Isolation of 8′-phosphate ester derivatives of amicoumacins: Structure-activity relationship of hydroxy amino acid moiety

Journal of Antibiotics

Volumn 60, Issue 12, 2007, Pages 752-756

  Hashimoto, Makoto ^a   Taguchi, Takaaki ^a   Nishida, Satoshi ^a   Ueno, Kouji ^a   Koizumi, Kaio ^a   Aburada, Masaki ^a   Ichinose, Koji ^a  

^a MUSASHINO UNIVERSITY   (Japan)

Author keywords

Amicoumacin; Anti MRSA; Dihydroisocoumarin; Phosphorylation; Structure activity relationship

Indexed keywords

ALKALINE PHOSPHATASE; AMICOUMACIN; AMICOUMACIN A; AMICOUMACIN B; ANTIINFECTIVE AGENT; HYDROXYAMINO ACID; UNCLASSIFIED DRUG; COUMARIN DERIVATIVE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS PUMILUS; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION; BACILLUS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGICAL EXAMINATION; PENICILLIN RESISTANCE; SPECTROSCOPY;

BACILLUS PUMILUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS;

ALKALINE PHOSPHATASE; ANTI-BACTERIAL AGENTS; BACILLUS; COUMARINS; METHICILLIN RESISTANCE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SPECTRUM ANALYSIS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 44249114134     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2007.99     Document Type: Article

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