Ozturk A DeKosky ST Kamboh MI Lack of association of 5 SNPs in the vicinity of the insulin-degrading enzyme (IDE) gene with late-onset Alzheimer's disease Neurosci Lett 2006, 406:265-269 10.1016/ j.neulet.2006.07.054 16914266
    • (2006) Neurosci Lett , vol.406 , pp. 265-269
    • Ozturk, A.1    DeKosky, S.T.2    Kamboh, M.I.3
  • 11
    • 27244443755 scopus 로고    scopus 로고
    • Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women
    • 10.1038/sj.ejhg.5201447 15944651
    • Pirskanen M Hiltunen M Mannermaa A Helisalmi S Lehtovirta M Hanninen T Soininen H Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women Eur J Hum Genet 2005, 13:1000-1006 10.1038/sj.ejhg.5201447 15944651
    • (2005) Eur J Hum Genet , vol.13 , pp. 1000-1006
    • Pirskanen, M.1    Hiltunen, M.2    Mannermaa, A.3    Helisalmi, S.4    Lehtovirta, M.5    Hanninen, T.6    Soininen, H.7
  • 12
    • 0034114486 scopus 로고    scopus 로고
    • An association of elevated serum gonadotropin concentrations and Alzheimer disease?
    • 10.1046/j.1365-2826.2000.00461.x 10718932
    • Bowen RL Isley JP Atkinson RL An association of elevated serum gonadotropin concentrations and Alzheimer disease? J Neuroendocrinol 2000, 12:351-354 10.1046/j.1365-2826.2000.00461.x 10718932
    • (2000) J Neuroendocrinol , vol.12 , pp. 351-354
    • Bowen, R.L.1    Isley, J.P.2    Atkinson, R.L.3
  • 14
    • 9644267082 scopus 로고    scopus 로고
    • Low free testosterone is an independent risk factor for Alzheimer's disease
    • 10.1016/j.exger.2004.06.019 15582279
    • Hogervorst E Bandelow S Combrinck M Smith AD Low free testosterone is an independent risk factor for Alzheimer's disease Exp Gerontol 2004, 39:1633-1639 10.1016/j.exger.2004.06.019 15582279
    • (2004) Exp Gerontol , vol.39 , pp. 1633-1639
    • Hogervorst, E.1    Bandelow, S.2    Combrinck, M.3    Smith, A.D.4
  • 15
    • 0028959562 scopus 로고
    • Peripheral and intracerebroventricular administration of human chorionic gonadotropin alters several hippocampus-associated behaviors in cycling female rats
    • 10.1006/hbeh.1995.1004 7782062
    • Lukacs H Hiatt ES Lei ZM Rao CV Peripheral and intracerebroventricular administration of human chorionic gonadotropin alters several hippocampus-associated behaviors in cycling female rats Horm Behav 1995, 29:42-58 10.1006/hbeh.1995.1004 7782062
    • (1995) Horm Behav , vol.29 , pp. 42-58
    • Lukacs, H.1    Hiatt, E.S.2    Lei, Z.M.3    Rao, C.V.4
  • 16
    • 0027999075 scopus 로고
    • Novel presence of luteinizing hormone/human chorionic gonadotropin (hCG) receptors and the down-regulating action of hCG on gonadotropin-releasing hormone gene expression in immortalized hypothalamic GT1-7 neurons
    • 10.1210/me.8.8.1111 7997235
    • Lei ZM Rao CV Novel presence of luteinizing hormone/human chorionic gonadotropin (hCG) receptors and the down-regulating action of hCG on gonadotropin-releasing hormone gene expression in immortalized hypothalamic GT1-7 neurons Mol Endocrinol 1994, 8:1111-1121 10.1210/ me.8.8.1111 7997235
    • (1994) Mol Endocrinol , vol.8 , pp. 1111-1121
    • Lei, Z.M.1    Rao, C.V.2
  • 17
    • 2442515246 scopus 로고    scopus 로고
    • Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition
    • 10.1074/jbc.M311993200 14871891
    • Bowen RL Verdile G Liu T Parlow AF Perry G Smith MA Martins RN Atwood CS Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition J Biol Chem 2004, 279:20539-20545 10.1074/jbc.M311993200 14871891
    • (2004) J Biol Chem , vol.279 , pp. 20539-20545
    • Bowen, R.L.1    Verdile, G.2    Liu, T.3    Parlow, A.F.4    Perry, G.5    Smith, M.A.6    Martins, R.N.7    Atwood, C.S.8
  • 18
    • 33644759357 scopus 로고    scopus 로고
    • Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP tansgenic mice
    • Casadesus G Atwood CS Bowen RL Smith MA Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP tansgenic mice. Biochem Biophys Acta 2006
    • (2006) Biochem Biophys Acta
    • Casadesus, G.1    Atwood, C.S.2    Bowen, R.L.3    Smith, M.A.4
  • 19
    • 33846959138 scopus 로고    scopus 로고
    • Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression
    • 10.1111/j.1471-4159.2006.04307.x 17241129
    • Liu T Wimalasena J Bowen RL Atwood CS Luteinizing hormone receptor mediates neuronal pregnenolone production via up-regulation of steroidogenic acute regulatory protein expression J Neurochem 2007, 100:1329-1339 10.1111/j.1471-4159.2006.04307.x 17241129
    • (2007) J Neurochem , vol.100 , pp. 1329-1339
    • Liu, T.1    Wimalasena, J.2    Bowen, R.L.3    Atwood, C.S.4
  • 21
    • 14844337011 scopus 로고    scopus 로고
    • Estrogens, progestins, menopause and neurodegeneration: Basic and clinical studies
    • 10.1007/s00018-004-4382-2 15723163
    • Simpkins JW Yang SH Wen Y Singh M Estrogens, progestins, menopause and neurodegeneration: Basic and clinical studies Cell Mol Life Sci 2005, 62:271-280 10.1007/s00018-004-4382-2 15723163
    • (2005) Cell Mol Life Sci , vol.62 , pp. 271-280
    • Simpkins, J.W.1    Yang, S.H.2    Wen, Y.3    Singh, M.4
  • 22
    • 0024299370 scopus 로고
    • Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology
    • 10.1126/science.3283935 3283935
    • Mahley RW Apolipoprotein E: Cholesterol transport protein with expanding role in cell biology Science 1988, 240:622-630 10.1126/science.3283935 3283935
    • (1988) Science , vol.240 , pp. 622-630
    • Mahley, R.W.1
  • 23
    • 33751173605 scopus 로고    scopus 로고
    • Lipoprotein receptors in Alzheimer's disease
    • 10.1016/j.tins.2006.09.002 17000013
    • Andersen OM Willnow TE Lipoprotein receptors in Alzheimer's disease Trends Neurosci 2006, 29:687-694 10.1016/j.tins.2006.09.002 17000013
    • (2006) Trends Neurosci , vol.29 , pp. 687-694
    • Andersen, O.M.1    Willnow, T.E.2
  • 24
    • 0033711033 scopus 로고    scopus 로고
    • Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function
    • 10.1210/er.21.5.551 11041448
    • Themmen APN Huhtaniemi IT Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function Endocr Rev 2000, 21:551-583 10.1210/ er.21.5.551 11041448
    • (2000) Endocr Rev , vol.21 , pp. 551-583
    • Themmen, A.P.N.1    Huhtaniemi, I.T.2
  • 25
    • 24644461526 scopus 로고    scopus 로고
    • Mutations in human gonadotropin and gonadotropin-receptor genes
    • 10.1385/ENDO:26:3:207 16034174
    • Huhtaniemi IT Themmen AP Mutations in human gonadotropin and gonadotropin-receptor genes Endocrine 2005, 26:207-217 10.1385/ ENDO:26:3:207 16034174
    • (2005) Endocrine , vol.26 , pp. 207-217
    • Huhtaniemi, I.T.1    Themmen, A.P.2
  • 26
    • 84995842414 scopus 로고
    • Identification of two point mutations in the gene coding luteinizing hormone (LH) beta-subunit, associated with immunologically anomalous LH variants
    • 10.1210/jc.78.1.107 7904610
    • Furui K Suganuma N Tsukahara S Asada Y Kikkawa F Tanaka M Ozawa T Tomoda Y Identification of two point mutations in the gene coding luteinizing hormone (LH) beta-subunit, associated with immunologically anomalous LH variants J Clin Endocrinol Metab 1994, 78:107-113 10.1210/jc.78.1.107 7904610
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 107-113
    • Furui, K.1    Suganuma, N.2    Tsukahara, S.3    Asada, Y.4    Kikkawa, F.5    Tanaka, M.6    Ozawa, T.7    Tomoda, Y.8
  • 27
    • 0033799699 scopus 로고    scopus 로고
    • Pituitary response to luteinizing hormone-releasing hormone in women with variant luteinizing hormone
    • 10.1530/eje.0.1430375 11022180
    • Takahashi K Kurioka H Ozaki T Kanasaki H Miyazaki K Karino K Pituitary response to luteinizing hormone-releasing hormone in women with variant luteinizing hormone Eur J Endocrinol 2000, 143:375-381 10.1530/ eje.0.1430375 11022180
    • (2000) Eur J Endocrinol , vol.143 , pp. 375-381
    • Takahashi, K.1    Kurioka, H.2    Ozaki, T.3    Kanasaki, H.4    Miyazaki, K.5    Karino, K.6
  • 28
    • 0038368875 scopus 로고    scopus 로고
    • Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action
    • 10.1210/jc.2002-021946 12727981
    • Muller T Gromoll J Simoni M Absence of exon 10 of the human luteinizing hormone (LH) receptor impairs LH, but not human chorionic gonadotropin action J Clin Endocrinol Metab 2003, 88:2242-2249 10.1210/jc.2002-021946 12727981
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2242-2249
    • Muller, T.1    Gromoll, J.2    Simoni, M.3
  • 31
    • 0035954324 scopus 로고    scopus 로고
    • Gender and age modify the association between APOE and AD-related neuropathology
    • 11425936
    • Ghebremedhin E Schultz C Thal DR Rub U Ohm TG Braak E Braak H Gender and age modify the association between APOE and AD-related neuropathology Neurology 2001, 56:1696-1701 11425936
    • (2001) Neurology , vol.56 , pp. 1696-1701
    • Ghebremedhin, E.1    Schultz, C.2    Thal, D.R.3    Rub, U.4    Ohm, T.G.5    Braak, E.6    Braak, H.7
  • 34
    • 0242578210 scopus 로고    scopus 로고
    • Estrogen replacement and risk of Alzheimer disease
    • author reply 1101 2
    • Smith MA Perry G Atwood CS Bowen RL Estrogen replacement and risk of Alzheimer disease Jama 2003, 289:1100; author reply 1101 2
    • (2003) Jama , vol.289 , pp. 1100
    • Smith, M.A.1    Perry, G.2    Atwood, C.S.3    Bowen, R.L.4
  • 35
    • 24644514310 scopus 로고    scopus 로고
    • The gonadotropin connection in Alzheimer's disease
    • 10.1385/ENDO:26:3:317 16034187
    • Meethal SV Smith MA Bowen RL Atwood CS The gonadotropin connection in Alzheimer's disease Endocrine 2005, 26:317-326 10.1385/ENDO:26:3:317 16034187
    • (2005) Endocrine , vol.26 , pp. 317-326
    • Meethal, S.V.1    Smith, M.A.2    Bowen, R.L.3    Atwood, C.S.4
  • 37
    • 33646829775 scopus 로고    scopus 로고
    • The impact of our genes: Consequences of the apolipoprotein E polymorphism in Alzheimer disease and multiple sclerosis
    • 10.1016/j.jns.2005.08.018 16631796
    • Fazekas F Enzinger C Ropele S Schmidt H Schmidt R Strasser-Fuchs S The impact of our genes: Consequences of the apolipoprotein E polymorphism in Alzheimer disease and multiple sclerosis J Neurol Sci 2006, 245:35-39 10.1016/j.jns.2005.08.018 16631796
    • (2006) J Neurol Sci , vol.245 , pp. 35-39
    • Fazekas, F.1    Enzinger, C.2    Ropele, S.3    Schmidt, H.4    Schmidt, R.5    Strasser-Fuchs, S.6
  • 38
    • 0032440082 scopus 로고    scopus 로고
    • An apolipoprotein E synthetic peptide selectively modulates the transcription of the gene for rat ovarian theca and interstitial cell P450 17alpha-hydroxylase, C17-20 lyase
    • 9831628
    • Zhang G Curtiss LK Wade RL Dyer CA An apolipoprotein E synthetic peptide selectively modulates the transcription of the gene for rat ovarian theca and interstitial cell P450 17alpha-hydroxylase, C17-20 lyase J Lipid Res 1998, 39:2406-2414 9831628
    • (1998) J Lipid Res , vol.39 , pp. 2406-2414
    • Zhang, G.1    Curtiss, L.K.2    Wade, R.L.3    Dyer, C.A.4
  • 39
    • 0027463431 scopus 로고
    • Cellular events involved in hormonal control of receptor-mediated endocytosis: Regulation occurs at multiple sites in the low density lipoprotein pathway, including steps beyond the receptor
    • 10.1210/en.132.1.337 8419131
    • Foster JD Strauss JF 3rd Paavola LG Cellular events involved in hormonal control of receptor-mediated endocytosis: Regulation occurs at multiple sites in the low density lipoprotein pathway, including steps beyond the receptor Endocrinology 1993, 132:337-350 10.1210/en.132.1.337 8419131
    • (1993) Endocrinology , vol.132 , pp. 337-350
    • Foster, J.D.1    Strauss III, J.F.2    Paavola, L.G.3
  • 41
    • 33745591389 scopus 로고    scopus 로고
    • Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans
    • 10.1093/hmg/ddl144 16740595
    • Yu Y Panhuysen C Kranzler HR Hesselbrock V Rounsaville B Weiss R Brady K Farrer LA Gelernter J Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans Hum Mol Genet 2006, 15:2192-2199 10.1093/hmg/ddl144 16740595
    • (2006) Hum Mol Genet , vol.15 , pp. 2192-2199
    • Yu, Y.1    Panhuysen, C.2    Kranzler, H.R.3    Hesselbrock, V.4    Rounsaville, B.5    Weiss, R.6    Brady, K.7    Farrer, L.A.8    Gelernter, J.9
  • 43
    • 26844559425 scopus 로고    scopus 로고
    • Normal and abnormal mechanisms of gene splicing and relevance to inherited skin diseases
    • 1351063 16054339 10.1016/j.jdermsci.2005.05.006
    • Wessagowit V Nalla VK Rogan PK McGrath JA Normal and abnormal mechanisms of gene splicing and relevance to inherited skin diseases J Dermatol Sci 2005, 40:73-84 1351063 16054339 10.1016/j.jdermsci.2005.05.006
    • (2005) J Dermatol Sci , vol.40 , pp. 73-84
    • Wessagowit, V.1    Nalla, V.K.2    Rogan, P.K.3    McGrath, J.A.4
  • 44
    • 18344364099 scopus 로고    scopus 로고
    • Understanding alternative splicing: Towards a cellular code
    • 10.1038/nrm1645 15956978
    • Matlin AJ Clark F Smith CW Understanding alternative splicing: Towards a cellular code Nat Rev Mol Cell Biol 2005, 6:386-398 10.1038/nrm1645 15956978
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 386-398
    • Matlin, A.J.1    Clark, F.2    Smith, C.W.3
  • 45
    • 33749989756 scopus 로고    scopus 로고
    • Method of predicting splice sites based on signal interactions
    • 1526722 16584568 10.1186/1745-6150-1-10
    • Churbanov A Rogozin IB Deogun JS Ali H Method of predicting splice sites based on signal interactions Biol Direct 2006, 1:10 1526722 16584568 10.1186/1745-6150-1-10
    • (2006) Biol Direct , vol.1 , pp. 10
    • Churbanov, A.1    Rogozin, I.B.2    Deogun, J.S.3    Ali, H.4
  • 47
    • 44349187596 scopus 로고    scopus 로고
    • Minitab v 14.0 State College, PA
    • Minitab Minitab v 14.0 State College, PA
  • 48
    • 0042629672 scopus 로고    scopus 로고
    • PyPop: A software framework for population genomics: Analyzing large-scale multi-locus genotype data
    • 12603054
    • Lancaster A Nelson MP Meyer D Thomson G Single RM PyPop: A software framework for population genomics: Analyzing large-scale multi-locus genotype data Pac Symp Biocomput 2003, 514-525 12603054
    • (2003) Pac Symp Biocomput , pp. 514-525
    • Lancaster, A.1    Nelson, M.P.2    Meyer, D.3    Thomson, G.4    Single, R.M.5
  • 49
    • 0037433052 scopus 로고    scopus 로고
    • Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions
    • 10.1093/bioinformatics/btf869 12584123
    • Hahn LW Ritchie MD Moore JH Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions Bioinformatics 2003, 19:376-382 10.1093/bioinformatics/btf869 12584123
    • (2003) Bioinformatics , vol.19 , pp. 376-382
    • Hahn, L.W.1    Ritchie, M.D.2    Moore, J.H.3
  • 50
    • 7444257916 scopus 로고    scopus 로고
    • Genetics, statistics and human disease: Analytical retooling for complexity
    • 10.1016/j.tig.2004.09.007 15522460
    • Thornton-Wells TA Moore JH Haines JL Genetics, statistics and human disease: Analytical retooling for complexity Trends Genet 2004, 20:640-647 10.1016/j.tig.2004.09.007 15522460
    • (2004) Trends Genet , vol.20 , pp. 640-647
    • Thornton-Wells, T.A.1    Moore, J.H.2    Haines, J.L.3
  • 51
    • 0030474271 scopus 로고    scopus 로고
    • A simulation study of the number of events per variable in logistic regression analysis
    • 10.1016/S0895-4356(96)00236-3 8970487
    • Peduzzi P Concato J Kemper E Holford TR Feinstein AR A simulation study of the number of events per variable in logistic regression analysis J Clin Epidemiol 1996, 49:1373-1379 10.1016/S0895-4356(96)00236-3 8970487
    • (1996) J Clin Epidemiol , vol.49 , pp. 1373-1379
    • Peduzzi, P.1    Concato, J.2    Kemper, E.3    Holford, T.R.4    Feinstein, A.R.5
  • 52
    • 0034973569 scopus 로고    scopus 로고
    • Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer
    • 1226028 11404819 10.1086/321276
    • Ritchie MD Hahn LW Roodi N Bailey LR Dupont WD Parl FF Moore JH Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer Am J Hum Genet 2001, 69:138-147 1226028 11404819 10.1086/321276
    • (2001) Am J Hum Genet , vol.69 , pp. 138-147
    • Ritchie, M.D.1    Hahn, L.W.2    Roodi, N.3    Bailey, L.R.4    Dupont, W.D.5    Parl, F.F.6    Moore, J.H.7
  • 53
    • 0345411335 scopus 로고    scopus 로고
    • The ubiquitous nature of epistasis in determining susceptibility to common human diseases
    • 10.1159/000073735 14614241
    • Moore JH The ubiquitous nature of epistasis in determining susceptibility to common human diseases Hum Hered 2003, 56:73-82 10.1159/ 000073735 14614241
    • (2003) Hum Hered , vol.56 , pp. 73-82
    • Moore, J.H.1
  • 54
    • 2942517830 scopus 로고    scopus 로고
    • An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: The importance of model validation
    • 419697 15119966 10.1186/1471-2105-5-49
    • Coffey CS Hebert PR Ritchie MD Krumholz HM Gaziano JM Ridker PM Brown NJ Vaughan DE Moore JH An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: The importance of model validation BMC Bioinformatics 2004, 5:49 419697 15119966 10.1186/ 1471-2105-5-49
    • (2004) BMC Bioinformatics , vol.5 , pp. 49
    • Coffey, C.S.1    Hebert, P.R.2    Ritchie, M.D.3    Krumholz, H.M.4    Gaziano, J.M.5    Ridker, P.M.6    Brown, N.J.7    Vaughan, D.E.8    Moore, J.H.9
  • 55
    • 33747613579 scopus 로고    scopus 로고
    • The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction
    • 10.1002/gepi.20166 16800004
    • Motsinger AA Ritchie MD The effect of reduction in cross-validation intervals on the performance of multifactor dimensionality reduction Genet Epidemiol 2006, 30:546-555 10.1002/gepi.20166 16800004
    • (2006) Genet Epidemiol , vol.30 , pp. 546-555
    • Motsinger, A.A.1    Ritchie, M.D.2
  • 56
    • 0036260234 scopus 로고    scopus 로고
    • New strategies for identifying gene-gene interactions in hypertension
    • 10.1080/07853890252953473 12108579
    • Moore JH Williams SM New strategies for identifying gene-gene interactions in hypertension Ann Med 2002, 34:88-95 10.1080/ 07853890252953473 12108579
    • (2002) Ann Med , vol.34 , pp. 88-95
    • Moore, J.H.1    Williams, S.M.2
  • 58
    • 0036187866 scopus 로고    scopus 로고
    • A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: Potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone
    • 10.1093/molehr/8.3.201 11870227
    • Jiang M Lamminen T Pakarinen P Hellman J Manna P Herrera RJ Huhtaniemi I A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: Potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone Mol Hum Reprod 2002, 8:201-212 10.1093/molehr/8.3.201 11870227
    • (2002) Mol Hum Reprod , vol.8 , pp. 201-212
    • Jiang, M.1    Lamminen, T.2    Pakarinen, P.3    Hellman, J.4    Manna, P.5    Herrera, R.J.6    Huhtaniemi, I.7
  • 59
    • 0029024292 scopus 로고
    • Structure of the human luteinizing hormone-choriogonadotropin receptor gene: Unusual promoter and 5' non-coding regions
    • 10.1016/0303-7207(95)03557-N 7556872
    • Atger M Misrahi M Sar S Le Flem L Dessen P Milgrom E Structure of the human luteinizing hormone-choriogonadotropin receptor gene: Unusual promoter and 5' non-coding regions Mol Cell Endocrinol 1995, 111:113-123 10.1016/0303-7207(95)03557-N 7556872
    • (1995) Mol Cell Endocrinol , vol.111 , pp. 113-123
    • Atger, M.1    Misrahi, M.2    Sar, S.3    Le Flem, L.4    Dessen, P.5    Milgrom, E.6


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