A PCSK9 missense variant associated with a reduced risk of early-onset myocardial infarction

New England Journal of Medicine

Volumn 358, Issue 21, 2008, Pages 2299-2300

  Kathiresan, Sekar ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KEXIN; KEXIN TYPE 9; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROPROTEIN CONVERTASE SUBTILISIN; SERINE PROTEINASE;

ALLELE; CHOLESTEROL BLOOD LEVEL; ELECTROCARDIOGRAPHY; GENERAL HOSPITAL; GENETICS; GENOTYPE; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; LETTER; MEDICAL ETHICS; PRIORITY JOURNAL; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; THORAX PAIN;

EID: 44249122796     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc0707445     Document Type: Letter

References (2)

1. JC Cohen E Boerwinkle TH Mosley Jr. HH Hobbs Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 354 2006 1264 1272
2. S Kathiresan O Melander C Guiducci Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 40 2008 189 197